Comprehensive genomic characterization of hepatocellular carcinoma to reveal novel therapeutic targets.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e15643-e15643
Author(s):  
Yuewei Zhang ◽  
Yan Ding
2016 ◽  
Vol 18 (suppl_4) ◽  
pp. iv46-iv46
Author(s):  
A. Schuster ◽  
S. Bougnaud ◽  
O. Keunen ◽  
A. Oudin ◽  
B. Klink ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Yanan Jiang ◽  
Xiuyun Shen ◽  
Moyondafoluwa Blessing Fasae ◽  
Fengnan Zhi ◽  
Lu Chai ◽  
...  

Hepatocellular carcinoma (HCC) is among the most common and lethal form of cancer worldwide. However, its diagnosis and treatment are still dissatisfactory, due to limitations in the understanding of its pathogenic mechanism. Therefore, it is important to elucidate the molecular mechanisms and identify novel therapeutic targets for HCC. Circadian rhythm-related genes control a variety of biological processes. These genes play pivotal roles in the initiation and progression of HCC and are potential diagnostic markers and therapeutic targets. This review gives an update on the research progress of circadian rhythms, their effects on the initiation, progression, and prognosis of HCC, in a bid to provide new insights for the research and treatment of HCC.


Author(s):  
Jimmy A. Guo ◽  
Daniel Zhao ◽  
Scott P. Ginebaugh ◽  
Steven Wang ◽  
Ananya D. Jambhale ◽  
...  

Cell ◽  
2017 ◽  
Vol 169 (7) ◽  
pp. 1327-1341.e23 ◽  
Author(s):  
Adrian Ally ◽  
Miruna Balasundaram ◽  
Rebecca Carlsen ◽  
Eric Chuah ◽  
Amanda Clarke ◽  
...  

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