scholarly journals A Case of Basal Cell Carcinoma with Outer Hair Follicle Sheath Differentiation

2015 ◽  
Vol 7 (3) ◽  
pp. 352-357
Author(s):  
Masazumi Onishi ◽  
Kazuhiro Takahashi ◽  
Fumihiko Maeda ◽  
Toshihide Akasaka
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Hair Follicle ◽  
Basal Cell ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Old Japanese ◽  
Peripheral Palisading ◽  
Follicle Differentiation ◽  
Proliferating Trichilemmal Tumor

A 70-year-old Japanese man presented at our hospital with an asymptomatic, blackish, irregularly shaped plaque with a gray nodule in the periphery on his left lower leg. The lesion had been present for 10 years and had recently enlarged, associated with bleeding. Histopathologically, the tumor consisted of three distinct parts: The first part showed massive aggregation of basophilic basaloid cells with peripheral palisading and abundant melanin granules, and was diagnosed as solid-type basal cell carcinoma. The second part showed aggregation of clear cells with squamous eddies, and was diagnosed as proliferating trichilemmal tumor. The third part showed reticular aggregation of basaloid cells with infundibular cysts in the papillary dermis, and was diagnosed as infundibulocystic basal cell carcinoma. We diagnosed this tumor as basal cell carcinoma with various forms of hair follicle differentiation, including differentiation into the outer root sheath.

scholarly journals Human basal cell carcinoma: the induction of anagen hair follicle differentiation

2020 ◽  
Vol 45 (3) ◽  
pp. 309-317
Author(s):  
H. J. Morgan ◽  
A. Benketah ◽  
C. Olivero ◽  
E. Rees ◽  
S. Ziaj ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Hair Follicle ◽  
Basal Cell ◽  
Anagen Hair ◽  
Follicle Differentiation ◽  
Human Basal Cell Carcinoma

Hair follicle differentiation‐specific keratin expression in human basal cell carcinoma

2019 ◽  
Vol 45 (4) ◽  
pp. 417-425
Author(s):  
H. J. Morgan ◽  
A. Benketah ◽  
C. Olivero ◽  
E. Rees ◽  
S. Ziaj ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Hair Follicle ◽  
Basal Cell ◽  
Keratin Expression ◽  
Follicle Differentiation ◽  
Human Basal Cell Carcinoma

BOWENOID BASAL CELL CARCINOMA OF THE THUMB: A CASE REPORT AND REVIEW OF THE LITERATURE

Hand Surgery ◽  
2002 ◽  
Vol 07 (02) ◽  
pp. 295-298 ◽  
Author(s):  
M. Galeano ◽  
M. Colonna ◽  
M. Lentini ◽  
F. Stagno D'Alcontres
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Basal Layer ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Skin Malignancy ◽  
Root Sheath ◽  
Common Skin

Basal cell carcinoma (BCC) is the most common skin malignancy arising from cells of the basal layer of the epithelium or from the external root sheath of the hair follicle. BCC of the digit is a rare entity. The article presents one such case of bowenoid BCC of the thumb which required amputation at the MP joint.

scholarly journals Molecular Conversations and the Development of the Hair Follicle and Basal Cell Carcinoma

2010 ◽  
Vol 3 (10) ◽  
pp. 1217-1221 ◽  
Author(s):  
Pamela Jo Harris ◽  
Naoko Takebe ◽  
S. Percy Ivy
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Hair Follicle ◽  
Basal Cell

scholarly journals Trichoepithelioma of thigh. Third reported case

2015 ◽  
Vol 1 (3) ◽  
pp. 187
Author(s):  
Sandesh Deolekar ◽  
Nisha Mandhane ◽  
Sharique Ansari ◽  
Tanveer Shaikh ◽  
Sangram Karandikar
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Hair Follicle ◽  
Malignant Transformation ◽  
Basal Cell ◽  
Benign Tumor ◽  
Wide Excision ◽  
Basal Cells ◽  
Close Resemblance ◽  
Adnexal Tumors

