Perforating Crohn's Disease: Conservative and Surgical Treatment

2013 ◽  
Vol 31 (2) ◽  
pp. 218-221 ◽  
Author(s):  
Gianluca M. Sampietro ◽  
Silvia Casiraghi ◽  
Diego Foschi
2021 ◽  
Vol 100 (6) ◽  
pp. 78-85
Author(s):  
A.S. Bekin ◽  
◽  
E.Yu. Dyakonova ◽  
A.N. Surkov ◽  
A.P. Fisenko ◽  
...  

Crohn's disease (CD) is chronic recurrent bowel disease of unknown etiology, characterized by segmental transmural granulomatous inflammation, mainly with the development of local and systemic complications. Despite the active development of conservative therapy methods, the number of drug-resistant forms of CD and complications of the disease requiring surgical treatment continues to increase. The article reflects modern scientific ideas about the methods of diagnosis, conservative and surgical treatment of CD in children.


2018 ◽  
Vol 20 (1) ◽  
pp. 111-116
Author(s):  
I A Solovev ◽  
A M Pershko ◽  
D P Kurilo ◽  
M V Vasilchenko ◽  
E S Silchenko ◽  
...  

Possibilities and options of surgical treatment of complications of Crohn’s disease in the general surgical hospital are considered. Patients underwent various surgical interventions: ileum resection with «side-to-side» anastomosis (4 patients), resection of ileocecal department with the formation of ileoascendoanastomosis (2 patients), total coloproctectomy with the formation of ileostomy (2 patients), right-sided hemicolectomy (1 patient), obstructive resection of transverse colon (1 patient), obstructive resection of sigmoid colon (2 patients). Postoperative complications developed in 3 patients (25%), among them: postoperative wound suppuration - 2, dehiscence of anastomosis in 1 patient, which led to the formation of internal intestinal fistula and death. It was found that with limited lesions of colon in Crohn’s disease (less than a third of the colon) can be limited to resection of the affected segment with formation of intestinal anastomosis in the limits of healthy tissues. In the presence of lesions in the ascending department of colon proximal border of resection should be at the level of middle colic vessels with preservation of the latter. In long Crohn’s disease of colon with severe clinical manifestations of the operation of choice is a subtotal resection of colon with the imposition of single-barrel ileostomy. Surgical treatment of complicated forms of Crohn’s disease is in all cases performed in surgical profile hospitals, taking patients by ambulance. Most often, patients have delayed indications for operations, which gives the opportunity to carry out a comprehensive preoperative preparation. In all cases, complications of Crohn’s disease requires an individual approach, which combines conservative and surgical treatment. Surgical intervention is determined by the shape and characteristics of the course of complications of Crohn’s disease.


2008 ◽  
Vol 149 (11) ◽  
pp. 505-508 ◽  
Author(s):  
Péter Lukovich ◽  
András Papp ◽  
Péter Fuszek ◽  
Tibor Glasz ◽  
Hajnalka Győrffy ◽  
...  

A duodenumra lokalizált Crohn-betegség az összes Crohn-betegség kb. 0,5–4%-át teszi ki. Leggyakoribb tünete a gyomorürülési zavar és a jelentős fogyás. Az endoszkópos biopszia eredménye gyakran bizonytalan, ami megnehezíti az egyéb benignus szűkületektől való elkülönítését. A műtétet igénylő megbetegedés kezelése tekintetében a betegséggel foglalkozó európai konszenzusos nyilatkozat sem ad pontos irányelveket. Beteganyag: Eredménytelen konzervatív kezelés miatt a Semmelweis Egyetem I. Sebészeti Klinikáján 2002–2007 között három betegnél a gyomorürülési panasz megoldására műtétre volt szükség. Mindegyik betegnek a műtét előtt jelentős súlyvesztése (13–30 kg) volt. Két esetben sikerült a gyulladt bélszakasz eltávolítása a duodenum parciális reszekciójával, és az emésztőtraktus Billroth-II. szerint végzett rekonstrukciójával, egy esetben a leszálló duodenum érintettsége miatt csak bypassműtétre (gastro-jejunostomia) nyílt lehetőség. Eredmények: A betegek a műtét óta eltelt 45/24/9 hónap óta panaszmentesek, műtét előtti súlyukat visszanyerték. Sem korai, sem késői szövődményt nem észleltünk. Következtetések: A konzervatív kezelésre tartósan nem reagáló, szűkületet okozó duodenalis Crohn-betegség műtéti javallatot képez, azonban a fennálló malnutritio a műtét előtt kezelést igényel. A műtét típusa előre nem tervezhető, a kellően előkészített patkóbél-Crohn-beteg gyógyhajlama nem rosszabb, mint egyéb lokalizációjú sorstársaié.


2016 ◽  
pp. 131-150
Author(s):  
Hiroki Ikeuchi ◽  
Motoi Uchino ◽  
Toshihiro Bando ◽  
Kei Hirose ◽  
Nobuyuki Hida ◽  
...  

2019 ◽  
Vol 4 (1) ◽  
pp. 13
Author(s):  
Zhen-Yi Wang ◽  
Dan Gan ◽  
Wei Jin ◽  
Ying Li ◽  
Chang-Peng Han

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S427-S428
Author(s):  
S D'Ugo ◽  
F Romano ◽  
G Bagaglini ◽  
L Fazzolari ◽  
B Sensi ◽  
...  

Author(s):  

Abstract Aim The different surgical options for patients with colonic Crohn’s disease (CD) include segmental colectomy, subtotal colectomy or proctocolectomy with end ileostomy. We present a national, multicentre study, promoted by the Italian Society of Colorectal Surgery with the aim to collect benchmark data and national variations on multidisciplinary management and postoperative outcomes of patients undergoing surgery for colonic CD. Methods All adult patients having elective surgery for colonic CD from June 2018 to May 2019 were eligible for participation in this retrospective study. The primary outcome measure was postoperative morbidity within 30 days of surgery. Results One hundred twenty-two patients were included: 55 subtotal colectomy, 30 segmental colectomy, 25 proctectomy and 12 proctocolectomy. Eighty-six patients (70.4%) were discussed at the inflammatory bowel disease (IBD) multidisciplinary team meeting (MDT) prior to surgery. This ranged from 76.6% for segmental colectomy to 60% for subtotal colectomy, 66.6% for proctocolectomy and 48% for proctectomy. The proportion of patients counselled by a stoma nurse preoperatively was 50%. Laparoscopy was associated with reduced postoperative morbidity (p = 0.017) and shorter length of hospital stay (p < 0.001), whilst pre-operative anti-TNF was associated with Dindo-Clavien ≥ 3 complications (p = 0.023) and longer in-hospital stay (p = 0.007). The main procedure performed (segmental colectomy, subtotal colectomy, proctocolectomy or proctectomy) was not associated with postoperative morbidity (p = 0.626). Conclusions Surgery for colonic CD has a high rate of postoperative complications. Almost a third of the patients were not preoperatively discussed at the IBD MDT, whilst the use of minimally invasive surgery for surgical treatment of colonic CD ranges from 40 to 66%.


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