scholarly journals Health-Related Quality of Life according to Renal Function: Results from a Nationwide Health Interview and Examination Survey

2021 ◽  
pp. 1-10
Author(s):  
Liv Faulhaber ◽  
Stefan Herget-Rosenthal ◽  
Hannes Jacobs ◽  
Falk Hoffmann
Keyword(s):  
Kidney Disease ◽  
State Of Health ◽  
General State ◽  
Health Related Quality ◽  
End Stage Kidney Disease ◽  
Related Quality ◽  
Health Related ◽  
End Stage ◽  
Physical Hrqol

<b><i>Background:</i></b> Most studies on health-related quality of life (HRQoL) in chronic kidney disease (CKD) focus on patients with end-stage kidney disease although they represent a small proportion of patients with CKD. We aimed to analyze HRQoL according to glomerular filtration rate (GFR) categories in a population-based sample of adults living in Germany. <b><i>Methods:</i></b> Data from the German health interview and examination survey conducted from 2008 to 2011 were used. Participants with valid interview and examination data aged 40–79 years were included (<i>n</i> = 5,159). Serum creatinine levels were used to calculate estimated GFR via the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. We classified kidney function in GFR categories according to the Kidney Disease Improving Global Outcomes Initiative (KDIGO) guidelines on CKD: G1 (high): ≥90 mL/min/1.73 m<sup>2</sup>, G2 (normal): 60–89 mL/min/1.73 m<sup>2</sup>, G3a (mildly decreased): 45–59 mL/min/1.73 m<sup>2</sup>, G3b (moderately decreased): 30–44 mL/min/1.73 m<sup>2</sup>, G4/5 (severely decreased/end-stage kidney disease): &#x3c;30 mL/min/1.73 m<sup>2</sup>. HRQoL was evaluated with the Short Form Health Survey (SF-36). Different multivariate linear and logistic regression models were used to analyze the association of HRQoL with GFR categories. <b><i>Results:</i></b> Overall, 5.9% had a GFR &#x3c;60 mL/min/1.73 m<sup>2</sup> (corresponding to categories G3a, G3b, and G4/5). Compared to category G2 linear regression showed a decline in physical HRQoL in categories G3a (−2.34, <i>p</i> = 0.004), G3b (−5.37, <i>p</i> = 0.009), and G4/5 (−4.82, <i>p</i> = 0.117). No decline in mental HRQoL was detected with increasing GFR categories. Categories G3a to G4/5 were significantly associated with a low perceived general state of health (G3a: odds ratio [OR] = 2.03, <i>p</i> = 0.001; G3b: OR = 3.01, <i>p</i> = 0.009; G4/5: OR = 8.70, <i>p</i> = 0.016) when compared to category G2. <b><i>Conclusion:</i></b> In a representative sample of adults living in Germany, both physical HRQoL and the perceived general state of health are already significantly reduced in category G3a.

Health-related quality of life and symptoms of conservative care versus dialysis in patients with end-stage kidney disease: a systematic review

2020 ◽  
Author(s):  
Wouter R Verberne ◽  
Iris D van den Wittenboer ◽  
Carlijn G N Voorend ◽  
Alferso C Abrahams ◽  
Marjolijn van Buren ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Older Patients ◽  
Health Related Quality ◽  
End Stage Kidney Disease ◽  
Conservative Care ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
End Stage

Abstract Background Non-dialytic conservative care (CC) has been proposed as a viable alternative to maintenance dialysis for selected older patients to treat end-stage kidney disease (ESKD). This systematic review compares both treatment pathways on health-related quality of life (HRQoL) and symptoms, which are major outcomes for patients and clinicians when deciding on preferred treatment. Methods We searched PubMed, Embase, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus and PsycINFO from inception to 1 October 2019 for studies comparing patient-reported HRQoL outcomes or symptoms between patients who chose either CC or dialysis for ESKD. Results Eleven observational cohort studies were identified comprising 1718 patients overall. There were no randomized controlled trials. Studies were susceptible to selection bias and confounding. In most studies, patients who chose CC were older and had more comorbidities and worse functional status than patients who chose dialysis. Results were broadly consistent across studies, despite considerable clinical and methodological heterogeneity. Patient-reported physical health outcomes and symptoms appeared to be worse in patients who chose CC compared with patients who chose dialysis but had not yet started, but similar compared with patients on dialysis. Mental health outcomes were similar between patients who chose CC or dialysis, including before and after dialysis start. In patients who chose dialysis, the burden of kidney disease and impact on daily life increased after dialysis start. Conclusions The available data, while heterogeneous, suggest that in selected older patients, CC has the potential to achieve similar HRQoL and symptoms compared with a dialysis pathway. High-quality prospective studies are needed to confirm these provisional findings.

