scholarly journals Spontaneous Regression of Annular Basal Cell Carcinoma: A Case Report

2019 ◽  
Vol 11 (2) ◽  
pp. 145-149
Author(s):  
Usho Go ◽  
Kazunori Miyata ◽  
Masaru Fujita ◽  
Takashi Ohide ◽  
Tsuyoshi Mitsuishi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Spontaneous Regression ◽  
Histopathological Examination ◽  
Sweat Glands ◽  
Temporal Region ◽  
Japanese Male ◽  
Old Japanese ◽  
The Right

We herein present a case of annular basal cell carcinoma (BCC) with spontaneous regression on the right temporal region of a 56-year-old Japanese male. Histopathological examination revealed that the central section had no tumor cells. The sweat glands, follicles, and other cutaneous appendages were also absent. This pattern of spontaneous regression is quite uncommon, and understanding the histopathology may be important for future approaches to BCC.

scholarly journals Pigmented Paraaxillary Located "Complex" Basal Cell Carcinoma Imitating clinically irritated Melanocytic Lesion - Succesfull Surgical Approach in Bulgarian Patient

2017 ◽  
Vol 5 (4) ◽  
pp. 497-500
Author(s):  
Cristiana Voicu ◽  
Mara Mihai ◽  
Mihai Lupu ◽  
James W. Patterson ◽  
Nely Koleva ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Melanocytic Lesion ◽  
Complete Surgical Excision ◽  
Axillary Region ◽  
The Right ◽  
Clinical Subtype

BACKGROUND: Basal cell carcinoma (BCC) is the most frequently encountered neoplasm worldwide. While nodular BCC is the most frequent clinical subtype, other forms of BCC, such as superficial, cystic, morpheiform, infiltrative, and pigmented may also be encountered.CASE PRESENTATION: We present the case of a 67-year-old male with a relatively well-defined infiltrative, pigmented plaque with multiple colours and peripheral growth situated in the right axillary region. The histopathologic examination performed after complete surgical excision of the tumour revealed a complex pigmented BCC with macronodular, fibroepithelioma-like, cystic, focally infiltrative and basosquamous features.CONCLUSION: Uncommon locations of BCCs in sun-protected areas such as the axillary region require a higher degree of suspicion for diagnosis. The complex histology of the presented case, including subtypes with differing biologic attributes, emphasises the importance of histopathological examination in the diagnosis and therapeutic management of BCC.

scholarly journals Large Basal Cell Carcinoma Defect Closure on The Lateral Cheek Using Multiple Advancement Flaps

2021 ◽  
pp. 1-7
Author(s):  
Siswanto Wahab ◽  
Khairuddin Djawad
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Skin Flap ◽  
Reconstruction Procedure ◽  
The Face ◽  
Advancement Flaps ◽  
Substantial Morbidity

Basal cell carcinoma (BCC) is the most common type of nonmelanoma skin cancer (NMSC). It grows slowly and very rarely metastasizes but can cause substantial morbidity due to its tendency to relapse and locally invasive nature, especially when located on the face. Excision surgery is still the gold standard treatment for primary BCC and is usually followed by reconstruction procedure. Skin flap techniques vary widely, one of which is flap advancement technique. The main benefit of flap advancement technique is the ability to hide the excision line, thus resulting in an aesthetically sound outcome. We report a case of 72-year-old female with hyperpigmented plaque brownish lump on the left lateral cheek. A diagnosis of igmented basal cell carcinoma had been confirmed through histopathological examination. The patient was treated with wide excision surgery and the defect was closed by multiple advancement flaps. Follow-up after three months showed excellent cosmetic and functional outcome.

