Abstract 5863: RGX-202, a first-in-class small-molecule inhibitor of the creatine transporter SLC6a8, is a robust suppressor of cancer growth and metastatic progression

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Author(s):  
Isabel Kurth ◽  
Celia Andreu ◽  
Shugaku Takeda ◽  
Helen Tian ◽  
Foster Gonsalves ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Metastatic Progression ◽  
Creatine Transporter ◽  
Molecule Inhibitor

scholarly journals A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo

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Vol 9 (5) ◽  
pp. 1136-1146 ◽  
Author(s):  
Kuzhuvelil B. Harikumar ◽  
Ajaikumar B. Kunnumakkara ◽  
Nobuo Ochi ◽  
Zhimin Tong ◽  
Amit Deorukhkar ◽  
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Keyword(s):  
Pancreatic Cancer ◽  
Protein Kinase ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Protein Kinase D ◽  
Molecule Inhibitor

scholarly journals A covalent small molecule inhibitor of glutamate-oxaloacetate transaminase 1 impairs pancreatic cancer growth

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Vol 522 (3) ◽  
pp. 633-638 ◽  
Author(s):  
Tomohiro Yoshida ◽  
Shingo Yamasaki ◽  
Osamu Kaneko ◽  
Naofumi Taoka ◽  
Yusuke Tomimoto ◽  
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Keyword(s):  
Pancreatic Cancer ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Glutamate Oxaloacetate Transaminase ◽  
Molecule Inhibitor

scholarly journals A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo

EBioMedicine ◽  
2017 ◽  
Vol 25 ◽  
pp. 22-31 ◽  
Author(s):  
Seung Ho Shin ◽  
Do Young Lim ◽  
Kanamata Reddy ◽  
Margarita Malakhova ◽  
Fangfang Liu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Molecule Inhibitor

scholarly journals A Small Molecule Inhibitor of ETV1, YK-4-279, Prevents Prostate Cancer Growth and Metastasis in a Mouse Xenograft Model

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e114260 ◽  
Author(s):  
Said Rahim ◽  
Tsion Minas ◽  
Sung-Hyeok Hong ◽  
Sarah Justvig ◽  
Haydar Çelik ◽  
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Keyword(s):  
Prostate Cancer ◽  
Small Molecule ◽  
Xenograft Model ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Mouse Xenograft ◽  
Molecule Inhibitor ◽  
Mouse Xenograft Model

scholarly journals A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

2013 ◽  
Vol 13 (3) ◽  
pp. 565-575 ◽  
Author(s):  
Fardokht Abulwerdi ◽  
Chenzhong Liao ◽  
Meilan Liu ◽  
Asfar S. Azmi ◽  
Amro Aboukameel ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Molecule Inhibitor

scholarly journals C644‐0303, A Small Molecule Inhibitor of Wnt/β‐catenin Pathway, Suppresses Colorectal Cancer Growth

2021 ◽  
Author(s):  
Yu Yan ◽  
Yidan Zhang ◽  
Mengyuan Li ◽  
Yazhuo Zhang ◽  
Xinxin Zhang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Molecule Inhibitor

414 A Novel Small Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth Both In Vitro and In Vivo

2010 ◽  
Vol 138 (5) ◽  
pp. S-62 ◽  
Author(s):  
Christopher R. Ireson ◽  
Kuzhuvelil B. Harikumar ◽  
Ajaykumar B. Kunnumakkara ◽  
Amit Deorukhkar ◽  
Zhimin Tong ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Protein Kinase ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Growth ◽  
Protein Kinase D ◽  
Molecule Inhibitor
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