Paradoxical Arterial Wall Shrinkage May Contribute to Luminal Narrowing of Human Atherosclerotic Femoral Arteries

Circulation ◽  
1995 ◽  
Vol 91 (5) ◽  
pp. 1444-1449 ◽  
Author(s):  
Gerard Pasterkamp ◽  
Peter J. W. Wensing ◽  
Mark J. Post ◽  
Berend Hillen ◽  
Willem P. T. M. Mali ◽  
...  
1984 ◽  
Vol 246 (1) ◽  
pp. H97-H103 ◽  
Author(s):  
R. H. Cox ◽  
T. Tulenko ◽  
W. P. Santamore

Segments of carotid and femoral arteries were obtained from beagles subjected to cigarette smoking (12/day for 2 yr) and from unexposed controls. The segments were used for in vitro studies of active and passive mechanics, dose responses to norepinephrine (NE) and K+, connective tissue content, and water and electrolyte content and distribution. No significant differences in passive arterial wall mechanics or geometry at 100 mmHg were found, but a small (significant) increase in passive stiffness was found at wall loads corresponding to higher values of pressure for arteries from smokers. No significant changes in connective tissue composition were found at either site. No significant differences in maximum active force development were found at either site between the two groups. However, values of active force near the middle of the active force-length curve were lower (P less than 0.05) for smoker's arteries when expressed as a fraction of the maximum developed force. No differences in cell volume were found in arteries from the two groups. Mg2+ and K+ content of the femoral and Ca2+ content of both arteries were greater in the smokers. No difference in NE dose-response relations were found for either site. A statistically significant decrease in responsiveness to K+ was found for femoral arteries from smokers, but not for the carotids. The results of these studies demonstrate that some significant changes in arterial wall properties occur in beagle dogs exposed to chronic cigarette smoke.


2011 ◽  
Vol 52 (11) ◽  
pp. 1704-1712 ◽  
Author(s):  
R. Liga ◽  
C. Marini ◽  
M. Coceani ◽  
E. Filidei ◽  
M. Schlueter ◽  
...  

2019 ◽  
Vol 14 (6) ◽  
pp. 564-573 ◽  
Author(s):  
Juan F Arenillas ◽  
Nikki Dieleman ◽  
Daniel Bos

Purpose To review the current state of the art and future development of intracranial vessel wall imaging. Methods Recent literature review and expert opinion about intracranial arterial wall imaging. Results Intracranial large artery diseases represent an important cause of stroke and vascular cognitive impairment worldwide. Our traditional understanding of intracranial large artery diseases is based on the observation of luminal narrowing or occlusion with angiographic or ultrasound techniques. Recently, novel imaging techniques have made the intracranial artery wall accessible for noninvasive visualization. The main advantage of vessel-wall imaging as compared to conventional imaging techniques for visualization of intracranial arteries is the ability to detect vessel wall changes even before they get to cause any significant luminal stenosis. This diagnostic capacity is provoking a revolutionary change in the way we see the intracranial circulation. In this article, we will review the current state of magnetic resonance imaging and computed tomography-based intracranial arterial wall imaging, focusing on technical considerations and their clinical applicability. Moreover, we will provide the readers with our vision on the future development of vessel-wall imaging techniques. Conclusion Intracranial arterial wall imaging methods are gaining increasing potential to impact the diagnosis and treatment of patients with cerebrovascular diseases.


2006 ◽  
Vol 5 (1) ◽  
pp. 11-12
Author(s):  
Z KOBALAVA ◽  
V MOISEEV ◽  
Y KOTOVSKAYA ◽  
G KIYAKBAEV ◽  
E OZOVA

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