Reduced Coronary Flow Reserve in Hypercholesterolemic Patients Without Overt Coronary Stenosis

Circulation ◽  
1996 ◽  
Vol 94 (12) ◽  
pp. 3232-3238 ◽  
Author(s):  
Ikuo Yokoyama ◽  
Tohru Ohtake ◽  
Shin-ichi Momomura ◽  
Junichi Nishikawa ◽  
Yasuhito Sasaki ◽  
...  
Keyword(s):  
Coronary Flow Reserve ◽  
Coronary Stenosis ◽  
Coronary Flow ◽  
Flow Reserve

The Additive Diagnostic Role of Coronary Flow Reserve in Noninvasive Evaluation of Coronary Stenosis on Left Descending Artery Previously Detected by Multislice Computed Tomography

2012 ◽  
Vol 30 (3) ◽  
pp. 338-344 ◽  
Author(s):  
Zorica Mladenovic ◽  
Ana Djordjevic-Dikic ◽  
Dragan Tavciovski ◽  
Andjelka Ristic Angelkov ◽  
Zoran Jovic ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Flow Reserve ◽  
Coronary Stenosis ◽  
Coronary Flow ◽  
Multislice Computed Tomography ◽  
Noninvasive Evaluation ◽  
Flow Reserve ◽  
Diagnostic Role

scholarly journals RELATIONSHIP BETWEEN FRACTIONAL FLOW RESERVE (FFR) AND CORONARY FLOW RESERVE (CFR) BY PET IN IDENTIFYING CORONARY STENOSIS CAUSING MYOCARDIAL ISCHEMIA

2017 ◽  
Vol 69 (11) ◽  
pp. 133 ◽  
Author(s):  
Giulia Arena ◽  
Alberto Morello ◽  
Antonello D'Andrea ◽  
Bernardino Tuccillo ◽  
Francesco Punzo ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
Coronary Flow Reserve ◽  
Fractional Flow Reserve ◽  
Coronary Stenosis ◽  
Coronary Flow ◽  
Fractional Flow ◽  
Flow Reserve

scholarly journals Non-randomized comparison between revascularization and deferral for intermediate coronary stenosis with abnormal fractional flow reserve and preserved coronary flow reserve

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Doosup Shin ◽  
Joo Myung Lee ◽  
Seung Hun Lee ◽  
Doyeon Hwang ◽  
Ki Hong Choi ◽  
...  
Keyword(s):  
Coronary Flow Reserve ◽  
Fractional Flow Reserve ◽  
International Collaboration ◽  
Coronary Stenosis ◽  
Coronary Flow ◽  
Target Vessel ◽  
Fractional Flow ◽  
Patient Level ◽  
Flow Reserve ◽  
Significant Difference

AbstractLimited data are available regarding comparative prognosis after percutaneous coronary intervention (PCI) versus deferral of revascularization in patients with intermediate stenosis with abnormal fractional flow reserve (FFR) but preserved coronary flow reserve (CFR). From the International Collaboration of Comprehensive Physiologic Assessment Registry (NCT03690713), a total of 330 patients (338 vessels) who had coronary stenosis with FFR ≤ 0.80 but CFR > 2.0 were selected for the current analysis. Patient-level clinical outcome was assessed by major adverse cardiac events (MACE) at 5 years, a composite of all-cause death, target-vessel myocardial infarction (MI), or target-vessel revascularization. Among the study population, 231 patients (233 vessels) underwent PCI and 99 patients (105 vessels) were deferred. During 5 years of follow-up, cumulative incidence of MACE was 13.0% (31 patients) without significant difference between PCI and deferred groups (12.7% vs. 14.0%, adjusted HR 1.301, 95% CI 0.611–2.769, P = 0.495). Multiple sensitivity analyses by propensity score matching and inverse probability weighting also showed no significant difference in patient-level MACE and vessel-specific MI or revascularization. In this hypothesis-generating study, there was no significant difference in clinical outcomes between PCI and deferred groups among patients with intermediate stenosis with FFR ≤ 0.80 but CFR > 2.0. Further study is needed to confirm this finding.Clinical Trial Registration: International Collaboration of Comprehensive Physiologic Assessment Registry (NCT03690713; registration date: 10/01/2018).

scholarly journals Coronary Flow Reserve and Microcirculatory Resistance in Patients With Intermediate Coronary Stenosis

2016 ◽  
Vol 67 (10) ◽  
pp. 1158-1169 ◽  
Author(s):  
Joo Myung Lee ◽  
Ji-Hyun Jung ◽  
Doyeon Hwang ◽  
Jonghanne Park ◽  
Yongzhen Fan ◽  
...  
Keyword(s):  
Coronary Flow Reserve ◽  
Coronary Stenosis ◽  
Coronary Flow ◽  
Flow Reserve
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