Response to Estimation of Aortic Blood Pressures and Pulse Wave Velocity in Obese Children: A Technological Perspective

In a study undertaken to evaluate the clinical effectiveness of two behavioral treatments for essential hypertension (biofeedback on arterial pulse-wave velocity and progressive relaxation) 24 hypertensive subjects were randomly assigned to either a relaxation or biofeedback treatment group for 5 weekly sessions. In a second stage of the study 16 of the original subjects received both biofeedback and relaxation treatments during 5 additional weekly sessions. Results indicated that biofeedback and relaxation were equally effective in initial lowering of blood pressure in hypertensives. Although biofeedback training led to superior reductions at the 3-mo. follow-up point, after 1 yr. the blood pressures of both groups were not only equal but well below those presented at the beginning of the study.

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Obese children show increased intimal wall thickness and decreased pulse wave velocity

Clinical Physiology and Functional Imaging ◽

10.1111/j.1475-097x.2008.00806.x ◽

2008 ◽

Vol 28 (5) ◽

pp. 287-293 ◽

Cited By ~ 65

Author(s):

Frida Dangardt ◽

Walter Osika ◽

Reinhard Volkmann ◽

Li-Ming Gan ◽

Peter Friberg

Keyword(s):

Pulse Wave Velocity ◽

Wave Velocity ◽

Wall Thickness ◽

Pulse Wave ◽

Obese Children

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Volume status and arterial blood pressures are associated with arterial stiffness in hemodialysis patients

The International Journal of Artificial Organs ◽

10.1177/0391398818778212 ◽

2018 ◽

Vol 41 (7) ◽

pp. 378-384 ◽

Cited By ~ 2

Author(s):

Alper Erdan ◽

Abdullah Ozkok ◽

Nadir Alpay ◽

Vakur Akkaya ◽

Alaattin Yildiz

Keyword(s):

Blood Pressure ◽

Arterial Stiffness ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Pressure ◽

Pulse Wave ◽

Augmentation Index ◽

Mean Blood Pressure ◽

Aortic Blood ◽

Aortic Blood Pressure

Background: Arterial stiffness is a strong predictor of mortality in hemodialysis patients. In this study, we aimed to investigate possible relations of arterial stiffness with volume status determined by bioimpedance analysis and aortic blood pressure parameters. Also, effects of a single hemodialysis session on these parameters were studied. Methods: A total of 75 hemodialysis patients (M/F: 43/32; mean age: 53 ± 17) were enrolled. Carotid-femoral pulse wave velocity, augmentation index, and aortic pulse pressure were measured by applanation tonometry before and after hemodialysis. Extracellular fluid and total body fluid volumes were determined by bioimpedance analysis. Results: Carotid-femoral pulse wave velocity (9.30 ± 3.30 vs 7.59 ± 2.66 m/s, p < 0.001), augmentation index (24.52 ± 9.42 vs 20.28 ± 10.19, p < 0.001), and aortic pulse pressure (38 ± 14 vs 29 ± 8 mmHg, p < 0.001) significantly decreased after hemodialysis. Pre-dialysis carotid-femoral pulse wave velocity was associated with age (r2 = 0.15, p = 0.01), total cholesterol (r2 = 0.06, p = 0.02), peripheral mean blood pressure (r2 = 0.10, p = 0.005), aortic-mean blood pressure (r2 = 0.06, p = 0.02), aortic pulse pressure (r2 = 0.14, p = 0.001), and extracellular fluid/total body fluid (r2 = 0.30, p < 0.0001). Pre-dialysis augmentation index was associated with total cholesterol (r2 = 0.06, p = 0,02), aortic-mean blood pressure (r2 = 0.16, p < 0.001), and aortic pulse pressure (r2 = 0.22, p < 0.001). Δcarotid-femoral pulse wave velocity was associated with Δaortic-mean blood pressure (r2 = 0.06, p = 0.02) and inversely correlated with baseline carotid-femoral pulse wave velocity (r2 = 0.29, p < 0.001). Pre-dialysis Δaugmentation index was significantly associated with Δaortic-mean blood pressure (r2 = 0.09, p = 0.009) and Δaortic pulse pressure (r2 = 0.06, p = 0.03) and inversely associated with baseline augmentation index (r2 = 0.14, p = 0.001). In multiple linear regression analysis (adjusted R2 = 0.46, p < 0.001) to determine the factors predicting Log carotid-femoral pulse wave velocity, extracellular fluid/total body fluid and peripheral mean blood pressure significantly predicted Log carotid-femoral pulse wave velocity (p = 0.001 and p = 0.006, respectively). Conclusion: Carotid-femoral pulse wave velocity, augmentation index, and aortic pulse pressure significantly decreased after hemodialysis. Arterial stiffness was associated with both peripheral and aortic blood pressure. Furthermore, reduction in arterial stiffness parameters was related to reduction in aortic blood pressure. Pre-dialysis carotid-femoral pulse wave velocity was associated with volume status determined by bioimpedance analysis. Volume control may improve not only the aortic blood pressure measurements but also arterial stiffness in hemodialysis patients.

