scholarly journals High energy phosphate depletion and lactate accumulation in the interventricular septum and left ventricular free wall of the dog after total coronary occlusion.

1984 ◽  
Vol 54 (4) ◽  
pp. 405-413 ◽  
Author(s):  
R B Dunn
Keyword(s):  
Coronary Occlusion ◽  
Interventricular Septum ◽  
High Energy ◽  
Left Ventricular ◽  
Ventricular Free Wall ◽  
Free Wall ◽  
High Energy Phosphate ◽  
Left Ventricular Free Wall ◽  
Lactate Accumulation ◽  
Phosphate Depletion

scholarly journals Correlation between the periodontal treatment and ecocardiographic changes in adult dogs

Interação ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 43-57
Author(s):  
Daniel Paulino Júnior ◽  
Marina Queiroz Derruci ◽  
Leandro Zuccolotto Crivelenti ◽  
Brenda Faria Santos Gomes Parreira ◽  
Fernanda Gosuen Gonçalves Dias
Keyword(s):  
Left Ventricle ◽  
Periodontal Disease ◽  
Dental Treatment ◽  
Oral Treatment ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Periodontal Treatment ◽  
Ventricular Free Wall ◽  
Free Wall ◽  
Left Ventricular Free Wall

Periodontal disease is commonly diagnosed in dogs and has been associated with systemic lesions in several organs, however, studies correlating this oral condition with heart disease in the canine species are still scarce in the scientific literature. Thus, the objective of the present study was to evaluate such correlation in adult dogs, through serial echocardiographic exams and, nonetheless, to analyze the influence of dental treatment on cardiac function. For this, 60 dogs were used, distributed in two groups, the control (CG, n = 30: presence of periodontal disease, not submitted to oral treatment) and the treated (GT, n = 30: presence of periodontal disease and submitted to oral treatment). The animals of the CG were paired with those of the GT in terms of race, weight, age and degree of periodontal disease. Baseline echocardiographic examinations (D0) of the CG were performed and after 30 days (D30). In GT, examinations were also performed at D0 and D30, however, they were submitted to periodontal treatment after baseline measurements. The echocardiographic exams were performed at the Veterinary Cardiology Laboratory of the Veterinary Hospital of the University of Franca, to record and analyze the interventricular septum in diastole (SIVd), interventricular septum in systole (SIVs), diameter of the left ventricle in diastole (DVEd), left ventricular diameter in systole (EVDs), left ventricular free wall in diastole (PVEd) left ventricular free wall in systole (PVEs) shortening fraction of left ventricle (FS), final diastolic volume (VDF), final stroke volume (VSF), ejection fraction (EF), maximum pulmonary artery pressure gradient (max. GP AP) and left atrial and aortic artery diameter ratio (EA-AO). The results of the CG were statistically compared with those of the GT by means of simple analysis of variance (ANOVA). The data obtained regarding the SIVs, DVEd and PVEs parameters of the GT dogs at D30 showed a statistically significant decrease (p<0.05) when compared to the D30 of the CG. Thus, given the established methodology and the results found, it is possible to infer that periodontal treatment may benefit some cardiac parameters of adult dogs, improving their quality of life and survival.

Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats

1996 ◽  
Vol 271 (3) ◽  
pp. H1215-H1228 ◽  
Author(s):  
J. Kajstura ◽  
W. Cheng ◽  
R. Sarangarajan ◽  
P. Li ◽  
B. Li ◽  
...  
Keyword(s):  
Cell Death ◽  
Right Ventricle ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Ventricular Free Wall ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Free Wall ◽  
Fischer 344 Rats ◽  
Left Ventricular Free Wall ◽  
Fischer 344

To determine the effects of aging on myocyte cell death, Fischer 344 rats at 3, 7, 12, 16, and 24 mo of age were injected with myosin monoclonal antibody for the localization and quantification of necrotic myocyte cell death in the left ventricle, interventricular septum, and right ventricle. Conversely, the presence of DNA strand breaks in myocyte nuclei, indicative of programmed cell death, was evaluated by the terminal deoxynucleotidyl transferase assay and confirmed by DNA laddering. Myocyte necrosis, which involved nearly 1,000 myocytes in the left ventricular free wall at 3 mo, progressively increased with aging, reaching a value of 13,600 myocytes at 24 mo. Corre- sponding values in the interventricular septum were 300 and 9,400 myocytes. In the right ventricle, there were 270 necrotic myocytes at 3 mo and 9,000 at 24 mo. Programmed myocyte cell death was restricted to the left ventricular free wall and included 140 cells at 3 mo. This form of myocyte cell death increased at the subsequent age intervals, resulting in the involvement of 874 cells at 24 mo. The combination of necrosis and apoptosis in the left ventricular free wall was associated with 1,150 cells dying at 3 mo and 14,500 at 24 mo. In conclusion, myocyte cell death, apoptotic and necrotic in nature, constitutes an important determinant of the aging process, possibly mediating the occurrence of ventricular dysfunction and failure in the old heart.

scholarly journals Evaluation of echocardiographic variables of morphometry and function in horses submitted to minimally invasive partial pericardiotomy

