scholarly journals A Phase I Pharmacokinetic and Pharmacodynamic Study of the Farnesyl Transferase Inhibitor BMS-214662 in Combination with Cisplatin in Patients with Advanced Solid Tumors

2004 ◽  
Vol 10 (8) ◽  
pp. 2636-2644 ◽  
Author(s):  
Helen J. Mackay ◽  
Ronald Hoekstra ◽  
Ferry A. L. M. Eskens ◽  
Walker J. Loos ◽  
Donna Crawford ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Advanced Solid Tumors ◽  
Farnesyl Transferase ◽  
Farnesyl Transferase Inhibitor ◽  
Pharmacodynamic Study

scholarly journals Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors

2013 ◽  
Vol 20 (1) ◽  
pp. 233-245 ◽  
Author(s):  
Geoffrey I. Shapiro ◽  
Jordi Rodon ◽  
Cynthia Bedell ◽  
Eunice L. Kwak ◽  
Jose Baselga ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pi3k Inhibitor ◽  
Class I ◽  
Advanced Solid Tumors ◽  
Pharmacodynamic Study

scholarly journals Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma

2011 ◽  
Vol 30 (6) ◽  
pp. 2294-2302 ◽  
Author(s):  
Jason Konner ◽  
Rachel N. Grisham ◽  
Jae Park ◽  
Owen A. O’Connor ◽  
Gillian Cropp ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Clinical Pharmacokinetic ◽  
Advanced Solid Tumors ◽  
Epothilone D ◽  
Pharmacodynamic Study

scholarly journals A Phase I Pharmacokinetic and Pharmacodynamic Study of PX-12, a Novel Inhibitor of Thioredoxin-1, in Patients with Advanced Solid Tumors

2007 ◽  
Vol 13 (7) ◽  
pp. 2109-2114 ◽  
Author(s):  
Ramesh K. Ramanathan ◽  
D. Lynn Kirkpatrick ◽  
Chandra P. Belani ◽  
David Friedland ◽  
Sylvan B. Green ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Advanced Solid Tumors ◽  
Thioredoxin 1 ◽  
Pharmacodynamic Study

scholarly journals Phase I Pharmacokinetic and Pharmacodynamic Study of SJG-136, a Novel DNA Sequence Selective Minor Groove Cross-linking Agent, in Advanced Solid Tumors

2011 ◽  
Vol 17 (11) ◽  
pp. 3794-3802 ◽  
Author(s):  
Igor Puzanov ◽  
Wooin Lee ◽  
Alice P. Chen ◽  
M. Wade Calcutt ◽  
David L. Hachey ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dna Sequence ◽  
Minor Groove ◽  
Cross Linking ◽  
Advanced Solid Tumors ◽  
Pharmacodynamic Study
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