Abstract 1169: Characterization of a small molecule inhibitor for GD3 synthase (ST8SIA1), a novel target in breast cancer stem-like cells

Mapping Intimacies ◽

10.1158/1538-7445.am2019-1169 ◽

2019 ◽

Author(s):

Appalaraju Jappupilli ◽

Khoa Nguyen ◽

Stanley Ly ◽

Michael Andreeff ◽

Prashen Chelikani ◽

...

Keyword(s):

Breast Cancer ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Gd3 Synthase ◽

Novel Target

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Abstract 1169: Characterization of a small molecule inhibitor for GD3 synthase (ST8SIA1), a novel target in breast cancer stem-like cells

10.1158/1538-7445.sabcs18-1169 ◽

2019 ◽

Author(s):

Appalaraju Jappupilli ◽

Khoa Nguyen ◽

Stanley Ly ◽

Michael Andreeff ◽

Prashen Chelikani ◽

...

Keyword(s):

Breast Cancer ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Gd3 Synthase ◽

Novel Target

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Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1283961.751061 ◽

2009 ◽

Author(s):

Marie-France Carlier

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Actin Assembly ◽

Molecule Inhibitor ◽

Identification And Characterization

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QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model

Breast Cancer Research ◽

10.1186/bcr2252 ◽

2009 ◽

Vol 11 (3) ◽

Cited By ~ 43

Author(s):

Jessica Kalra ◽

Corinna Warburton ◽

Karen Fang ◽

Lincoln Edwards ◽

Tim Daynard ◽

...

Keyword(s):

Breast Cancer ◽

Treatment Outcomes ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Cancer Model ◽

Synergistic Interactions ◽

Molecule Inhibitor ◽

Breast Cancer Model ◽

Integrin Linked Kinase

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Abstract LB-209: Identification and characterization of small molecule inhibitor of Wnt canonical pathway in a glioma setting.

10.1158/1538-7445.am2012-lb-209 ◽

2012 ◽

Author(s):

Alessandra De Robertis ◽

Silvia Valensin ◽

Marco Rossi ◽

Margherita Verani ◽

Patrizia Tunici ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Canonical Pathway ◽

Molecule Inhibitor ◽

Identification And Characterization

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Abstract 3228: Characterization of a novel, orally bioavailable, potent and highly selective small molecule inhibitor of PERK: A tool to probe the biphasic concentration-dependent induction of ER stress in models of multiple myeloma and B-cell lymphoma

10.1158/1538-7445.am2014-3228 ◽

2014 ◽

Author(s):

Ian Stansfield ◽

Yannick Ligny ◽

Yvan Simonnet ◽

Christophe Demestre ◽

Nathalie Amblard ◽

...

Keyword(s):

Multiple Myeloma ◽

Er Stress ◽

B Cell ◽

Small Molecule ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Orally Bioavailable

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Abstract 3944: MKI-1 is a small molecule inhibitor of MASTL with antitumor and radiosensitizer activity in breast cancer cells

10.1158/1538-7445.am2019-3944 ◽

2019 ◽

Author(s):

Ah-Young Kim ◽

Jae-Sung Kim

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Small Molecule ◽

Breast Cancer Cells ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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Abstract 4484: Discovery and in vitro characterization of AMG 510–a potent and selective covalent small-molecule inhibitor of KRASG12C

10.1158/1538-7445.sabcs18-4484 ◽

2019 ◽

Cited By ~ 1

Author(s):

Anne Y. Saiki ◽

Kevin Gaida ◽

Karen Rex ◽

Pragathi Achanta ◽

Tisha San Miguel ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

In Vitro Characterization ◽

Molecule Inhibitor

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Combined administration of a small-molecule inhibitor of TRAF6 and Docetaxel reduces breast cancer skeletal metastasis and osteolysis

Cancer Letters ◽

10.1016/j.canlet.2020.05.021 ◽

2020 ◽

Vol 488 ◽

pp. 27-39 ◽

Cited By ~ 1

Author(s):

Ryan T. Bishop ◽

Silvia Marino ◽

Giovana Carrasco ◽

Boya Li ◽

Richard J. Allen ◽

...

Keyword(s):

Breast Cancer ◽

Small Molecule ◽

Skeletal Metastasis ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Combined Administration

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A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts

PLoS ONE ◽

10.1371/journal.pone.0100993 ◽

2014 ◽

Vol 9 (6) ◽

pp. e100993 ◽

Cited By ~ 56

Author(s):

Fei Huang ◽

Alexander V. Mazin

Keyword(s):

Breast Cancer ◽

Cancer Cell ◽

Breast Cancer Cell ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Therapeutic Agents ◽

Cell Killing ◽

Molecule Inhibitor ◽

Human Rad51

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398 POSTER Discovery and characterization of a small molecule inhibitor of human Cdc7 kinase

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(06)70403-7 ◽

2006 ◽

Vol 4 (12) ◽

pp. 122

Author(s):

C. Santocanale ◽

A. Montagnoli ◽

P. Tenca ◽

M. Menichincheri ◽

B. Valsasina ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Cdc7 Kinase

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