scholarly journals Response to: Comment on “Acetazolamide Intoxication in an Elderly Patient with Diabetes and Chronic Renal Failure after Cataract Surgery”

2021 ◽  
Vol 2021 ◽  
pp. 1-2
Author(s):  
Juliana Maria Kerber ◽  
Juliana Dias de Mello ◽  
Karolinny Borinelli de Aquino Moura ◽  
Gustavo Cardoso da Silva ◽  
Iuri Christmann Wawrzeniak ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Juliana Maria Kerber ◽  
Juliana Dias de Mello ◽  
Karolinny Borinelli de Aquino Moura ◽  
Gustavo Cardoso da Silva ◽  
Iuri Christmann Wawrzeniak ◽  
...  

Carbonic anhydrase inhibitors, such as acetazolamide, are widely used in the treatment of open-angle glaucoma. Severe metabolic acidosis is a rare complication of acetazolamide use, and life-threatening acidosis occurs most commonly in elderly patients, in patients with advanced renal failure, and in patients with diabetes. We describe an unusual case of an elderly patient with diabetic nephropathy and chronic renal failure who presented to the emergency department with severe metabolic acidosis and coma after exposure to high doses of acetazolamide in the postoperative period of ophthalmic surgery. As symptoms of acetazolamide intoxication and uremia are similar, high suspicion is required to detect excessive plasma drug concentrations and intoxication in patients presenting with concomitant uremia. Clinical symptoms are potentially reversible with prompt diagnosis and treatment, including supportive treatment, bicarbonate therapy, and renal replacement therapy. Hemodialysis is particularly helpful in the management of acetazolamide overdose as the medication is dialyzable.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Songtao Yin ◽  
Jie Zhang ◽  
Xia Hua ◽  
Guannan Huang ◽  
Biyun Jia ◽  
...  

2014 ◽  
Vol 25 ◽  
pp. v100 ◽  
Author(s):  
Oju Katayama ◽  
Takahisa Fujikawa ◽  
Yasunori Yoshimoto ◽  
Akira Tanaka

2000 ◽  
Vol 61 (5) ◽  
pp. 1199-1202
Author(s):  
Hiroyuki KIKKAWA ◽  
Yuji WATANABE ◽  
Motomichi SATO ◽  
Kazuyoshi TOKUI ◽  
Motohira YOSHIDA ◽  
...  

2021 ◽  
Vol 20 (4) ◽  
pp. 158-163
Author(s):  
Chan Woong Joo ◽  
Sung Pyo Park ◽  
Kyeong Ik Na

Purpose: To report a case of severe intraocular pressure fluctuation following hemodialysis after cataract surgery in a patient with chronic renal failure.Case summary: A 51-year-old female patient on hemodialysis for chronic renal failure, who was seen regularly by our retina clinic for proliferative diabetic retinopathy and right eye cataract, presented with decreased visual acuity in her right eye. During phacoemulsification under the diagnosis of right eye cataract, zonular dialysis and posterior capsule rupture occurred and intraocular lens ciliary sulcus insertion was performed. Following hemodialysis 3 days after the surgery, the patient complained of headache and right eye pain. The intraocular pressure of the right eye had increased to 44 mmHg. Mild inflammation in the anterior chamber was found with remnant lens material present at the inferior anterior angle. The use of glaucoma eye drops, anterior chamber paracentesis, and anterior chamber irrigation reduced the intraocular pressure and improved the patient’s symptoms. However, a severe increase in intraocular pressure recurred with the above symptoms, again following hemodialysis. Intraocular pressure fluctuation was repetitively present after serial hemodialysis treatments for 1 month, at which point cataract and glaucoma surgeries were considered. However, the intraocular pressure stabilized afterwards; thus, the patient remained under observation and was treated with glaucoma eye drops.Conclusions: Inflammation and a decrease in the aqueous outflow facility due to remnant lens material and the use of an ophthalmic viscoelastic device in cataract surgery may cause severe intraocular pressure fluctuations in patients undergoing hemodialysis for chronic renal failure.


Kanzo ◽  
2015 ◽  
Vol 56 (12) ◽  
pp. 668-674
Author(s):  
Yusuke Watanabe ◽  
Toru Ishikawa ◽  
Satoshi Abe ◽  
Ryousuke Inoue ◽  
Tomoyuki Sugano ◽  
...  

Eye ◽  
2000 ◽  
Vol 14 (2) ◽  
pp. 176-179 ◽  
Author(s):  
Dilek Dursun ◽  
Yonca A Akova ◽  
Ahmet Akman ◽  
Sibel Oto ◽  
Pinar Aydin

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