scholarly journals Age, Sex, and Hypertension-Related Remodeling Influences Left Ventricular Torsion Assessed by Tagged Cardiac Magnetic Resonance in Asymptomatic Individuals

Circulation ◽  
2012 ◽  
Vol 126 (21) ◽  
pp. 2481-2490 ◽  
Author(s):  
Kihei Yoneyama ◽  
Ola Gjesdal ◽  
Eui-Young Choi ◽  
Colin O. Wu ◽  
W. Gregory Hundley ◽  
...  
Keyword(s):  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Left Ventricular ◽  
Left Ventricular Torsion ◽  
Ventricular Torsion ◽  
Asymptomatic Individuals

scholarly journals Left ventricular torsion rate and the relation to right ventricular function in pediatric pulmonary arterial hypertension

2018 ◽  
Vol 8 (3) ◽  
pp. 204589401879135 ◽  
Author(s):  
Melanie J. Dufva ◽  
Uyen Truong ◽  
Pawan Tiwari ◽  
Dunbar D. Ivy ◽  
Robin Shandas ◽  
...  
Keyword(s):  
Cardiac Magnetic Resonance ◽  
Pulmonary Arterial Hypertension ◽  
Magnetic Resonance ◽  
Arterial Hypertension ◽  
Right Ventricular ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Left Ventricular Torsion ◽  
Ventricular Torsion ◽  
Pulmonary Arterial

The right ventricle and left ventricle are physically coupled through the interventricular septum. Therefore, changes in the geometry and mechanics of one ventricle can directly affect the function of the other. In treatment of pediatric pulmonary arterial hypertension, the left ventricle is often overlooked, with clinical focus primarily on improving right ventricular function. Pediatric pulmonary arterial hypertension represents a disease distinct from adult pulmonary arterial hypertension based on etiology and survival rates. We aimed to assess left ventricular torsion rate in pediatric pulmonary arterial hypertension and its role in right ventricular dysfunction. Cardiac magnetic resonance images with tissue tagging were prospectively acquired for 18 pediatric pulmonary arterial hypertension (WHO class I) patients and 17 control subjects with no known cardiopulmonary disease. The pulmonary arterial hypertension cohort underwent cardiac magnetic resonance within 48 hours of clinically indicated right heart catheterization. Using right heart catheterization data, we computed single beat estimation of right ventricular end-systolic elastance (as a measure of right ventricular contractility) and ventricular vascular coupling ratio (end-systolic elastance/arterial afterload). Left ventricular torsion rate was quantified from harmonic phase analysis of tagged cardiac magnetic resonance images. Ventricular and pulmonary pressures and pulmonary vascular resistance were derived from right heart catheterization data. Right ventricular ejection fraction and interventricular septum curvature were derived from cardiac magnetic resonance. Left ventricular torsion rate was significantly reduced in pulmonary arterial hypertension patients compared to control subjects (1.40 ± 0.61° vs. 3.02 ± 1.47°, P < 0.001). A decrease in left ventricular torsion rate was significantly correlated with a decrease in right ventricular contractility (end-systolic elastance) ( r = 0.61, P = 0.007), and an increase in right ventricular systolic pressure in pulmonary arterial hypertension kids ( r = –0.54, P = 0.021). In both pulmonary arterial hypertension and control subjects, left ventricular torsion rate correlated with right ventricular ejection fraction (controls r = 0.45, P = 0.034) (pulmonary arterial hypertension r = 0.57, P = 0.032). In the pulmonary arterial hypertension group, interventricular septum curvature demonstrated a strong direct relationship with right ventricular systolic pressure ( r = 0.7, P = 0.001) and inversely with left ventricular torsion rate ( r = –0.57, P = 0.013). Left ventricular torsion rate showed a direct relationship with ventricular vascular coupling ratio ( r = 0.54, P = 0.021), and an inverse relationship with mean pulmonary arterial pressure ( r = –0.60, P = 0.008), and pulmonary vascular resistance ( r = –0.47, P = 0.049). We conclude that in pediatric pulmonary arterial hypertension, reduced right ventricular contractility is associated with decreased left ventricular torsion rate.

