scholarly journals Small Cell Cancer of the Genitourinary Tract: A Case Report and Review of the Literature

2017 ◽  
Vol 10 (2) ◽  
pp. 489-492 ◽  
Author(s):  
Ho Man Yeung ◽  
Chetan Jeurkar ◽  
Tiffany Pompa ◽  
Michael Styler

Small cell carcinoma of the urinary tract is an extremely rare disease with very few cases reported in the literature. Its clinical course is aggressive, and the prognosis is poor. Here, we present a case of metastatic extrapulmonary small cell carcinoma of the upper urinary tract in a 74-year-old African-American male. He initially presented with gross hematuria, 20-pound weight loss, and abdominal pain for 2 months. CT imaging showed a 14.0 × 7.0 × 16.0 cm retroperitoneal mass within the left renal fossa; biopsy revealed a carcinoma which was positive for synaptophysin and chromogranin. The patient also had detectable neuroendocrine cells in his urine cytology, confirming the diagnosis of small cell carcinoma. He was treated with carboplatin and etoposide as extrapolated from the treatment of its pulmonary counterpart. Due to the rarity of urinary tract small cell carcinoma, no randomized studies exist to guide therapy or management.

1992 ◽  
Vol 78 (6) ◽  
pp. 409-413 ◽  
Author(s):  
Maurizio Amichetti ◽  
Sebastiana Boi ◽  
Gianni Fellin ◽  
Sergio Maluta ◽  
Paolo Dalla Palma ◽  
...  

Undifferentiated small cell carcinoma of the bladder is a rare but aggressive subset of urinary tract neoplasms. Analogous to small-cell carcinoma of the lung, this tumor frequently exhibits neuroendocrine differentiation. We report the 92nd and 93rd case of small cell carcinoma of the bladder reported in the literature with characteristic cytologic, histologic, histochemical, and ultrastructural features. The patients were treated initially with chemotherapy, but after a brief clinical course died for progression of disease and for myocardial infarction, respectively. The pathologic and clinical features and therapeutic options of the cases described in the literature are reviewed.


2011 ◽  
Vol 37 (5) ◽  
pp. 366-372 ◽  
Author(s):  
Adil Ouzzane ◽  
Tarek P. Ghoneim ◽  
Kazuma Udo ◽  
Marie Verhasselt-Crinquette ◽  
Philippe Puech ◽  
...  

2019 ◽  
Vol 27 ◽  
pp. 100995
Author(s):  
Veronica Rupert ◽  
Marisa M. Clifton ◽  
Brant R. Fulmer ◽  
Ryan L. Mori ◽  
Heinric Williams ◽  
...  

BMJ Open ◽  
2015 ◽  
Vol 5 (1) ◽  
pp. e006440-e006440 ◽  
Author(s):  
S. Gennatas ◽  
J. Noble ◽  
S. Stanway ◽  
R. Gunapala ◽  
R. Chowdhury ◽  
...  

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