scholarly journals Quality Of Life And Health Related Quality Of Life Among End-Stage Kidney Disease Patients: Methodology Assessment

2020 ◽  
Vol 6 (3) ◽  
pp. 1-11
Author(s):  
Issa Al Salmi ◽  
Keyword(s):  
Quality Of Life ◽  
Kidney Disease ◽  
Health Related Quality ◽  
End Stage Kidney Disease ◽  
Related Quality ◽  
Health Related ◽  
End Stage ◽  
The Impact

End-Stage Kidney Disease (ESKD) is a serious and irreversible condition. Understanding the impact of ESKD and its treatment on an individual's Quality of Life (QoL) is important.

scholarly journals Quality Of Life And Health-Related Quality Of Life Among End-Stage Kidney Disease Patients: Testing The Concepts And Assessing The Measures

2020 ◽  
Vol 6 (3) ◽  
pp. 1-24
Author(s):  
Issa Al Salmi ◽  
Keyword(s):  
Quality Of Life ◽  
Kidney Disease ◽  
Life Quality ◽  
Health Related Quality ◽  
End Stage Kidney Disease ◽  
Western Countries ◽  
Related Quality ◽  
Health Related ◽  
End Stage

Little is known about how patients with End-Stage Kidney Disease (ESKD) view their life quality, yet this is an outcome of increasing importance. Most research in this area has been conducted within a certain Western countries’ context using measures that have not been validated within our region context.

scholarly journals Quality Of Life And End Stage Kidney Disease: Conceptual And Theoretical Issues

2020 ◽  
Vol 6 (3) ◽  
pp. 1-14
Author(s):  
Issa Al Salmi ◽  
Keyword(s):  
Quality Of Life ◽  
Kidney Disease ◽  
Theoretical Development ◽  
Health Related Quality ◽  
End Stage Kidney Disease ◽  
Related Quality ◽  
Health Related ◽  
End Stage ◽  
Theoretical Issues

Quality of Life (QoL) and Health-Related Quality of Life (HRQoL) are multidimensional concepts. Several tools have been developed to measure these concepts. The aim of this narrative review is to gain a general understanding of QoL concepts, track its theoretical development, and identify the theoretical framework underpinning the concept.

P0843EFFECT OF GROUP PSYCHO SOCIAL SUPPORT ON QUALITY OF LIFE AND MORTALITY WITH END STAGE KIDNEY DISEASE

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Zara Nisar ◽  
Hassan Sajjad ◽  
Nisar Anwar
Keyword(s):  
Quality Of Life ◽  
Group Therapy ◽  
Health Related Quality ◽  
End Stage Kidney Disease ◽  
Related Quality ◽  
Health Related ◽  
Group A ◽  
Group B ◽  
End Stage

Abstract Background and Aims The patients of end stage renal disease suffer a lot of psychological trauma as well as feel a lot of social burden. They mostly show psychological distress in different forms, be it impaired quality of life, depression or anxiety. The aim of our study was to find out the effect of supportive-expressive group therapy in end stage kidney disease patients in the outcome of better health related quality of life and survival. Method 181 patients were recruited in the study after consent between June 2012-June 2017. They were then assigned randomly to Group A supportive-expressive group therapy or to a Group B control group (no intervention). It was a double blinded randomized control trial. 115 patients were assigned to Group A and 66 were assigned to group B. The primary outcome was the effect on health related quality of life. Secondly, if it had any impact on survival. Significant predictors of survival were not analysed. Analysis was done by intention to treat. Results The patients of group A showed decrease in physical pain(p=0.002), mood elevation (p=0.04), compliance with treatment (p=0.001), reduced hopelessness (p=0.004), newly diagnosed depressive disorders (p=0.01) and better social life (p=0.003). Group A had 97% survival rate as compared to group B with 77%. Conclusion Supportive-expressive group therapy to patients with end stage kidney disease improves health related quality of life. It also has an effect on survival maybe because of compliance with treatment. We would like to further explore the role of Supportive-expressive group therapy in survival. Support groups should be provided to patients in developing countries like the setup of ours because it has a great impact on the betterment of the patient.

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