scholarly journals Construction of Ru(II) Polypyridyl Based Macrocycles: Synthesis, Characterization, Electrochemical, Li+ Binding, Antitumour and Anti-HIV properties

2001 ◽  
Vol 8 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Lallan Mishra ◽  
Ragini Sinha ◽  
P. C. Pandey
Keyword(s):  
Elemental Analysis ◽  
Binding Properties ◽  
Polypyridyl Complexes ◽  
Mass Data ◽  
Anti Hiv

Some ruthenium (II) polypyridyl complexes with a bis-chalcone (obtained by the condensation of 3-methyl-thiophene-2-carboxaldehyde and 4-acetyl pyridine) have been synthesized and characterized spectroscopically (IR, NMR, UV/Vis), conductimetric, elemental analysis and FAB mass data. Their luminescent, redox and Li+ binding properties have been studied. The anti-HIV and antitumour activities have also been reported.

scholarly journals Studies on Some New Ru(III) Complexes Using aryl-azo Pentane- 2,4-dione and 2,6-bis (2'-Benzimidazolyl) Pyridine as Ligands: Synthesis, Spectroscopic, Luminescent, Electrochemical and Biological Activities

2001 ◽  
Vol 8 (2) ◽  
pp. 65-71 ◽  
Author(s):  
Lallan Mishra ◽  
Ajay K. Yadaw ◽  
Ratna S. Phadke ◽  
Chang S. Choi ◽  
Koji Araki
Keyword(s):  
Elemental Analysis ◽  
Biological Activities ◽  
Redox Properties ◽  
Mass Data ◽  
Anti Hiv

Some ruthenium(III) complexes with aryl-azo 2,4-pentanedione as co-ligands (LH1-LH3) have been synthesized and characterized spectroscopically IR, H1 NMR, UV/Vis, ESR, conductimetric) along with elemental analysis and FAB-mass data. Their luminescent and redox properties have been studied. The antibacterial, anti-HIV and antitmnour activities have also been reported.

scholarly journals New Perfluorophtalate Complexes of Platinum(II) With Chemotherapeutic Potential

1996 ◽  
Vol 3 (3) ◽  
pp. 117-122
Author(s):  
M. B. de Oliveira ◽  
J. Miller ◽  
R. E. Banks ◽  
L. R. Kelland ◽  
C. A. McAuliffe ◽  
...  
Keyword(s):  
Ir Spectra ◽  
Ovarian Carcinoma ◽  
Elemental Analysis ◽  
Nmr Spectra ◽  
Carcinoma Cell ◽  
Acquired Resistance ◽  
Cross Resistance ◽  
Carcinoma Cell Lines ◽  
Human Ovarian Carcinoma ◽  
Anti Hiv

Two new platinum(II) complexes have been synthesized and their anti-tumour and anti-HIV activities have been evaluated.The new complexes are: (i) cis-tetrafluorophthalate-ammine-morpholine-platinum(II) or MMF3 and (ii) cis-tetrafluorophthalate- ammine-piperidine-platinum(II) or MPF4. They were characterized by elemental analysis, IR spectra and H1 and C13 NMR spectra.They were tested against five human ovarian carcinoma cell lines, viz., CH1, CH1cisR, A2780, A2780cisR and SKOV-3. They were less active than cis-platin and showed cross-resistance with cis-platin in the CH1cisR and A2780cisR acquired resistance lines.They were also tested for possible anti-HIV activity using the HIV-I IIIB virus and C8166 cells, but they were inactive compared with AZT.

Photophysical, photooxidation, and biomolecule-interaction of meso-tetra(thienyl)porphyrins containing peripheral Pt(II) and Pd(II) complexes. Insights for photodynamic therapy applications

2022 ◽  
Author(s):  
Isadora Tisoco ◽  
Maria Carolina Donatoni ◽  
Henrique Victória ◽  
José Roberto de Toledo ◽  
Klaus Krambrock ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Elemental Analysis ◽  
Synthesis And Characterization ◽  
Polypyridyl Complexes ◽  
Cationic Porphyrins ◽  
Peripheral Position

We report the synthesis and characterization of two novel tetra-cationic porphyrins, containing Pt(II) or Pd(II) polypyridyl complexes attached at the peripheral position of N4-macrocycle. Compounds were characterized through elemental analysis,...

Synthesis, photophysical, electrochemical, and ion-binding properties of Ru(II) polypyridyl complexes containing benzo-15-crown-5

2012 ◽  
Vol 37 (3) ◽  
pp. 249-255 ◽  
Author(s):  
Feixiang Cheng ◽  
Ning Tang ◽  
Pinhua Liu ◽  
Nengbang Hou ◽  
Guang Chen
Keyword(s):  
Ion Binding ◽  
Binding Properties ◽  
Polypyridyl Complexes

CHEMICO-BIOLOGICAL INTERACTION OF SELECTED TETRAHYDROPYRIMIDINES

2021 ◽  
Author(s):  
Emilija Milović ◽  
◽  
Nenad Janković ◽  
Jelena Petronijević ◽  
Nenad Joksimović
Keyword(s):  
Fluorescence Emission ◽  
Carrier Protein ◽  
Important Class ◽  
Biological Interaction ◽  
Pharmacological Activities ◽  
Binding Properties ◽  
Great Ability ◽  
Optimum Range ◽  
The Past ◽  
Anti Hiv

Tetrahydropyrimidines (THPMs) attracted attention as a very important class of aza heterocycles with broad pharmacological activities during the past years. In many studies have been proven that THPMs have anticancer, anti-inflammatory, antimicrobial, antioxidant, antifungal, anti-HIV activity. Bearing in mind our interest in medicinal and Biginelli chemistry, we investigated interaction with important biomacromolecules (DNA, BSA) and our earlier synthetized THPMs derivatives with proven very good cytotoxic activity.[1] Investigation of affinity of compounds A and B (Figure 1) to bind to bovine serum albumin (BSA) is based on the fact that the efficiency of drugs depends on their ability to bind for carrier protein. Binding properties were investigated by using the fluorescence emission titration of BSA with A and B. The obtained values of Ka, which are in optimum range which is considered to be 106-107M-1 indicate that both compounds have great ability to bind to BSA. In addition, Ka values for A-BSA and B-BSAshow that both compounds are suitable for drug-cell

Sign in / Sign up

Export Citation Format

Share Document