<p class="abstract"><span lang="EN-US">Trichoepithelioma a small benign tumor derived from basal cells in the hair follicle. A trichoepithelioma can undergo malignant transformation into the basal cell carcinoma. The recognition of trichoepithelioma is important because of its close resemblance to basal cell carcinoma and other skin adnexal tumors, both clinically and histopathologically. Here we present case of 40 year old male presenting with painless swelling in right thigh. Wide excision of swelling was done and sent for histopathology which showed the swelling to be trichoepithelioma.</span></p>

scholarly journals Spontaneous Regression of Annular Basal Cell Carcinoma: A Case Report

2019 ◽  
Vol 11 (2) ◽  
pp. 145-149
Author(s):  
Usho Go ◽  
Kazunori Miyata ◽  
Masaru Fujita ◽  
Takashi Ohide ◽  
Tsuyoshi Mitsuishi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Spontaneous Regression ◽  
Histopathological Examination ◽  
Sweat Glands ◽  
Temporal Region ◽  
Japanese Male ◽  
Old Japanese ◽  
The Right

We herein present a case of annular basal cell carcinoma (BCC) with spontaneous regression on the right temporal region of a 56-year-old Japanese male. Histopathological examination revealed that the central section had no tumor cells. The sweat glands, follicles, and other cutaneous appendages were also absent. This pattern of spontaneous regression is quite uncommon, and understanding the histopathology may be important for future approaches to BCC.

scholarly journals Lesions Mimicking Melanoma at Dermoscopy Confirmed Basal Cell Carcinoma: Evaluation with Reflectance Confocal Microscopy

Dermatology ◽  
2018 ◽  
Vol 235 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Francesca Peccerillo ◽  
Victor Desmond Mandel ◽  
Francesca Di Tullio ◽  
Silvana Ciardo ◽  
Johanna Chester ◽  
...  
Keyword(s):  
Cluster Analysis ◽  
Confocal Microscopy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Hierarchical Cluster ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions ◽  
Peripheral Palisading

Background: Atypical basal cell carcinoma (BCC), characterized by equivocal dermoscopic features typical of malignant melanoma (MM), can be difficult to diagnose. Reflectance confocal microscopy (RCM) enables in vivo imaging at nearly histological resolution. Objectives: To evaluate with RCM atypical melanocytic lesions identified in dermoscopy, according to common RCM criteria for the differential diagnosis of BCC, and to identify representative RCM parameters for superficial (sBCCs) and nonsuperficial (nsBCCs) basal cell carcinomas (BCCs). Methods: A retrospective analysis of consecutive patients evaluated with RCM, selecting excised lesions classified at dermoscopy with ≥1 score from the re visited 7-point checklist, mimicking melanoma, registered between 2010 and 2016. Cluster analysis identified BCC subclassifications. Results: Of 178 atypical lesions, 34 lesions were diagnosed as BCCs with RCM. Lesions were confirmed BCCs with histopathology. Dermoscopic features included atypical network (55.9%) and regression structures (35.5%) associated with sBCCs, and an atypical vascular pattern (58.8%) and irregular blotches (58.8%) with nsBCCs. Hierarchical cluster analysis identified 2 clusters: cluster 1 (100% sBCCs) was characterized by the presence of cords connected to the epidermis (90%, p < 0.001), tumor islands located in the epidermis (100%, p < 0.001), smaller vascular diameter (100%, p < 0.001) and solar elastosis (90%, p = 0.017), and cluster 2 (nsBCCs 85%) was defined by the dermic location of tumor islands (87.5%, p < 0.001) with branch-like structures (70.8%, p = 0.007) and surrounding collagen (83.3%, p = 0.012), peripheral palisading (83.3%, p = 0.012) and coiled vascular morphology (79.2%, p < 0.001) with a larger vascular diameter (50%, p < 0.001). Conclusions: RCM is able to diagnose BCCs mimicking melanoma at dermoscopy and seems able to identify sBCCs and nsBCCs.

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