Basal Cell Carcinoma on the Right Hallux

2003 ◽  
Vol 30 (3) ◽  
pp. 250-251 ◽  
Author(s):  
Kiyomi Matsushita ◽  
Akira Kawada ◽  
Yoshinori Aragane ◽  
Tadashi Tezuka
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
The Right

scholarly journals Concurrent primary and secondary myiasis on basal cell carcinoma

2012 ◽  
Vol 87 (2) ◽  
pp. 292-295 ◽  
Author(s):  
Adriana Andrade Raposo ◽  
Antônio Pedro Mendes Schettini ◽  
Cesare Massone
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histopathological Examination ◽  
Traumatic Injury ◽  
Skin Condition ◽  
Healthy Patient ◽  
Dorsal Region ◽  
Skin Cancers ◽  
Fly Larvae

Myiasis is a disease caused by infestation of fly larvae in human and other vertebrate tissues. It is a skin condition common in tropical and subtropical countries and its predisposing factors are: chronic diseases, immunodeficiency, poor hygiene, senility, psychiatric disorders, skin cancers and ulcerated mucosae. We report the case of a healthy patient who after traumatic injury of a preexisting lesion showed a tumor on the dorsal region parasitized by fly larvae. The histopathological examination performed for the diagnosis of skin neoplasm surprisingly revealed the presence of a partially degenerated larva with characteristics of Dermatobia hominis, suggesting an association of primary and secondary myiasis on basal cell carcinoma.

scholarly journals Basal Cell Carcinoma with Disseminated Bone Metastization: An Unusual Outcome of the Most Common Malignancy

2021 ◽  
Vol 79 (3) ◽  
pp. 261-264
Author(s):  
Luísa Rolim ◽  
Bruno M. Fernandes ◽  
Carolina Carvalho ◽  
António Silva ◽  
Joana Calvão ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Survival Rates ◽  
Palliative Radiotherapy ◽  
High Morbidity ◽  
Common Skin ◽  
Metastatic Basal Cell Carcinoma ◽  
Low Incidence ◽  
The Right

Basal cell carcinoma is the most common skin cancer, with a very low incidence of metastases, associated with high morbidity and mortality. The morpheaform clinical variant is uncommon, presenting an aggressive growth pattern. Early diagnosis and new targeted therapies for metastatic disease are important to improve survival rates. We present the case of a 29-year-old patient with morpheaform basal cell carcinoma in the right genian region. Due to local recurrences, he underwent surgery and adjuvant radiotherapy. For extensive metastatic bone involvement, the patient started vismodegib and, later, pembrolizumab, and also performed palliative radiotherapy. Despite several lines of systemic therapy, the disease progressed, and the patient died after 8 years of follow-up. This case shows how crucial it is to identify risk factors for metastatic basal cell carcinoma and highlights the need to improve target therapies and tailor them to the patient’s biological profile.

scholarly journals Comparison of BCL-2 Ecpression in Periocular Basal Cell Carcinoma Aggressive and Non-Aggressive Types in Mohammad Hoesin Hospital Palembang

2018 ◽  
Vol 1 (2) ◽  
pp. 18-36
Author(s):  
Fera Yunita Rodhiaty ◽  
Ika Kartika ◽  
Ibrahim
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Malignant Tumor ◽  
Histopathological Examination ◽  
Basal Layer ◽  
Growth Patterns ◽  
Bivariate Analysis ◽  
Fisher Exact Test ◽  
Cross Sectional

Abstract Background: Basal cell carcinoma (BCC) is a malignant tumor originating from non- keratinizing cells originating from the basal layer of the epidermis. Basal cell carcinoma is the most common malignant tumor, nearly 90% of all non-melanoma skin cancers. Clinically, BCC is difficult to distinguish, final diagnosis determined based on histopathological examination of complete tumor tissue. Based on histological growth patterns, BCC is divided into two, non- aggressive type (nodular and superficial) and aggressive type (infiltration, micronodular, fibroepithelial, basoskuamosa, keratotic, adnexal differentiation). The examination technique by analyzing the proteins or genes involved is related to the aggressiveness of basal cell carcinoma. Objective: This study was conducted to determine the comparison of expression of Bcl-2 in periocular basal type aggressive and non-aggressive carcinomas in dr. Mohammad Hoesin Palembang. Methodology: A cross sectional analytic study from 26 periocular basal cell carcinoma patients in RSUP dr. Mohammad Hoesin Palembang, January 2014- June 2018. Histopathologic features were examined with hematoxylin-eosine staining and imunohistochemical were examined with Bcl-2 monoclonal antibody. Data were analyzed by bivariate analysis, using chi-square test and fisher exact test. Results: Positive Bcl-2 expression was more common in periocular basal cell carcinoma (93.8%) than aggressive (50%), and nodular type (93.8%) compared to other types of histological differentiation. Positive Bcl-2 expression was also higher in female patients (90.9%) than males (66.7%). There is a significant relationship between expression of Bcl-2 and growth patterns, differentiation of cell histology and also sex of patients with basal cell carcinoma. Conclusion: In this study, there was a significant correlation between expression of Bcl-2 and aggressive and non-aggressive periocular basal cell carcinoma in RSUP dr. Mohammad Hoesin Palembang.