Abstract 2290: Assessment of Left Ventricular Torsion Using Two Dimensional Speckle Tracking Echocardiography: Comparison with Tagged Cardiac Magnetic Resonance.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Celine Goffinet ◽  
Fabien Chenot ◽  
Patrick Montant ◽  
David Vancraeynest ◽  
Anne-Catherine Pouleur ◽  
...  
Keyword(s):  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Intraclass Correlation ◽  
Left Ventricular ◽  
Left Ventricular Torsion ◽  
Ventricular Torsion ◽  
Highly Correlated ◽  
Key Parameter

Background. LV torsion from helically oriented myofibers is a key parameter of cardiac performance. Until now, LV torsion could only be assessed using tagged cardiac magnetic resonance (cMR). Because of its high spatial and temporal resolution, speckle tracking echocardiography (STE) could be an alternative to cMR. STE offers the opportunity to track myocardial motion independently of both cardiac translation and angle-dependency. The aim of this study was to evaluate the accuracy and reproducibility of STE for the estimation of LV torsion using cMR as the reference standard. Methods . Ten controls and 43 patients with a variety of cardiac disease underwent cMR and STE on the same day. STE datasets were analyzed using a prototype version of the 2DQ QLab software that allows to track speckles on a frame by frame basis in the endocardium and epicardium, and to derive LV torsion and twisting velocities. Care was taken to analyze cMR and STE data on similar short-axis slices, matched on basis of their end-diastolic internal dimensions. Inter- and intraobserver variabilities were estimated by two blinded observers for 20 patients. In 5 volunteers STE and cMR were repeated twice to assess test-retest reproducibility. Results . Measurements of endocardial, midwall and epicardial torsion by cMR and STE did not differ significantly from each other (12.6 ± 5.9° vs. 12.5 ± 5.6°, 10.7 ± 4.7° vs. 9.7 ± 4.1°, and 8.9 ± 4.1° vs. 8.5 ± 3.8°, all p=ns) and were highly correlated (r=0.96, 0.88 and 0.79), with only small intertechniques biases (0.11 ± 3.4°, 0.98 ± 4.7° and 0.4 ± 5.28°). Peak twisting velocities, obtained by deriving systolic torsion over time, were also similar between cMR and STE (54 ± 18°/s and 63 ± 23°/s, p=ns) and were highly correlated (r=0.74). The intra- and interobserver agreement for peak LV torsion measurements, assessed by the intraclass correlation coefficient, was equally good for cMR (ICC=0.98 and 0.96; bias 0.3 ± 2.9 and 0.65 ± 3.1°) and for STE (ICC=0.98 and 0.96; bias 0.05 ± 2.8 and 0.13 ± 4.7°). Test-retest reproducibility was also excellent. Conclusions . Our data show that, compared to cMR, STE allows LV torsion to be accurately and reproducibly measured. This should make LV torsion assessment more available in clinical and research cardiology.

The Improvement of Torsion Assessed by Cardiovascular Magnetic Resonance Feature Tracking after Coronary Artery Bypass Grafting: A Sensitive Index of Cardiac Function

2017 ◽  
Vol 20 (1) ◽  
pp. 026 ◽  
Author(s):  
Nan Cheng ◽  
Liuquan Cheng ◽  
Rong Wang ◽  
Lin Zhang ◽  
Changqing Gao
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Ejection Fraction ◽  
Cardiac Function ◽  
Feature Tracking ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Rapid Acquisition ◽  
Left Ventricular Torsion ◽  
Ventricular Torsion

