Determination of AL01576 Concentration in Rat Lenses and Plasma by Bioassay for Aldose Reductase Activity Measurements

1989 ◽  
Vol 21 (4) ◽  
pp. 285-291 ◽  
Author(s):  
Otto Hockwin ◽  
Peter Müller ◽  
Jan Krolczyk ◽  
Bette A. McCue ◽  
Philip R. Mayer
Keyword(s):  
Aldose Reductase ◽  
Reductase Activity ◽  
Activity Measurements

scholarly journals Reverse Docking, Molecular Docking, Absorption, Distribution, and Toxicity Prediction of Artemisinin as an Anti-diabetic Candidate

Molekul ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. 88
Author(s):  
Ruswanto Ruswanto ◽  
Richa Mardianingrum ◽  
Siswandono Siswandono ◽  
Dini Kesuma
Keyword(s):  
Molecular Docking ◽  
Aldose Reductase ◽  
Glucose Concentration ◽  
In Silico ◽  
Reductase Activity ◽  
Polyol Pathway ◽  
Toxicity Prediction ◽  
In Silico Studies

Aldose reductase is an enzyme that catalyzes one of the steps in the sorbitol (polyol) pathway that is responsible for fructose formation from glucose. In diabetes, aldose reductase activity increases as the glucose concentration increases. The purpose of this research was to identify and develop the use of artemisinin as an anti-diabetic candidate through in silico studies, including reverse docking, receptor analysis, molecular docking, drug scan, absorption, and distributions and toxicity prediction of artemisinin. Based on the results, we conclude that artemisinin can be used as an anti-diabetic candidate through inhibition of aldose reductase

scholarly journals Bestimmung von Komplexen in Alkalichloroaluminat-Schmelzen aus Aktivitätsmessungen / Determination of Complexes in Alkalichloroaluminate-Melts from Activity Measurements

1973 ◽  
Vol 28 (11) ◽  
pp. 1847-1853 ◽  
Author(s):  
K. Schulze ◽  
D. Steinle ◽  
H. Hoff
Keyword(s):  
Equimolar Composition ◽  
Activity Measurements ◽  
Steep Decrease

The activity of aluminiumchloride in NaCl-, RbCl-, CsCl-containing electrolytes has been measured by the formation cell Al(s)/AlCl3-MeCl(1)/Cl2(g)/C. The EMF depends strongly on the ratio of AlCl3: MeCl and is characterized by a steep decrease of the equimolar composition. Accounting for three coupled equilibria between the 5 species Al2Cl7−, Al2Cl6, AlCl4−, Al3+, Cl− the activity as a function of concentration can be calculated very precisely. The distribution of the aluminiumchlorocomplexes is discussed for varying melt compositions.

Sign in / Sign up

Export Citation Format

Share Document