scholarly journals Subcutaneous EEG Monitoring Reveals AED Response and Breakthrough Seizures

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Sigge Weisdorf ◽  
Ivan C. Zibrandtsen ◽  
Troels W. Kjaer

Unrecognized seizures are a common problem in temporal lobe epilepsy potentially leading to undertreatment. Objective seizure counting using EEG home monitoring for prolonged periods with a minimally invasive device has not been feasible until now. We present a case in which a novel, subcutaneous EEG device was utilized to provide an objective seizure count. This information revealed unrecognized breakthrough seizures and informed treatment response, prompting treatment adjustment. The case illustrates how objective seizure counting in epilepsy using new devices can completely change diagnosis and management.

Epilepsia ◽  
1996 ◽  
Vol 37 (7) ◽  
pp. 651-656 ◽  
Author(s):  
Gregory D. Cascino ◽  
Max R. Trenerry ◽  
Elson L. So ◽  
Frank W. Sharbrough ◽  
Cheolsu Shin ◽  
...  

Author(s):  
Gramegna Mario ◽  
Ponticelli Francesco ◽  
Baldetti Luca ◽  
Gallone Guglielmo ◽  
Regazzoli Damiano ◽  
...  

2008 ◽  
Vol 2 (2) ◽  
Author(s):  
Christopher P. Erdman ◽  
Stephen M. Goldman ◽  
Patrick J. Lynn ◽  
Matthew C. Ward

Blood sugar management is particularly critical in the neonatal intensive care unit where the incidence of hypoglycemia is high and patients run the risk of brain damage. The staff at most hospitals obtain glucose levels in infants by drawing blood from the heel, which is a cause for recurrent pain. Some infants undergo this procedure every 1–3hours for up to a few months. Our goal is to design a minimally invasive device that allows for real-time glucose monitoring in very low birth weight infants in the neonatal intensive care unit (NICU). This glucose monitor will reduce the amount of pain and physiological stress on the infants, decrease the risk of hypoglycemia in neonates and reduce the workload on hospital staff. There is currently much room for emerging technologies in this market as it trends towards less pain and faster responses. The device should only slightly hinder the infant’s motion, be as painless as possible, and all materials used in contact with the body need to be biologically inert and cause no irritation or allergic reaction. The device will utilize a microneedle array to extract interstitial fluid and draw it through a hydrophilic polyurethane membrane and into a polarimetry chamber. Circularly polarized light will be passed through the chamber and the differential absorbance of left and right polarized light will be used to calculate the glucose concentration. A literature and patent review showed that each separate portion could be used in an effective device for minimally invasive, continuous glucose monitoring.


Neurology ◽  
2015 ◽  
Vol 85 (17) ◽  
pp. 1475-1481 ◽  
Author(s):  
Robyn M. Busch ◽  
Thomas E. Love ◽  
Lara E. Jehi ◽  
Lisa Ferguson ◽  
Ruta Yardi ◽  
...  

Author(s):  
Tariq H. Khan

Rheo Probe is a minimally invasive device, implanted in the brain matter for patients in a coma following brain haemorrage or traumatic brain injuries to measure cerebral blood flow, intracranial pressure, temperature and oxygenation parameters. Nearinfrared sensors assess levels of tissue oxygenation as well as cerebral blood flow by measuring oxygenated and deoxygenated hemoglobin based on spectrometry.


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