Objective: The aim of this study was to quantify left ventricular torsion by newly applied cardiovascular magnetic resonance feature tracking (CMR-FT), and to evaluate the clinical value of the ventricular torsion as a sensitive indicator of cardiac function by comparison of preoperative and postoperative torsion.Methods: A total of 54 volunteers and 36 patients with previous myocardial infarction (MI) and LV ejection fraction (EF) between 30%-50% were screened preoperatively or postoperatively by MRI. The patients’ short axis views of the whole heart were acquired, and all patients had a scar area >75% in at least one of the anterior or inferior segments. Their apical and basal rotation values were analyzed by feature tracking, and the correlation analysis was performed for the improvement of LV torsion and ejection fraction after CABG. The intra- and inter-observer reliabilities of torsion measured by CMR-FT were assessed.Results: In normal hearts, the apex rotated counterclockwise in the systolic period with the peak rotation as 10.2 ± 4.8°, and the base rotated clockwise as the peak value was 7.0 ± 3.3°. There was a timing hiatus between the apex and base untwisting, during which period the heart recoils and its suction sets the stage for the following rapid filling period. The postoperative torsion and rotation significantly improved compared with preoperative ones. However, the traditional indicator of cardiac function, ejection fraction, didn’t show significant improvement.Conclusion: Left ventricular torsion derived from CMR-FT, which does not require specialized CMR sequences, was sensitive to patients with low ejection fraction whose cardiac function significantly improved after CABG. The rapid acquisition of this measurement has potential for the assessment of cardiac function in clinical practice. 

Association of cardiovascular risk factors on myocardial perfusion and fibrosis in asymptomatic individuals: cardiac magnetic resonance study

2018 ◽  
Vol 59 (11) ◽  
pp. 1300-1308 ◽  
Author(s):  
Min Jae Cha ◽  
Sung Mok Kim ◽  
Hyun Su Kim ◽  
Yiseul Kim ◽  
Yeon Hyeon Choe
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Myocardial Perfusion ◽  
Cardiovascular Risk Factors ◽  
Volume Fraction ◽  
Left Ventricular ◽  
Coronary Microvascular Dysfunction ◽  
Asymptomatic Individuals

Background Myocardial perfusion reserve index (MPRI) and extracellular volume fraction (ECV) on cardiac magnetic resonance (CMR) are known to quantify coronary microvascular dysfunction and myocardial fibrosis, respectively. Purpose To demonstrate that cardiovascular risk factors such as hypertension, diabetes, hyperlipidemia, and smoking are correlated with MPRI and ECV on CMR in asymptomatic individuals. Material and Methods Between October 2013 and July 2014, 196 individuals underwent CMR. After excluding those with chest pain, arrhythmia, and obstructive coronary artery disease, participants were divided into five groups: those without risk factor (n = 26) and those with one (n = 43), two (n = 35), three (n = 24), or four (n = 6) risk factors. MPRI and ECV were obtained on perfusion CMR and pre- and post-T1 mapping, respectively. Results A total of 134 asymptomatic individuals (109 men, 25 women; mean age = 54.4 ± 7.08 years; body mass index [BMI] = 24.96 ± 2.76 kg/m2; Framingham risk score [FRS] = 7.71 ± 5.21) were included. The Jonckheere-Terpstra test demonstrated trends of increasing BMI, FRS, and left ventricular mass index (all P values < 0.001), but decreasing MPRI ( P = 0.001) with increasing numbers of risk factors. Stepwise multiple linear regression demonstrated that an increasing number of cardiovascular risk factors was an independent predictor of MPRI ( P = 0.001). However, there was no significant association between the number of risk factors and ECV ( P = 0.99). Conclusion We demonstrated that an increasing number of cardiovascular risk factors is significantly associated with reduced MPRI, but not with ECV on CMR.

scholarly journals Quantification of Left Ventricular Torsion and Diastolic Recoil Using Cardiovascular Magnetic Resonance Myocardial Feature Tracking

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e109164 ◽  
Author(s):  
Johannes T. Kowallick ◽  
Pablo Lamata ◽  
Shazia T. Hussain ◽  
Shelby Kutty ◽  
Michael Steinmetz ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Feature Tracking ◽  
Left Ventricular ◽  
Left Ventricular Torsion ◽  
Ventricular Torsion
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