2020 ◽  
Vol 72 (5) ◽  
pp. 1577-1585
Author(s):  
J.R. Silva ◽  
G.P. Meirelles ◽  
E.M. Busato ◽  
B.C. Brüler ◽  
R.G.D’O.C. Vilani ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Left Atrial ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Ventricular Free Wall ◽  
Internal Diameter ◽  
Free Wall ◽  
Left Ventricular Free Wall ◽  
Post Procedure ◽  
And Function

ABSTRACT This study aimed to evaluate the impact of minimally invasive partial pericardiotomy on echocardiographic variables of morphometry and function in healthy horses. Minimally invasive pericardiotomy was performed in six healthy horses. Echocardiographic evaluation was executed in different moments: prior to the surgical procedure (M0); 24 hours post procedure (M1); 72 hours post procedure (M2) and 28 days post procedure (M3). The following variables were measured: Right ventricular internal diameter in diastole and systole (RVd and RVs), interventricular septum thickness in diastole and systole (IVSd and IVSs), left ventricular internal diameter in diastole and systole (LVd and LVs), left ventricular free wall thickness in diastole and systole (LVFWd and LVFWs), aortic root diameter (Ao) and left atrial diameter (LA). From this data, the following variables were calculated: fractional shortening (FS%), fractional thickening of the interventricular septum (IVS%), fractional thickening of the left ventricular free wall (LVFW%) and the relationship between left atrial and aortic diameters (LA/Ao). After 28 days, a new thoracoscopy was performed for inspection of the thoracic cavity. In M1 and M2 ECO evaluations, a statistically significant change in LVFW and a decrease in RVd, LVd, LVFWs, LA, LVs, FS% and IVS was documented. Pericardiotomy is a promising technique in horses, with minor postoperative complication. The variations in the echocardiographic parameters were transient and did not cause hemodynamic damage to the animals.

Sequential rupture of the left ventricular free wall and of the interventricular septum after myocardial infarction. Surgical implications

1988 ◽  
Vol 21 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Bartolo Zingone ◽  
Erika Della Grazia ◽  
Aniello Pappalardo ◽  
Bernardo Benussi ◽  
Roberto Prandi ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Ventricular Free Wall ◽  
Free Wall ◽  
Left Ventricular Free Wall

Intracellular EDEMA does not adversely affect the ability to cryopreserve intact hearts

1993 ◽  
Vol 51 ◽  
pp. 278-279
Author(s):  
CL Hastings ◽  
RD Carlton ◽  
FG Lightfoot ◽  
AF Tryka
Keyword(s):  
Cell Injury ◽  
Median Sternotomy ◽  
Left Ventricular ◽  
Ventricular Free Wall ◽  
Hypoxic Cell ◽  
Free Wall ◽  
Sprague Dawley ◽  
Left Ventricular Free Wall ◽  
Sprague Dawley Rats

The earliest ultrastructural manifestation of hypoxic cell injury is the presence of intracellular edema. Does this intracellular edema affect the ability to cryopreserve intact myocardium? To answer this guestion, a model for anoxia induced intracellular edema (IE) was designed based on clinical intraoperative myocardial preservation protocol. The aortas of 250 gm male Sprague-Dawley rats were cannulated and a retrograde flush of Plegisol at 8°C was infused over 90 sec. The hearts were excised and placed in a 28°C bath of Lactated Ringers for 1 h. The left ventricular free wall was then sliced and the myocardium was slam frozen. Control rats (C) were anesthetized, the hearts approached by median sternotomy, and the left ventricular free wall frozen in situ immediately after slicing. The slam frozen samples were obtained utilizing the DDK PS1000, which was precooled to -185°C in liguid nitrogen. The tissue was in contact with the metal mirror for a dwell time of 20 sec, and stored in liguid nitrogen until freeze dry processing (Lightfoot, 1990).

scholarly journals Echocardiographic Findings in Friedreich's Ataxia

1976 ◽  
Vol 3 (4) ◽  
pp. 329-332 ◽  
Author(s):  
H.F. Gattiker ◽  
A. Davignon ◽  
A. Bozio ◽  
J. Batlle-Diaz ◽  
G. Geoffroy ◽  
...  
Keyword(s):  
Friedreich’S Ataxia ◽  
Left Ventricular ◽  
Friedreich's Ataxia ◽  
Ventricular Free Wall ◽  
Slight Reduction ◽  
Free Wall ◽  
Left Ventricular Free Wall ◽  
Echocardiographic Examination ◽  
Septal Hypertrophy ◽  
Echocardiographic Findings

SUMMARY:Echocardiographic examination of 21 patients with Friedreich's ataxia (age 7 to 28 years) showed cardiac abnormalities in 90% of the cases. They were characterized by varying degrees of septal hypertrophy in 81%, left ventricular free wall hypertrophy in 61%, and a slight reduction of left ventricular internal dimension in 57% of the cases. Asymmetric septal hypertrophy (ASH) with a septal/left ventricular free wall ratio of over 1.3 was found in 29% of the cases, and systolic anterior motion (SAM) of the mitral valve in three patients. Two other patients showed evidence of a different type of cardiomyopathy with marked symmetric left ventricular hypertrophy and marked left ventricular enlargement.

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