Total Body Water and Body Cell Mass in Normal Weight Healthy Adults

Pendahuluan. Bioelectric Impedance Analysis (BIA) mulai banyak digunakan dalam mengevaluasi status nutrisi. Belum ada data penelitian nutrisi di Indonesia yang menggunakan BIA. Penelitian ini dilakukan untuk mengetahui perbedaan rerata hasil pemeriksaan BIA antara status nutrisi baik dan malnutrisi pada penderita penyakit gastrointestinal dan hati yang dirawat inap. Metode. Penelitian potong lintang retrospektif terhadap penderita yang dirawat inap di ruang perawatan interna RSCM periode 1 Juni-31 Desember 2013, untuk mengetahui perbedaan rerata hasil pemeriksaan BIA penderita status nutrisi baik dan malnutrisi pada penyakit gastrointestinal dan hati yang dirawat inap.Hasil. Dari 28 penderita dengan status nutrisi baik, 71,57% laki-laki, dan 21,47% wanita. Dari 28 penderita malnutrisi, 53,60% laki-laki, dan 46,40% wanita. Rerata hasil pemeriksaan BIA antara penderita nutrisi baik dan malnutrisi adalah: lean body mass, 49,5 ± 8,59 v s39,68 ± 6,28kg, p<0,001; body cell mass, 32,19 (20,49-40,95) vs 25,23 (17,83-31,64) kg, p=0,003; total body water, 35,69±1,17 vs 28,58±0,85 kg, p<0,001; dan phase angle 6,18◦(3,73-10,11)◦ vs 3,46◦ (0,40-6,51)◦; , p<0,001. Simpulan. Pada penderita penyakit gastrointestinal dan hati yang dirawat inap dengan status nutrisi baik, memiliki nilai body mass, body cell mass,total body water dan phase angle hasil pemeriksaan BIA yang lebih tinggi dibandingkan dengan penderita malnutrisi.

Download Full-text

Abnormalities of Body Composition in Peritoneal Dialysis Patients

Peritoneal Dialysis International ◽

10.1177/089686080402400208 ◽

2004 ◽

Vol 24 (2) ◽

pp. 169-175 ◽

Cited By ~ 14

Author(s):

Graham Woodrow ◽

Brian Oldroyd ◽

Antony Wright ◽

W. Andrew Coward ◽

John H. Turney ◽

...

Keyword(s):

Serum Albumin ◽

Cell Mass ◽

Body Water ◽

Healthy Controls ◽

Body Cell Mass ◽

Extracellular Water ◽

Body Cell ◽

Nutrition And Hydration ◽

Water Volumes ◽

Total Body

Objectives Body composition changes occur in peritoneal dialysis (PD) due to abnormalities in nutrition and hydration. We investigated abnormalities of nutrition and hydration in PD patients compared with healthy controls by measurement of total body potassium (TBK) and body water compartments. Design Cross-sectional comparison study. Methods We measured TBK — an indicator of body cell mass — by whole body counting, total body water (TBW) by deuterium oxide dilution, and extracellular water (ECW) by bromide dilution in 29 PD patients and 32 controls. Results The absolute mean value of TBK for PD patients was not significantly lower than in controls. The ratios of observed TBK to predicted TBK from prediction formulas were compared. Equations used were those of Boddy, Bruce, Burkinshaw, and Ellis and our own equation derived from a local control database (Leeds). Observed/predicted ratios of TBK were significantly less in PD than in control subjects for all equations. Water volumes did not differ between PD and control groups. Observed/predicted ratios for TBK in PD patients correlated with serum potassium (Boddy r = 0.355, p = 0.06; Bruce r = 0.411, p < 0.05; Burkinshaw r = 0.457, p < 0.01; Leeds r = 0.412, p ≤ 0.05; Ellis r = 0.356, p = 0.06) and tended to correlate with serum albumin (Bruce r = 0.343, p = 0.07; Burkinshaw r = 0.421, p < 0.05; Leeds r = 0.357, p = 0.06; Ellis r = 0.310, p = NS). There was no relationship with serum potassium in controls. Serum albumin in PD correlated with TBK ( r = 0.445, p < 0.02), TBK/height ( r = 0.419, p < 0.05), TBK/weight ( r = 0.554, p = 0.002), and TBK/TBW ( r = 0.586, p = 0.0001). Extracellular water/intracellular water (ECW/ICW) was inversely related to TBK ( r = –0.455, p < 0.02 in PD; r = –0.387, p < 0.05 in controls) and to TBK/height ( r = –0.446, p < 0.02 in PD; r = –0.411, p = 0.02 in controls). TBK/weight reduced with age in PD ( r = –0.445, p < 0.02), as did TBK/TBW in PD ( r = –0.463, p < 0.02). ECW/ICW tended to increase with age in PD ( r = 0.351, p = 0.06). Conclusions Observed/predicted ratio of TBK is reduced in PD patients relative to healthy controls, indicating reduced body cell mass. Serum albumin and potassium reflect TBK indices in PD. Body water volumes did not differ between PD and controls, implying no overall abnormality in hydration in the PD group. However, ECW is relatively increased compared to ICW with decreasing TBK indices, suggesting relative ECW expansion with reduction in body cell mass.

Download Full-text