scholarly journals Negative Effect of DNA Hypermethylation on the Outcome of Intensive Chemotherapy in Older Patients with High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia following Myelodysplastic Syndrome

2007 ◽  
Vol 13 (23) ◽  
pp. 7107-7112 ◽  
Author(s):  
Michael Grövdal ◽  
Rasheed Khan ◽  
Anni Aggerholm ◽  
Petar Antunovic ◽  
Jan Astermark ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
High Risk ◽  
Myelodysplastic Syndrome ◽  
Myelodysplastic Syndromes ◽  
Older Patients ◽  
Myeloid Leukemia ◽  
Intensive Chemotherapy ◽  
Dna Hypermethylation ◽  
Negative Effect ◽  
Acute Myeloid

Phase I/II study of vosaroxin and decitabine in older patients (pts) with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS).

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 7098-7098
Author(s):  
Naval Guastad Daver ◽  
Hagop M. Kantarjian ◽  
Sherry Pierce ◽  
Mark Brandt ◽  
Courtney Denton Dinardo ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
High Risk ◽  
Myelodysplastic Syndrome ◽  
Phase I ◽  
Older Patients ◽  
Myeloid Leukemia ◽  
Acute Myeloid

scholarly journals Vosaroxin in combination with decitabine in newly diagnosed older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome

Haematologica ◽  
2017 ◽  
Vol 102 (10) ◽  
pp. 1709-1717 ◽  
Author(s):  
Naval Daver ◽  
Hagop Kantarjian ◽  
Guillermo Garcia-Manero ◽  
Elias Jabbour ◽  
Gautam Borthakur ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
High Risk ◽  
Myelodysplastic Syndrome ◽  
Older Patients ◽  
Myeloid Leukemia ◽  
Newly Diagnosed ◽  
Acute Myeloid

scholarly journals Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome:

Cancer ◽  
2006 ◽  
Vol 106 (5) ◽  
pp. 1090-1098 ◽  
Author(s):  
Hagop Kantarjian ◽  
Susan O'Brien ◽  
Jorge Cortes ◽  
Francis Giles ◽  
Stefan Faderl ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
High Risk ◽  
Myelodysplastic Syndrome ◽  
Myeloid Leukemia ◽  
Intensive Chemotherapy ◽  
Acute Myeloid

Intensive chemotherapy is not recommended for patients aged >60 years who have myelodysplastic syndromes or acute myeloid leukemia with high-risk karyotypes

Cancer ◽  
2007 ◽  
Vol 110 (2) ◽  
pp. 345-352 ◽  
Author(s):  
Sabine Knipp ◽  
Barbara Hildebrand ◽  
Andrea Kündgen ◽  
Aristoteles Giagounidis ◽  
Guido Kobbe ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
High Risk ◽  
Myelodysplastic Syndromes ◽  
Myeloid Leukemia ◽  
Intensive Chemotherapy ◽  
Acute Myeloid
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