Abstract P030: Association of Ideal Cardiovascular Health and Plasminogen Activator Inhibitor-1 From Early Adulthood to Middle Age: the Coronary Artery Risk Development in Young Adults Study

Circulation ◽  
2019 ◽  
Vol 139 (Suppl_1) ◽  
Author(s):  
Lauren Y Lee ◽  
Douglas E Vaughan ◽  
Laura Colangelo ◽  
Donald M Lloyd-Jones ◽  
Sadiya S Khan
Keyword(s):  
Young Adults ◽  
Coronary Artery ◽  
Plasminogen Activator ◽  
Cardiovascular Health ◽  
Middle Age ◽  
Early Adulthood ◽  
Plasminogen Activator Inhibitor ◽  
Plasminogen Activator Inhibitor 1 ◽  
Ideal Cardiovascular Health ◽  
Activator Inhibitor

Increased plasminogen activator inhibitor-1 levels in patients with isolated coronary artery ectasia

2011 ◽  
Vol 33 (1) ◽  
pp. 120-123 ◽  
Author(s):  
Yuksel Cicek ◽  
Murtaza Emre Durakoglugil ◽  
Turan Erdogan ◽  
Adnan Yilmaz ◽  
Huseyin Avni Uydu ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Plasminogen Activator ◽  
Plasminogen Activator Inhibitor ◽  
Coronary Artery Ectasia ◽  
Plasminogen Activator Inhibitor 1 ◽  
Activator Inhibitor

Plasminogen Activator Inhibitor-1 Levels in Patients with Chronic Angina Pectoris with or without Angiographic Evidence of Coronary Sclerosis

1990 ◽  
Vol 63 (03) ◽  
pp. 336-339 ◽  
Author(s):  
K Huber ◽  
I Resch ◽  
Th Stefenelli ◽  
I Lang ◽  
P Probst ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Plasminogen Activator ◽  
Stable Coronary Artery Disease ◽  
Plasminogen Activator Inhibitor ◽  
Plasminogen Activator Inhibitor 1 ◽  
Artery Disease ◽  
Activator Inhibitor ◽  
Pai 1

SummaryIncreased plasma levels of plasminogen activator inhibitor-1 (PAI-1) have been shown to exist in 40 to 60% of patients with stable coronary artery disease and have been suggested to be responsible for the development of coronary thrombotic complications. However, it is also discussed whether PAI-1 elevation might mainly be due to variables like increased age or to reactive mechanisms caused e.g. by the chest pain itself. To exclude age dependent ui pain related influences, age-matched patients with stable angina pectoris (NHYA II) and angiographically proven coronary artery disease (CAD, n = 16) or without evidence for coronary sclerosis (variant angina, n = 10; angina-like syndrome with normal coronary angiogram, n = 5; non-CAD, n = 15) have been investigated for their plasma PAI-1 activity and t-PA antigen levels. The mean PAI activity in CAD patients (17.5 U/ml) was significantly higher than in non-CAD patients (9.6 U/ml) (p <0.0001). In the CAD patients no significant variation in plasma PAI-1 values could be demonstrated when related to the extent of the disease or to a history of previous myocardial infarction t-PA antigen was also elevated m CAD patients as compared to the non-CAD group (p <0.02). The results suggest therefore a strong correlation between coronary artery disease itself and elevated levels of components of the plasma fibrinolytic system.

Decreased Plasminogen Activator Inhibitor-1 Levels in Coronary Artery Aneurysmatic Patients

2004 ◽  
Vol 17 (3) ◽  
pp. 207-211 ◽  
Author(s):  
Ertugrul Ercan ◽  
Istemihan Tengiz ◽  
Can Duman ◽  
Cevad Sekuri ◽  
Emil Aliyev ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Plasminogen Activator ◽  
Plasminogen Activator Inhibitor ◽  
Plasminogen Activator Inhibitor 1 ◽  
Activator Inhibitor
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