Functional Outcome in Rats Transferred to an Enriched Environment 15 Days After Focal Brain Ischemia

Stroke ◽  
1996 ◽  
Vol 27 (2) ◽  
pp. 324-326 ◽  
Author(s):  
Barbro B. Johansson
Keyword(s):  
Functional Outcome ◽  
Brain Ischemia ◽  
Enriched Environment ◽  
Focal Brain Ischemia

17β-estradiol and enriched environment accelerate cognitive recovery after focal brain ischemia

2009 ◽  
Vol 29 (6) ◽  
pp. 1215-1224 ◽  
Author(s):  
Ingegerd Söderström ◽  
Magnus Strand ◽  
Anna-Cajsa Ingridsson ◽  
Salmir Nasic ◽  
Tommy Olsson
Keyword(s):  
Brain Ischemia ◽  
Enriched Environment ◽  
Cognitive Recovery ◽  
17Β Estradiol ◽  
Focal Brain Ischemia

scholarly journals Sodium time course using23Na MRI in reversible focal brain ischemia in the monkey

2009 ◽  
Vol 30 (1) ◽  
pp. 219-223 ◽  
Author(s):  
George C. LaVerde ◽  
Charles A. Jungreis ◽  
Edwin Nemoto ◽  
Fernando E. Boada
Keyword(s):  
Brain Ischemia ◽  
Time Course ◽  
Focal Brain Ischemia

Multimodal assessment of neuroprotection applied to the use of MK-801 in the endothelin-1 model of transient focal brain ischemia

2007 ◽  
Vol 1153 ◽  
pp. 58-67 ◽  
Author(s):  
Slavianka Georgieva Moyanova ◽  
Lidia Vasileva Kortenska ◽  
Rumiana Gesheva Mitreva ◽  
Vyara Dincova Pashova ◽  
Richard Teke Ngomba ◽  
...  
Keyword(s):  
Brain Ischemia ◽  
Mk 801 ◽  
Endothelin 1 ◽  
Multimodal Assessment ◽  
Focal Brain Ischemia

Abstract W MP24: Modified Tibi (Thrombolysis in Brain Ischemia) Grading System for Assessment of Abnormal Residual Flow at Site of Intracranial Occlusion in Acute Ischemic Stroke

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Aftab Ahmad ◽  
Vijay K Sharma ◽  
Ghazala Basir ◽  
Khurshid Khan ◽  
Andrei V Alexandrov ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Functional Outcome ◽  
Brain Ischemia ◽  
High Probability ◽  
Arterial Occlusion ◽  
P Value ◽  
Grading System ◽  
Mean Flow ◽  
Diastolic Flow

Background and purpose: The intracranial blood flow at the site of arterial occlusion in acute ischemic stroke can be measured with Transracial Doppler (TCD) using the Thrombolysis in Brain Ischemia (TIBI) grading system. The TIBI ranges from 0 to 5, where 0 no flow and 5 normal flow. Our study’s aim is to modify the TIBI grading system in order to make it simple to implement in an acute stroke setting. METHODS: We classified Modified TIBI grading as: Grade 0- no flow, Grade 1- Bad flow: there is systolic flow but no diastolic flow or systolic flow with delayed acceleration and diastolic flow, Grade 2-Good flow: normal upstroke systolic flow and diastolic flow with decreased mean flow velocity compared to contralateral vessel by 30 %. We used the clotbust database to evaluate the modified TIBI scoring system. Poor long-term outcome was defined as modified rankin scale (MRS) score > 2. RESULTS: Total of 369 patients with acute ischemic stroke and intracranial arterial occlusion received IV r TPA. Median age was 71 years (IQ range: 58.7-79), Sex: women: 170(46.1%). Median NIHSS was 16 (IQ range: 12.7-2), 17/98 (17.3%) patients with modified TIBI 0, 73/205(35.6%) with modified TIBI 1 and 31/66( 47%) with modified TIBI 2 had achieved complete recanalization ( p value=0001). The multiple logistic regression model revealed Baseline higher NIHSS, systolic BP, glucose and modified TIBI grade 0 were independent negative predictor of complete recanalization. Patients with modified TIBI 3 had high probability of complete recanalization compared to TIBI 0(OR 3.14, CI 95%: 1.4-6.8, P=0.004).Poor outcome at 3 months (MRS>2) was found in 46/75(61.3%) patients with modified TIBI 0, 94/170(55.3%) with modified TIBI 1 and 19/38(33.3%) with modified TIBI 2(P value <0.004). On logistic model age, baseline NIHSS, glucose and TIBI 0 were independent negative predictors of good outcome.Although statistically insignificant but patients with modified TIBI 3 had a trend towards high probability of good functional outcome (OR: 1.73, CI 95%:0.73-4.12, p=0.20). CONCLUSION: Modified TIBI grading system is simplified version of TIBI grading and is easy to understand and apply clinically. It also predicts reliably the recanalization and functional outcome.

scholarly journals Correction to: Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats

2018 ◽  
Vol 224 (2) ◽  
pp. 739-740 ◽  
Author(s):  
Shotaro Otsuka ◽  
Harutoshi Sakakima ◽  
Takuto Terashi ◽  
Seiya Takada ◽  
Kazuki Nakanishi ◽  
...  
Keyword(s):  
Brain Damage ◽  
Brain Ischemia ◽  
Neuronal Apoptosis ◽  
Focal Brain Ischemia

IONOTROPIC GLUTAMATE RECEPTOR RESPONSES DURING EARLY STAGES OF FOCAL BRAIN ISCHEMIA

1993 ◽  
Vol 52 (3) ◽  
pp. 274
Author(s):  
C. A. Pardo ◽  
L. I. Martin ◽  
L. H. Monsein ◽  
C. D. Blackstone ◽  
R. N. Bryan
Keyword(s):  
Glutamate Receptor ◽  
Brain Ischemia ◽  
Ionotropic Glutamate Receptor ◽  
Early Stages ◽  
Focal Brain Ischemia

scholarly journals Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil

2011 ◽  
Vol 4 (1) ◽  
pp. 35 ◽  
Author(s):  
Junichi Yamane ◽  
Satoru Ishibashi ◽  
Masanori Sakaguchi ◽  
Toshihiko Kuroiwa ◽  
Yonehiro Kanemura ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Brain Ischemia ◽  
Functional Recovery ◽  
Mongolian Gerbil ◽  
Neural Stem Progenitor Cells ◽  
Focal Brain Ischemia
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