Effect Throughout the Day of Inhaled Fenoterol on the Bronchial Responsiveness to Histamine in Asthmatic Patients

The aim of the present study was to compare, during the pollen season, serum levels of total IgE and soluble CD23 (sCD23) from patients with allergic bronchial asthma, with those from healthy subjects. Significantly higher levels of total IgE and sCD23 were found in patients with asthma compared to the control group. Both in normal controls and in asthmatic patients, a significant correlation was shown between the levels of these two molecules. In asthmatic patients, significant correlations were found for both total IgE and sCD23, with lung function measured as bronchial responsiveness to inhaled methacholine. These results suggest that in asthmatic patients, in addition to the study of total serum IgE levels, the assessment of sCD23 serum levels may be helpful in the evaluation of disease activity.

Download Full-text

Peripheral mononuclear leucocyte beta adrenoceptors and non-specific bronchial responsiveness to methacholine in young and elderly normal subjects and asthmatic patients.

Thorax ◽

10.1136/thx.49.1.26 ◽

1994 ◽

Vol 49 (1) ◽

pp. 26-32 ◽

Cited By ~ 25

Author(s):

M J Connolly ◽

J J Crowley ◽

C P Nielson ◽

N B Charan ◽

R E Vestal

Keyword(s):

Normal Subjects ◽

Bronchial Responsiveness ◽

Beta Adrenoceptors ◽

Asthmatic Patients ◽

Mononuclear Leucocyte

Download Full-text

Seasonal Variability of Non-Specific Bronchial Responsiveness in Asthmatic Patients with Allergy to House Dust Mites

Allergy and Asthma Proceedings ◽

10.2500/108854101778249221 ◽

2001 ◽

Vol 22 (1) ◽

pp. 5-9 ◽

Cited By ~ 26

Author(s):

G. Riccioni ◽

F. Di Stefano ◽

M. De Benedictis ◽

N. Verna ◽

E. Cavallucci ◽

...

Keyword(s):

House Dust ◽

Seasonal Variability ◽

House Dust Mites ◽

Dust Mites ◽

Bronchial Responsiveness ◽

Asthmatic Patients

Download Full-text

Is the increase in bronchial responsiveness or FEV1 shortly after cessation ofβ2 -agonists reflecting a real deterioration of the disease in allergic asthmatic patients? A comparison between short-acting and long-acting β2-agonists

Respiratory Medicine ◽

10.1053/rmed.2001.1243 ◽

2002 ◽

Vol 96 (3) ◽

pp. 155-162 ◽

Cited By ~ 14

Author(s):

C.P. VAN SCHAYCK ◽

S.G.M. CLOOSTERMAN ◽

I.D. BIJL-HOFLAND ◽

H. VAN DEN HOOGEN ◽

H.Th.M. FOLGERING ◽

...

Keyword(s):

Bronchial Responsiveness ◽

Short Acting ◽

Asthmatic Patients ◽

Allergic Asthmatic ◽

Long Acting ◽

Β2 Agonists

Download Full-text

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100143390 ◽

1986 ◽

Vol 44 ◽

pp. 354-355

Author(s):

Kate W. Sjoerdsma ◽

W. James Metzger

Keyword(s):

Allergic Rhinitis ◽

Bronchoalveolar Lavage ◽

Allergic Asthma ◽

Skin Test ◽

Positive Skin Test ◽

Positive Skin ◽

Human Eosinophil ◽

Asthmatic Patients ◽

Allergic Asthmatic ◽

History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

Download Full-text