Increased Renal Net Acid Excretion in Prematures below 1,600 g Body Weight Compared with Prematures and Small-for-Date Newborns above 2,100 g on Alimentation with a Commercial Preterm Formula

Neonatology ◽  
1994 ◽  
Vol 66 (1) ◽  
pp. 10-15 ◽  
Author(s):  
H. Kalhoff ◽  
B. Wiese ◽  
C. Kunz ◽  
L. Diekmann ◽  
G.J. Stock ◽  
...  
Keyword(s):  
Body Weight ◽  
Acid Excretion ◽  
Renal Net Acid Excretion ◽  
Preterm Formula ◽  
Net Acid Excretion

Comparison of estimated renal net acid excretion from dietary intake and body size with urine pH

2003 ◽  
Vol 103 (8) ◽  
pp. 1001-1007 ◽  
Author(s):  
Dominique S. Michaud ◽  
Richard P. Troiano ◽  
Amy F. Subar ◽  
Shirley Runswick ◽  
Sheila Bingham ◽  
...  
Keyword(s):  
Body Size ◽  
Dietary Intake ◽  
Acid Excretion ◽  
Urine Ph ◽  
Renal Net Acid Excretion ◽  
Net Acid Excretion

Bone buffering of acid and base in humans

2003 ◽  
Vol 285 (5) ◽  
pp. F811-F832 ◽  
Author(s):  
Jacob Lemann ◽  
David A. Bushinsky ◽  
L. Lee Hamm
Keyword(s):  
Acid Production ◽  
Positive Charge ◽  
Acid Excretion ◽  
Charge Balance ◽  
Crystal Surfaces ◽  
Renal Net Acid Excretion ◽  
Positive Formula ◽  
Acid And Base ◽  
Relationship Of ◽  
Net Acid Excretion

The sources and rates of metabolic acid production in relation to renal net acid excretion and thus acid balance in humans have remained controversial. The techniques and possible errors in these measurements are reviewed, as is the relationship of charge balance to acid balance. The results demonstrate that when acid production is experimentally increased among healthy subjects, renal net acid excretion does not increase as much as acid production so that acid balances become positive. These positive imbalances are accompanied by equivalently negative charge balances that are the result of bone buffering of retained H+ and loss of bone Ca2+ into the urine. The data also demonstrate that when acid production is experimentally reduced during the administration of KHCO3, renal net acid excretion does not decrease as much as the decrease in acid production so that acid balances become negative, or, in opposite terms, there are equivalently positive [Formula: see text] balances. Equivalently positive K+ and Ca2+ balances, and thus positive charge balances, accompany these negative acid imbalances. Similarly, positive Na+ balances, and thus positive charge balances, accompany these negative acid balances during the administration of NaHCO3. These charge balances are likely the result of the adsorption of [Formula: see text] onto the crystal surfaces of bone mineral. There do not appear to be significant errors in the measurements.

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