Inclusion of Attentional Networks in the Pre-Surgical Neuroimaging Assessment of a Large Deep Hemispheric Cavernous Malformation: An fMRI Case Report

Background and Importance: Functional magnetic resonance imaging (fMRI) is a noninvasive and reliable tool for mapping eloquent cortex in patients prior to brain surgery. Ensuring intact perceptual and cognitive processing is a key goal for neurosurgeons, and recent research has indicated the value of including attentional network processing in pre-surgical fMRI in order to help preserve such abilities, including reading, after surgery. Clinical Presentation: We report a 42-year-old patient with a large cavernous malformation, near the left basal ganglia. The lesion measured 3.8 × 1.7 × 1.8 cm. In consultation with the patient and the multidisciplinary cerebrovascular team, the decision was made to offer the patient surgical resection. The surgical resection involved planned access via the left superior parietal lobule using stereotactic location. The patient declined an awake craniotomy; therefore, direct electrocortical stimulation (ECS) could not be used for intraoperative language localization in this case. Pre-surgical planning included fMRI localization of language, motor, sensory, and attentional processing. The key finding was that both reading and attention-processing tasks revealed consistent activation of the left superior parietal lobule, part of the attentional control network, and the site of the planned surgical access. Given this information, surgical access was adjusted to avoid interference with the attentional control network. The lesion was removed via the left inferior parietal lobule. The patient had no new neurologic deficits postoperatively but did develop mild neuropathic pain in the left hand. Conclusion: This case report supports recent research that indicates the value of including fMRI maps of attentional tasks along with traditional language-processing tasks in preoperative planning in patients undergoing neurosurgery procedures.

Download Full-text

Cognitive Processing of Miscommunication in Interactive Listening: An Evaluation of Listener Indecision and Cognitive Effort

Journal of Speech Language and Hearing Research ◽

10.1044/2020_jslhr-20-00128 ◽

2021 ◽

pp. 1-17

Author(s):

Jennifer M. Roche ◽

Arkady Zgonnikov ◽

Laura M. Morett

Keyword(s):

Decision Making ◽

Cognitive Processing ◽

Language Processing ◽

Cognitive Effort ◽

Mouse Tracking ◽

Computer Mouse ◽

Decision Making Processes ◽

Computer Mouse Tracking ◽

Listening Task ◽

Processing Effort

Purpose The purpose of the current study was to evaluate the social and cognitive underpinnings of miscommunication during an interactive listening task. Method An eye and computer mouse–tracking visual-world paradigm was used to investigate how a listener's cognitive effort (local and global) and decision-making processes were affected by a speaker's use of ambiguity that led to a miscommunication. Results Experiments 1 and 2 found that an environmental cue that made a miscommunication more or less salient impacted listener language processing effort (eye-tracking). Experiment 2 also indicated that listeners may develop different processing heuristics dependent upon the speaker's use of ambiguity that led to a miscommunication, exerting a significant impact on cognition and decision making. We also found that perspective-taking effort and decision-making complexity metrics (computer mouse tracking) predict language processing effort, indicating that instances of miscommunication produced cognitive consequences of indecision, thinking, and cognitive pull. Conclusion Together, these results indicate that listeners behave both reciprocally and adaptively when miscommunications occur, but the way they respond is largely dependent upon the type of ambiguity and how often it is produced by the speaker.

Download Full-text

Fabricating a Partial Denture Obturator for the rehabilitation of Maxillectomy Patient - A Case Report

Update Dental College Journal ◽

10.3329/updcj.v1i2.13983 ◽

2013 ◽

Vol 1 (2) ◽

pp. 25-28

Author(s):

Md Ali Afzal Khan ◽

Md Nazmul Hasan ◽

Newaz Mohsina ◽

Aleya Begum

Keyword(s):

Case Report ◽

Speech Production ◽

Surgical Resection ◽

Partial Denture ◽

Functional Capabilities ◽

Palatal Obturator ◽

Maxillary Defects ◽

Normal Speech

Obturator prostheses are considered to be the preferred choice for the restoration of maxillary defects. Patients with palatal insufficiency, speech and deglutition becomes impaired, thereby requiring prosthodontic rehabilitation. The prosthodontic rehabilitation of patients with acquired defects of the maxilla after surgical resection is the complete responsibility of a maxillofacial prosthodontist. He has to recreate an artificial barrier between the cavities and thus restore the functional capabilities of speech, mastication and swallowing. Palatal obturator is the only substitute which covers the defect and contributes to normal speech production. It eliminates hypernasality and improves the communication.DOI: http://dx.doi.org/10.3329/updcj.v1i2.13983 Update Dent. Coll. j. 2011: 1(2): 25-28