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INCREASED VASCULAR DIAMETER AND DECREASED PULSE WAVE VELOCITY IN OBESE CHILDREN

Atherosclerosis Supplements ◽

10.1016/s1567-5688(08)70599-3 ◽

2008 ◽

Vol 9 (1) ◽

pp. 148-149

Author(s):

F. Dangardt ◽

W. Osika ◽

L. Gan ◽

R. Volkmann ◽

S. Mårild ◽

...

Keyword(s):

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Wave ◽

Obese Children

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Aortic stiffness in obese children and adolescents: Comparison of two distance measures of carotid–femoral pulse wave velocity

Artery Research ◽

10.1016/j.artres.2013.09.004 ◽

2013 ◽

Vol 7 (3-4) ◽

pp. 186 ◽

Cited By ~ 5

Author(s):

Kristian Nebelin Hvidt ◽

Michael Hecht Olsen ◽

Jens-Christian Holm ◽

Hans Ibsen

Keyword(s):

Pulse Wave Velocity ◽

Children And Adolescents ◽

Wave Velocity ◽

Aortic Stiffness ◽

Pulse Wave ◽

Distance Measures ◽

Obese Children

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Ambulatory aortic blood pressure, wave reflections and pulse wave velocity are elevated during the third in comparison to the second interdialytic day of the long interval in chronic haemodialysis patients

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfv090 ◽

2015 ◽

Vol 30 (12) ◽

pp. 2046-2053 ◽

Cited By ~ 25

Author(s):

Georgios Koutroumbas ◽

Panagiotis I. Georgianos ◽

Pantelis A. Sarafidis ◽

Athanase Protogerou ◽

Antonios Karpetas ◽

...

Keyword(s):

Blood Pressure ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pressure Wave ◽

Pulse Wave ◽

Chronic Haemodialysis ◽

Wave Reflections ◽

The Third ◽

Aortic Blood ◽

Aortic Blood Pressure

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MON-LB52 Evaluation of Arterial Stiffness in Acromegaly Patients

Journal of the Endocrine Society ◽

10.1210/jendso/bvaa046.2110 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

Author(s):

sevil alagüney ◽

Goknur Yorulmaz ◽

Toygar Ahmet Kalkan ◽

Kadir Ugur Mert ◽

Muhammet Dural ◽

...

Keyword(s):

Blood Pressure ◽

Arterial Stiffness ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Wave ◽

Augmentation Index ◽

Morbidity And Mortality ◽

Increased Risk ◽

Study Results ◽

Blood Pressures

Abstract Acromegaly is associated with increased morbidity and mortality primarily attributed to cardiovascular and cerebrovascular diseases, thus demonstrating the negative arterial impact of chronic GH and IGF-1 excess. There are limited and conflicting data regarding coronary artery disease (CAD) in acromegaly that consists mainly of heterogeneous cohorts and pathological reviews of old case series. Increased arterial stiffness is associated with an increased risk of cardiovascular events such as myocardial infarction. Arterial stiffness may measured from pulse wave velocity(PWV). In this study we aimed to evaluate the association between pulse wave velocity and aortic augmentation index in acromegalic patients. Methods: Our study population consists of a consecutive subset of 32 acromegalic patients and 19 control. Acromegalic patients IGF 1 levels were noted. All patients BMI, age, blood pressure, gender also were noted. Also pulse pressure, central blood pressures were measured by non-invasive central blood pressure measurement device (SphygmoCor). Pulse wave velocity and aortic augmentation index were measured by the same device. Results: A total of 32 acromegalic patients and 19 control were enrolled in the study. Body mass index and gender were not significantly different between the groups. Aortic augmentation index (5 vs. 6, p =0,685) variables weren’t significantly different in the study. Systolic and diastolic blood pressures were significantly high in the acromegalic group. (130/82 vs. 120/70) PWV was significantly high in the acromegalic group. (13 vs 11,5 p=0,002)Conclusions: Our study results suggest that acromegaly patients have worse arterial stiffness due to increased pulse wave velocity. Acromegaly is associated with increased morbidity and mortality primarily attributed to cardiovascular problems. We thought that it may be a guiding method in disease management since it can be an early marker of cardiovascular risk.Keywords: acromegaly, pulse wave velocity, aortic augmentation index

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Relation between blood pressure and pulse wave velocity for human arteries

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1814392115 ◽

2018 ◽

Vol 115 (44) ◽

pp. 11144-11149 ◽

Cited By ~ 46

Author(s):

Yinji Ma ◽

Jungil Choi ◽

Aurélie Hourlier-Fargette ◽

Yeguang Xue ◽

Ha Uk Chung ◽

...

Keyword(s):

Blood Pressure ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

High Pressures ◽

Pulse Wave ◽

Blood Pressure Monitoring ◽

Pressure Monitoring ◽

Noninvasive Blood Pressure ◽

Blood Pressures ◽

Human Arteries

Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly, and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens−Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.

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