Abstract 100: Electrocardiographic Changes in Patients ≥ 100 Years Of Age

Hypertension ◽  
2012 ◽  
Vol 60 (suppl_1) ◽  
Author(s):  
Saurabh Thakar ◽  
Vijay Shetty ◽  
Adnan Sadiq ◽  
Edgar Lichstein ◽  
Gerald Hollander ◽  
...  

Background: Centenarian population in the United States is increasing, and cardiovascular disease is the most common cause of death in this group of patients. We report electrocardiographic changes in a group of 124 centenarians. METHODS: We included ECGs of 124 patients aged 100 to 112 years (mean age 102 years), who were seen either on office visits or on recent admission to the hospital. ECGs were analyzed by 2 different investigators. Results: Women were at least 2 times men in number (31% vs 69%, 39 vs 85 of 124); thus women outlived men in the centenarian group. 58% (72 of 124) patients had normal sinus rhythm and only 7 of 124 patients (6%, all women) had normal ECGs. The most common electrocardiographic abnormalities were: left-axis deviation (29%, 36 of 124), atrial fibrillation (AF) (27%, 34 of 124), right bundle branch block (15%, 18 of 124), left anterior fascicular block (14%, 17 of 124), left ventricular hypertrophy (14%, 17 of 124), first-degree atrioventricular (AV) block (13%, 16 of 124), nonspecific ST-T changes (13%, 16 of 124), premature atrial complexes (13%, 16 of 124), premature ventricular complexes (10%, 13 of 124) and pacemaker rhythm (10%, 13 of 124). Almost all Q waves were suggestive of old inferior wall infarcts and were present in 8% (10 of 124) of patients. Only 3 centenarians had QTc prolongation. Conclusion: Fewer men live long enough to reach 100 years of age, consistent with higher incidence of ischemic heart disease in men. Centenarians had higher incidence of AF indicative of increased incidence of AF with age. Increased incidence of left-axis deviation, left anterior fascicular block and left ventricular hypertrophy in centenarians can be attributed to age related cardiac hypertrophy and prevalence of hypertension. Also higher prevalence of conduction disturbances including AV block and bundle branch block indicates that a degenerative conduction system disorder may progress with advancing age. The finding of pacemaker rhythm in a few subjects confirms that pacemaker implantation may allow some patients to reach extreme longevity. Overall centenarians represent a model of successful aging and have satisfactory electrocardiographic framework that reflects a good cardiac function, contributing to attainment of extreme longevity.

2003 ◽  
Vol 13 (3) ◽  
pp. 258-263 ◽  
Author(s):  
Junko Shiono ◽  
Hitoshi Horigome ◽  
Seiyo Yasui ◽  
Tomoyuki Miyamoto ◽  
Miho Takahashi-Igari ◽  
...  

Background:Cardiac rhabdomyomas associated with tuberous sclerosis induce various abnormalities in the electrocardiogram. Electrocardiographic evidence of ventricular hypertrophy may appear if the tumour is electrically active. To our knowledge, electrocardiographic evidence of ventricular hypertrophy has been reported only in association with congestive heart failure. Follow-up studies of changes in electrocardiographic findings are also lacking.Methods:We studied 21 consecutive patients with cardiac rhabdomyoma associated with tuberous sclerosis, 10 males and 11 females, aged from the date of birth to 9 years at diagnosis. The mean period of follow-up was 53 months. None of the patients developed congestive heart failure. We evaluated the electrocardiographic changes during the follow-up, and their association with echocardiographic findings.Results:Of the 21 patients, 12 showed one or more abnormalities on the electrocardiogram at presentation, with five demonstrating right or left ventricular hypertrophy. In all of these five cases, the tumours were mainly located in the respective ventricular cavity. In one patient with a giant tumour expanding exteriorly, there was marked left ventricular hypertrophy on the electrocardiogram. Followup studies showed spontaneous regression of the tumours in 12 of 19 patients, with abnormalities still present in only 7 patients. A gradual disappearance of left ventricular hypertrophy as seen on the electrocardiogram was noted in the patient with marked left ventricular hypertrophy at presentation in parallel with regression of the tumour.Conclusions:The presence of cardiac rhabdomyomas in patients with tuberous sclerosis might explain the ventricular hypertrophy seen on the electrocardiogram through its electrically active tissue without ventricular pressure overload or ventricular enlargement, although pre-excitation might affect the amplitude of the QRS complex. Even in cases with large tumours, nonetheless, the electric potential might not alter the surface electrocardiogram if the direction of growth of the tumour is towards the ventricular cavity. In many cases, electrocardiographic abnormalities tend to disappear, concomitant with regression of the tumours.


1990 ◽  
Vol 28 (2) ◽  
pp. 215-221 ◽  
Author(s):  
Pietro Vincenzo Fragola ◽  
Camillo Autore ◽  
Giancarlo Ruscitti ◽  
Antonella Picelli ◽  
Dario Cannata

2015 ◽  
Vol 4 (4) ◽  
pp. 151-58
Author(s):  
Hooman Angoorani ◽  
Mohamadsadegh Haghi

Background: Sudden cardiac death (SCD) is the leading cause of death in athletes during sport. Electrocardiography (ECG) is a useful tool to detect underlying cardiovascular conditions that may increase the risk for SCD. The aim of the present study is to evaluate common ECG changes among professional football players. Materials and Methods: All football players of Iranian Premier League in season 2013-2014 participated in this descriptive study (258 football players). The standard 12-lead ECGs were evaluated and ECG analysis was performed according to previously described criteria. Results: Electrocardiogram evaluation showed that the percent of ECG changes was as follows; Inverted T (7.7%), Depression ST (2.3%), Bradycardia (0.3%), St Elevation (2.7%), Left ventricular hypertrophy (1.5%), Left bundle branch block (0.3%), Incomplete right bundle branch (0.3%), Incomplete left anterior bundle (0.8%), branch Incomplete left posterior bundle branch (1.1%), Wolf Parkinson white (0.3%), Left axis deviation (1.5), Right axis deviation (2.3%), ECG finding in favor of HCM (3.1%) and finally ECG finding in favor of IHD(10%). Conclusion: Most electrocardiographic variables in Iranian professional football players were lower than the worldwide football players that may be related to the lower level of physical fitness among Iranian football players.[GMJ.2015;4(4):151-58]


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