Download Full-text

A Case Report and Overview of Familial Cerebral Cavernous Malformation Pathogenesis in an Adult Patient

JHN Journal ◽

10.29046/jhnj.013.2.003 ◽

2018 ◽

Vol 13 (2) ◽

Author(s):

Manu Arul ◽

Omaditya Khanna ◽

Michael Gooch

Keyword(s):

Case Report ◽

Adult Patient ◽

Cavernous Malformation ◽

Cerebral Cavernous Malformation ◽

Familial Cerebral Cavernous Malformation

Download Full-text

The Opposition of Surprisal and Semantic Similarity in the Prediction of Language Processing: Evidence from Eye-tracking Data

10.31234/osf.io/zypk9 ◽

2020 ◽

Author(s):

Kun Sun

Keyword(s):

Eye Tracking ◽

Semantic Similarity ◽

Cognitive Processing ◽

Language Processing ◽

Language Comprehension ◽

Word Processing ◽

Reading Time ◽

Computational Models ◽

Tracking Data ◽

Dynamic Approach

Expectations or predictions about upcoming content play an important role during language comprehension and processing. One important aspect of recent studies of language comprehension and processing concerns the estimation of the upcoming words in a sentence or discourse. Many studies have used eye-tracking data to explore computational and cognitive models for contextual word predictions and word processing. Eye-tracking data has previously been widely explored with a view to investigating the factors that influence word prediction. However, these studies are problematic on several levels, including the stimuli, corpora, statistical tools they applied. Although various computational models have been proposed for simulating contextual word predictions, past studies usually preferred to use a single computational model. The disadvantage of this is that it often cannot give an adequate account of cognitive processing in language comprehension. To avoid these problems, this study draws upon a massive natural and coherent discourse as stimuli in collecting the data on reading time. This study trains two state-of-art computational models (surprisal and semantic (dis)similarity from word vectors by linear discriminative learning (LDL)), measuring knowledge of both the syntagmatic and paradigmatic structure of language. We develop a `dynamic approach' to compute semantic (dis)similarity. It is the first time that these two computational models have been merged. Models are evaluated using advanced statistical methods. Meanwhile, in order to test the efficiency of our approach, one recently developed cosine method of computing semantic (dis)similarity based on word vectors data adopted is used to compare with our `dynamic' approach. The two computational and fixed-effect statistical models can be used to cross-verify the findings, thus ensuring that the result is reliable. All results support that surprisal and semantic similarity are opposed in the prediction of the reading time of words although both can make good predictions. Additionally, our `dynamic' approach performs better than the popular cosine method. The findings of this study are therefore of significance with regard to acquiring a better understanding how humans process words in a real-world context and how they make predictions in language cognition and processing.

Download Full-text

Anesthesia in Carvajal syndrome; the first case report

Anaesthesia, Pain & Intensive Care ◽

10.35975/apic.v24i1.1233 ◽

2020 ◽

Vol 24 (1) ◽

pp. 105-107

Author(s):

Sedighe Shahhosseini ◽

Reza Aminnejad ◽

Amir Shafa ◽

Mehrdad Memarzade

Keyword(s):

Intensive Care ◽

Case Report ◽

Surgical Resection ◽

Genetic Disorder ◽

Anesthetic Technique ◽

Close Monitoring ◽

Anesthesia Management ◽

Rare Genetic Disorder ◽

First Case ◽

Anesthetic Considerations

Carvajal syndrome is a rare genetic disorder. Patients reporting for surgery pose some difficulties in anesthesia management. In this case report we present the case of a 12-year-old boy, who was a known case of Carvajal syndrome, referred for surgical resection of perianal condyloma. Close monitoring of hemodynamic status is the mainstay of anesthetic considerations in such patients. As in any other challenging scenario, it should be kept in mind that ‘there is no safest anesthetic agent, nor the safest anesthetic technique; there is only the safest anesthesiologist’. Citation: Shahhosseini S, Aminnejad R, Shafa A, Memarzadeh M. Anesthesia in Carvajal syndrome; the first case report. Anaesth pain intensive care 2020;24(1):___ DOI: https://doi.org/10.35975/apic.v24i1.

Download Full-text