Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastoma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-18-1040 ◽

2018 ◽

Vol 24 (21) ◽

pp. 5392-5406 ◽

Author(s):

Chiaki T. Ishida ◽

Yiru Zhang ◽

Elena Bianchetti ◽

Chang Shu ◽

Trang T.T. Nguyen ◽

...

Keyword(s):

Metabolic Reprogramming ◽

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Exploring Cancer Metabolic Reprogramming Through Molecular Imaging

10.3389/978-2-88945-234-7 ◽

2017 ◽

Keyword(s):

Molecular Imaging ◽

Metabolic Reprogramming

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Faculty Opinions recommendation of The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13485020.14872066 ◽

2012 ◽

Author(s):

David Fruman

Keyword(s):

Transcription Factor ◽

T Lymphocyte ◽

Lymphocyte Activation ◽

Metabolic Reprogramming ◽

T Lymphocyte Activation

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Faculty Opinions recommendation of The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13485020.14862147 ◽

2012 ◽

Author(s):

Laurence Morel

Keyword(s):

Transcription Factor ◽

T Lymphocyte ◽

Lymphocyte Activation ◽

Metabolic Reprogramming ◽

T Lymphocyte Activation

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Faculty Opinions recommendation of Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717997786.793481059 ◽

2013 ◽

Author(s):

Mark Boothby

Keyword(s):

Cell Differentiation ◽

T Cell ◽

Amino Acid Transport ◽

T Cell Differentiation ◽

Metabolic Reprogramming ◽

Acid Transport ◽

Antigen Receptors

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Faculty Opinions recommendation of PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725405105.793505640 ◽

2015 ◽

Author(s):

Larry Kane

Keyword(s):

T Cell ◽

Fatty Acid Oxidation ◽

Metabolic Reprogramming ◽

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Faculty Opinions recommendation of Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725566014.793533998 ◽

2017 ◽

Author(s):

Paula Oliver

Keyword(s):

Metabolic Reprogramming ◽

Th1 Cell ◽

Cell Responses ◽

Nutrient Influx

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Faculty Opinions recommendation of Metabolic reprogramming of pancreatic cancer mediated by CDK4/6 inhibition elicits unique vulnerabilities.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726100304.793514138 ◽

2016 ◽

Author(s):

Julien Sage

Keyword(s):

Pancreatic Cancer ◽

Metabolic Reprogramming

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Faculty Opinions recommendation of Viral metabolic reprogramming in marine ecosystems.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726304636.793534824 ◽

2017 ◽

Author(s):

Roberto Danovaro

Keyword(s):

Marine Ecosystems ◽

Metabolic Reprogramming

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Faculty Opinions recommendation of HIF1α and metabolic reprogramming in inflammation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726694237.793541826 ◽

2018 ◽

Author(s):

Suzanne Crowe

Keyword(s):

Metabolic Reprogramming

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Faculty Opinions recommendation of Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726777837.793528950 ◽

2017 ◽

Author(s):

Pilar Santisteban ◽

Garcilaso Riesco-Eizaguirre

Keyword(s):

Thyroid Cancers ◽

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