Aggressive Basal Cell Carcinoma of the Temporal Region in a Patient with Gorlin-Goltz Syndrome

2000 ◽  
Vol 44 (4) ◽  
pp. 429-434 ◽  
Author(s):  
José M. Lasso ◽  
Emilio García-Tutor ◽  
Antonio Bazán
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Temporal Region ◽  
Goltz Syndrome

scholarly journals A A Rare Case of a Metastatic Basal Cell Carcinoma

2020 ◽  
Vol 2 (5) ◽  
Author(s):  
Hiba Chaudhry ◽  
Dimitrios Doumpiotis
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Incidence Rate ◽  
Basal Cell ◽  
Literature Search ◽  
Primary Tumour ◽  
Sun Exposure ◽  
Metastatic Basal Cell Carcinoma ◽  
Radiation Genetic ◽  
The Right

Background: Basal cell carcinomas are malignant slow-growing neoplasms of the epidermal layer of the skin. They are the most common form of skin cancer, accounting for 80% of non-melanoma skin cancers. Metastasis is rare with an incidence rate of 0.0028 to 0.55%. We report a case of an 83 year old male presenting with basal cell carcinoma (BCC) of the right cheek. The tumour was completely excised with close margins. The patient was closely monitored clinically and on follow-up, a mass in the region of the right parotid was identified. Excision of the tail of the right parotid identified a tumour with similar subtype to the primary tumour excised from the cheek confirming diagnosis of metastatic BCC. Methods: A literature search was carried out inclusive of the terms identify existing data and guidelines to determine best evidence based practice. Discussion: Literature search identified aetiology of BCCs and methods of diagnosis and treatment. The search also highlighted an incidence rate of 0.0028 to 0.55% and complications associated with metastasis. The patient underwent a course of radiotherapy as surgery in this case was contraindicated due to history of excision of the parotid tail. Risk factors for developing BCCs include intermittent sun exposure, ionising radiation, genetic predisposition and immunosuppression. Metastases occurs via the lymphatic system or haematogenously. Surgery is the main form of treatment and aims to be curative.

scholarly journals Locally advanced basal cell carcinoma of the auricle and parotid region: A case report

2021 ◽  
Vol 68 (2) ◽  
pp. 94-98
Author(s):  
Srdjan Milanovic ◽  
Suzana Stojanovic-Rundic ◽  
Nikola Milosevic ◽  
Branko Dozic ◽  
Marko Dozic
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Multidisciplinary Approach ◽  
Locally Advanced ◽  
Parotid Region ◽  
Basal Cell Carcinomas ◽  
The Right ◽  
Advanced Basal Cell Carcinoma

Skin cancers are the most common malignant tumors in general. The most significant risk factor is exposure to UV radiation. They mainly occur in the head and neck region, and the majority of about 80% are basal cell carcinomas. Surgery is standard treatment of uncomplicated basal cell carcinomas, but a multidisciplinary approach is necessary in advanced cases. The case report refers to a patient with locally advanced recurrent basal cell carcinoma with primary tumor localization in the right auricle and parotid region in 2012 when primary surgery was performed. Due to the local recurrence, amputation of the right auricle and trepanation of the mastoid process was done in November 2018, and after that, radiation therapy of a recurrent tumor in the area of the trepanation cavity was applied. In the course of follow-up so far, there is good local control, without signs of toxicity. The case report points to the importance of a multidisciplinary approach and the role of radiotherapy in the treatment and control of advanced basal cell carcinoma of this region.

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