Abstract PR-006: Integrative genomic characterization of therapeutic targets for pancreatic cancer

2021 ◽  
Author(s):  
Jimmy A. Guo ◽  
Daniel Zhao ◽  
Scott P. Ginebaugh ◽  
Steven Wang ◽  
Ananya D. Jambhale ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Targets ◽  
Genomic Characterization

Abstract 3036: Real-time genomic characterization of metastatic pancreatic cancer to enable precision medicine

2017 ◽  
Author(s):  
Andrew J. Aguirre ◽  
Scott Carter ◽  
Nicholas Camarda ◽  
Arezou Ghazani ◽  
Jonathan Nowak ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Precision Medicine ◽  
Real Time ◽  
Metastatic Pancreatic Cancer ◽  
Genomic Characterization

Rhabdomyosarcoma, Ewing Sarcoma, and Other Round Cell Sarcomas

2018 ◽  
Vol 36 (2) ◽  
pp. 168-179 ◽  
Author(s):  
Alberto S. Pappo ◽  
Uta Dirksen
Keyword(s):  
Ewing Sarcoma ◽  
Therapeutic Targets ◽  
Genomic Rearrangements ◽  
Round Cell ◽  
Tumor Subtypes ◽  
Specific Tumor ◽  
Genomic Characterization ◽  
Round Cell Tumors ◽  
Made In

Several recent advances have been made in the diagnosis and therapy of malignant small round cell tumors that affect children, particularly in rhabdomyosarcoma, Ewing sarcoma, and other round cell sarcomas. These advances have provided new insights into the pathologic, histologic, and genomic characterization of specific tumor subtypes, which has led to the identification of novel therapeutic targets and improved stratification of risk. This has, in turn, led to improved efficacy in clinical trials of new drug combinations, thereby increasing the survival of patients with newly diagnosed and refractory or recurrent round cell sarcomas. Here, we review the progress that has been made using genomics to identify novel pathologic genomic rearrangements, as well as therapeutic targets. We also describe how clinical and molecular factors have helped refine risk stratification and therapies that have led to improved clinical outcomes in patients with round cell sarcomas.

scholarly journals AB043. P014. Genomic characterization of pancreatic cancer in Chinese population

2018 ◽  
Vol 1 (1) ◽  
pp. AB043-AB043
Author(s):  
Wentao Gao ◽  
Kai Zhang ◽  
Zipeng Lu ◽  
Jishu Wei ◽  
Junli Wu ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chinese Population ◽  
Genomic Characterization

scholarly journals Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

2015 ◽  
Vol 5 (11) ◽  
pp. 1164-1177 ◽  
Author(s):  
Priscilla K. Brastianos ◽  
Scott L. Carter ◽  
Sandro Santagata ◽  
Daniel P. Cahill ◽  
Amaro Taylor-Weiner ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Therapeutic Targets ◽  
Genomic Characterization ◽  
Branched Evolution

scholarly journals Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine

2018 ◽  
Vol 8 (9) ◽  
pp. 1096-1111 ◽  
Author(s):  
Andrew J. Aguirre ◽  
Jonathan A. Nowak ◽  
Nicholas D. Camarda ◽  
Richard A. Moffitt ◽  
Arezou A. Ghazani ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Precision Medicine ◽  
Real Time ◽  
Advanced Pancreatic Cancer ◽  
Genomic Characterization

Genomic characterization of γ-terpinene synthase from Thymus caespititius

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
AS Lima ◽  
B Lukas ◽  
J Novak ◽  
AC Figueiredo ◽  
LG Pedro ◽  
...  
Keyword(s):  
Genomic Characterization
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