Intraoperative Electrical Stimulation of the Brain in Patients with Obsessive-Compulsive Neurosis

1988 ◽  
Vol 51 (6) ◽  
pp. 317-323 ◽  
Author(s):  
Lauri V. Laitinen ◽  
Evangelos Singounas
1986 ◽  
Vol 149 (3) ◽  
pp. 315-319 ◽  
Author(s):  
P. A. Kettl ◽  
I. M. Marks

Two patients are described in whom an obsessive-compulsive disorder began just after the onset of epilepsy. Neurological factors in OCD are then reviewed, and clinical reports of patients with OCD and co-existing brain pathology, EEG abnormalities, CT scan changes and electrical stimulation of the brain discussed. It is concluded that neurological factors are present in only a minority of cases of OCD. Successful behavioural treatment is independent of such factors.


CNS Spectrums ◽  
2000 ◽  
Vol 5 (11) ◽  
pp. 35-39 ◽  
Author(s):  
Bart Nuttin ◽  
Loes Gabriëls ◽  
Paul Cosyns ◽  
Jan Gybels

AbstractDespite advances in therapies, there remain psychiatric patients who are extremely ill and cannot be helped by classic psychiatric treatments, including psychotherapy and drug therapy. Certain of these patients may be helped by use of bilateral brain lesioning. The complication rate of standard stereotactic psychosurgery techniques is very low. The main rationale for the continued experimental use of deep brain stimulation (DBS) in neurosurgery for mental disorders is its reversibility. This reversibility is not an advantage in terms of the benefits obtained, but rather if side effects emerge. In addition, electrical stimulation may provide patients with some autonomy for their treatment. The first, very preliminary results of electrical stimulation for obsessive-compulsive disorder and for a small heterogeneous group of patients with other psychiatric disorders have been published. Electrical stimulation of the brain for psychiatric disorders may become a new treatment option for certain intractable psychiatric disorders. Nevertheless, the mechanism of action of DBS in psychiatric disorders is unknown, and the experience with this modality is extremely limited. The first results look promising, but this treatment option may prove unusable for some time because of a lack of knowledge of appropriate brain stimulation targets and technical problems such as the availability of sufficient current supply.


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