Abstract 3657: MCM7, ADAM10, TRIM29, Aurora Kinase B, and Cyclin D1: A panel of prognostic protein markers for progression in non-muscle invasive bladder cancer - a multicenter tissue microarray validation study

2012 ◽  
Author(s):  
Niels Fristrup ◽  
Karin Birkenkamp-Demtröder ◽  
Benedicte Ulhøi ◽  
Francisco Mansilla ◽  
Marta Sanchez-Carbayo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cyclin D1 ◽  
Tissue Microarray ◽  
Validation Study ◽  
Aurora Kinase ◽  
Invasive Bladder Cancer ◽  
Protein Markers ◽  
Muscle Invasive Bladder Cancer ◽  
Aurora Kinase B ◽  
Muscle Invasive

scholarly journals Multicenter Validation of Cyclin D1, MCM7, TRIM29, and UBE2C as Prognostic Protein Markers in Non-Muscle–Invasive Bladder Cancer

2013 ◽  
Vol 182 (2) ◽  
pp. 339-349 ◽  
Author(s):  
Niels Fristrup ◽  
Karin Birkenkamp-Demtröder ◽  
Thomas Reinert ◽  
Marta Sanchez-Carbayo ◽  
Ulrika Segersten ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cyclin D1 ◽  
Invasive Bladder Cancer ◽  
Protein Markers ◽  
Muscle Invasive Bladder Cancer ◽  
Muscle Invasive ◽  
Multicenter Validation

Cathepsin E, Maspin, Plk1, and Survivin Are Promising Prognostic Protein Markers for Progression in Non-Muscle Invasive Bladder Cancer

2012 ◽  
Vol 180 (5) ◽  
pp. 1824-1834 ◽  
Author(s):  
Niels Fristrup ◽  
Benedicte P. Ulhøi ◽  
Karin Birkenkamp-Demtröder ◽  
Francisco Mansilla ◽  
Marta Sanchez-Carbayo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Invasive Bladder Cancer ◽  
Protein Markers ◽  
Muscle Invasive Bladder Cancer ◽  
Cathepsin E ◽  
Muscle Invasive

Abstract 3656: Cathepsin E, Maspin, PLK1, and Survivin are promising prognostic protein markers for progression in non-muscle invasive bladder cancer

2012 ◽  
Author(s):  
Niels Fristrup ◽  
Benedicte Parm Ulhøi ◽  
Karin Birkenkamp-Demtröder ◽  
Francisco Mansilla ◽  
Marta Sanchez-Carbayo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Invasive Bladder Cancer ◽  
Protein Markers ◽  
Muscle Invasive Bladder Cancer ◽  
Cathepsin E ◽  
Muscle Invasive

Prognostic Impact of a 12-gene Progression Score in Non–muscle-invasive Bladder Cancer: A Prospective Multicentre Validation Study

2017 ◽  
Vol 72 (3) ◽  
pp. 461-469 ◽  
Author(s):  
Lars Dyrskjøt ◽  
Thomas Reinert ◽  
Ferran Algaba ◽  
Emil Christensen ◽  
Daan Nieboer ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Validation Study ◽  
Invasive Bladder Cancer ◽  
Prognostic Impact ◽  
Muscle Invasive Bladder Cancer ◽  
Muscle Invasive

scholarly journals Detection of Circulating Serum Protein Biomarkers of Non-Muscle Invasive Bladder Cancer after Protein Corona-Silver Nanoparticles Analysis by SWATH-MS

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2384
Author(s):  
Benito Blanco Gómez ◽  
Rubén López-Cortés ◽  
Francisco Javier Casas-Nebra ◽  
Sergio Vázquez-Estévez ◽  
Daniel Pérez-Fentes ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Silver Nanoparticles ◽  
Serum Protein ◽  
Protein Corona ◽  
Coagulation Cascade ◽  
Invasive Bladder Cancer ◽  
Protein Markers ◽  
Serum Samples ◽  
Muscle Invasive Bladder Cancer ◽  
Muscle Invasive

Because cystoscopy is expensive and invasive, a new method of detecting non-invasive muscular bladder cancer (NMIBC) is needed. This study aims to identify potential serum protein markers for NMIBC to improve diagnosis and to find treatment approaches that avoid disease progression to a life-threatening phenotype (muscle-invasive bladder cancer, MIBC). Here, silver nanoparticles (AgNPs, 9.73 ± 1.70 nm) as a scavenging device together with sequential window acquisition of all theoretical mass spectra (SWATH-MS) were used to quantitatively analyze the blood serum protein alterations in two NMIBC subtypes, T1 and Ta, and they were compared to normal samples (HC). NMIBC’s analysis of serum samples identified three major groups of proteins, the relative content of which is different from the HC content: proteins implicated in the complement and coagulation cascade pathways and apolipoproteins. In conclusion, many biomarker proteins were identified that merit further examination to validate their useful significance and utility within the clinical management of NMIBC patients.

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