Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion

Journal of Chemistry ◽

10.1155/2021/6429427 ◽

2021 ◽

Vol 2021 ◽

pp. 1-5

Author(s):

Hugo Santalla ◽

Uxía Gómez-Bouzó ◽

Irene Sánchez-Sanz ◽

Yagamare Fall

Keyword(s):

Vitamin D ◽

Research Group ◽

Ring Expansion ◽

Ring System ◽

Sulphur Atom ◽

Mild Conditions ◽

New Type ◽

Vitamin D Analogue

A new vitamin D analogue with a trans-fused decalin as the CD-ring system and containing a sulphur atom in the side chain has been synthesized in our research group. The obtention of this analogue is based on a recently discovered transformation of hydrindane cores into decalins through a dyotropic ring expansion in very mild conditions.

Download Full-text

Faculty Opinions recommendation of Topical treatment with the vitamin D analogue calcipotriol enhances the upregulation of the antimicrobial protein hCAP18/LL-37 during wounding in human skin in vivo.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3713956.3438055 ◽

2010 ◽

Author(s):

Ralf Paus ◽

Jennifer Elisabeth Klöpper

Keyword(s):

Vitamin D ◽

Topical Treatment ◽

Antimicrobial Protein ◽

Vitamin D Analogue

Download Full-text

EB 1089, a Vitamin D Analogue, Induces the Vitamin D Receptor to Form Selective Receptor Complexes Depending on Cell Type

Vitamin D ◽

10.1515/9783110882513-090 ◽

1994 ◽

pp. 255-256

Keyword(s):

Vitamin D ◽

Vitamin D Receptor ◽

Cell Type ◽

Receptor Complexes ◽

Eb 1089 ◽

Vitamin D Analogue

Download Full-text

KH 1060 - A NEW VITAMIN D ANALOGUE WITH POTENT EFFECTS ON CELL-MEDIATED IMMUNE RESPONSES IN VITRO

Vitamin D ◽

10.1515/9783110850345-167 ◽

1991 ◽

pp. 516-517 ◽

Keyword(s):

Vitamin D ◽

Immune Responses ◽

Vitamin D Analogue

Download Full-text

Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.03.081 ◽

2017 ◽

Vol 134 ◽

pp. 86-96 ◽

Author(s):

Anna Y. Belorusova ◽

Andrea Martínez ◽

Zoila Gándara ◽

Generosa Gómez ◽

Yagamare Fall ◽

...

Keyword(s):

Vitamin D ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Vitamin D Analogs ◽

Structure Activity ◽

Relationship Study

Download Full-text

ChemInform Abstract: THE BIS(TETRATHIOTUNGSTATO)DIAURATE(2-) ANION, A NEW TYPE OF INORGANIC RING SYSTEM

Chemischer Informationsdienst ◽

10.1002/chin.197813037 ◽

1978 ◽

Vol 9 (13) ◽

Author(s):

A. MUELLER ◽

H. DORNFELD ◽

G. HENKEL ◽

B. KREBS ◽

M. P. A. VIEGERS

Keyword(s):

Ring System ◽

Download Full-text

Dose finding studies of a novel vitamin D analogue 22-oxacalcitriol ointment on psoriasis vulgaris

Journal of the European Academy of Dermatology and Venereology ◽

10.1016/s0926-9959(98)95173-x ◽

1998 ◽

Vol 11 ◽

pp. S166-S167

Author(s):

H NAKAGAWA

Keyword(s):

Vitamin D ◽

Psoriasis Vulgaris ◽

Dose Finding ◽

Vitamin D Analogue

Download Full-text

The Thioacetate Approach to the Synthesis of the Side Chain of Vitamin D Metabolites and Analogues.

10.1002/chin.200347220 ◽

2003 ◽

Vol 34 (47) ◽

Author(s):

Yagamare Fall ◽

Ousmane Diouf ◽

Generosa Gomez ◽

Tamara Bolano

Keyword(s):

Vitamin D ◽

Vitamin D Metabolites

Download Full-text

ChemInform Abstract: New Type of 2-Alkyl-substituted 1,8-Naphthyridine Systems Containing a Phosphoryl Group in the Side Chain.

10.1002/chin.200834189 ◽

2008 ◽

Vol 39 (34) ◽

Author(s):

P. S. Lemport ◽

G. V. Bodrin ◽

M. P. Pasechnik ◽

A. G. Matveeva ◽

P. V. Petrovskii ◽

...

Keyword(s):

Phosphoryl Group ◽

Download Full-text

Evidence for the uptake of a vitamin D analogue (OCT) by a human carcinoma and its effect of suppressing the transcription of parathyroid hormone-related peptide gene in vivo.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)31690-9 ◽

1994 ◽

Vol 269 (51) ◽

pp. 32693-32699

Author(s):

K Endo ◽

F Ichikawa ◽

Y Uchiyama ◽

K Katsumata ◽

H Ohkawa ◽

...

Keyword(s):

Vitamin D ◽

Parathyroid Hormone ◽

Human Carcinoma ◽

Related Peptide ◽

Parathyroid Hormone Related Peptide ◽

Peptide Gene ◽

Vitamin D Analogue

Download Full-text

Vitamin D analogue therapy, cardiovascular risk and kidney function in people with Type 1 diabetes mellitus and diabetic nephropathy: a randomized trial

Diabetic Medicine ◽

10.1111/dme.12606 ◽

2014 ◽

Vol 32 (3) ◽

pp. 374-381 ◽

Author(s):

C. Joergensen ◽

L. Tarnow ◽

J. P. Goetze ◽

P. Rossing

Keyword(s):

Diabetes Mellitus ◽

Vitamin D ◽

Type 1 Diabetes ◽

Diabetic Nephropathy ◽

Cardiovascular Risk ◽

Type 1 Diabetes Mellitus ◽

Randomized Trial ◽

Kidney Function ◽

Vitamin D Analogue

Download Full-text