Cerebral Venous Thrombosis Complicated by Hemorrhagic Infarction: Factors Affecting the Initiation and Safety of Anticoagulation

Background: Diagnosis of Cerebral venous thrombosis (CVT) is challenging as it is an uncommon cause of stroke with varied clinical presentations, predisposing factors, imaging findings, and outcomes. Prompt and accurate diagnosis is important for timely intervention in order to reverse and significantly reduce the acute and long-term sequel. Aims and objectives was to study cerebral venous thrombosis in pregnant and post-partum women.Methods: Hundred pregnant and postpartum women having CVT were studied at Kamla Raja Hospital and JA Group of Hospital at GR Medical College, Gwalior Madhya Pradesh for study period of 2016 to 2017. All the women had undergone CT/MRI and MRV.Results: Age of CVT patients ranged from 18-35 years with a maximum incidence (84%) in the 2nd decade (20-30 years). Sixty two percent women had infarction; out of that 53% had hemorrhagic infarction. Frontal lobe (10%) and temporal lobe (10%) were more affected. Superior sagittal sinus (SSS) was most commonly involved (71%) followed by transverse sinus (66%) and sigmoid sinus (45%). Superficial venous system was involved in 32 patients while deep venous system was involved in 20 patients. Majority of (82%) patients had combination of sinuses and venous involvement.Conclusions: CVT was more prevalent in young pregnant and postpartum women. Hemorrhagic infarction were common and affecting frontal and temporal lobe. SSS were mostly affected in CVT. MRV should be the first line diagnostic tool for diagnosis of CVT in pregnant and postpartum women.

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Cerebral Venous Thrombosis Complicated by Hemorrhagic Infarction Secondary to Ventriculoperitoneal Shunting

Journal of Korean Neurosurgical Society ◽

10.3340/jkns.2010.48.4.357 ◽

2010 ◽

Vol 48 (4) ◽

pp. 357 ◽

Cited By ~ 1

Author(s):

Won-Soo Son ◽

Jaechan Park

Keyword(s):

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Hemorrhagic Infarction ◽

Ventriculoperitoneal Shunting

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Clinical profile of postpartum cerebral venous thrombosis

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20170891 ◽

2017 ◽

Vol 6 (4) ◽

pp. 1192

Author(s):

Umesh G. Rajoor ◽

Seema B. N.

Keyword(s):

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Clinical Profile ◽

Coagulation System ◽

Common Finding ◽

Prothrombotic State ◽

Hemorrhagic Infarction ◽

Economic Class ◽

Presenting Symptoms ◽

Laboratory Investigations

Background: Pregnancy and puerperium are most prevalent prothrombotic states leading to cerebral venous thrombosis (CVT). Pregnancy induces several changes in coagulation system, which persists at least during early puerperium, rendering it a prothrombotic state. The objective of the study was to study the clinical profile of postpartum CVT.Methods: A total of 32 consecutive patients admitted in medicine and obstetrics and gynecology ward between April 2012 and March 2015 with radiologically confirmed diagnosis of CVT were included in the study. Detailed history, clinical examination, and laboratory investigations were carried out in all the cases.Results: Out of 32 patients of CVT studied, the age of patients varied from 18 to 40 years. Maximum incidence was seen in 21-30 age group comprising 74% of the cases, with mean age being 25.5 years. Two-third of the patients belongs to the low socio-economic class. The majority of them had subacute presentation with the headache in 93.75%, followed by altered sensorium (90.6%) and convulsions (75%) being the most common presenting symptoms. Radiologically the most common finding noted was hemorrhagic infarction (85.3%), followed by non-hemorrhagic infarction (15.7%).Conclusions: Pregnancy and puerperium are most prevalent prothrombotic states leading to CVT.

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Cerebral venous thrombosis due to high-altitude polycythemia

Journal of Neurosurgery ◽

10.3171/jns.1986.64.1.0148 ◽

1986 ◽

Vol 64 (1) ◽

pp. 148-150 ◽

Cited By ~ 26

Author(s):

Takamitsu Fujimaki ◽

Masao Matsutani ◽

Akio Asai ◽

Takeshi Kohno ◽

Morio Koike

Keyword(s):

Venous Thrombosis ◽

High Altitude ◽

Cerebral Angiography ◽

Cerebral Venous Thrombosis ◽

Pathological Examination ◽

Content Type ◽

Hemorrhagic Infarction ◽

Intratumoral Hemorrhage ◽

Cortical Venous Thrombosis ◽

Fine Print

✓ A case of cerebral venous thrombosis due to polycythemia secondary to adaptation to a high altitude is reported. A 27-year-old previously healthy man developed severe neurological symptoms after climbing 8511m. Computerized tomography and cerebral angiography suggested hemorrhagic infarction or intratumoral hemorrhage, and a craniotomy was performed. Pathological examination confirmed the diagnosis of hemorrhagic infarction secondary to cortical venous thrombosis. The etiology and incidence of cerebral venous thrombosis secondary to polycythemia are discussed.

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