Regulatory Role Of Thrombin In Allergic Bronchial Asthma

Author(s):  
Takehiro Takagi ◽  
Yasushi Miyake ◽  
Kentaro Fujiwara ◽  
Masahiro Onishi ◽  
Masahiro Naito ◽  
...  
Lung ◽  
2011 ◽  
Vol 190 (2) ◽  
pp. 189-198 ◽  
Author(s):  
Atsushi Fujiwara ◽  
Osamu Taguchi ◽  
Takehiro Takagi ◽  
Corina N. D’Alessandro-Gabazza ◽  
Daniel Boveda-Ruiz ◽  
...  

2005 ◽  
Vol 28 (3) ◽  
pp. 257-270 ◽  
Author(s):  
Aysefa Doganci ◽  
Kerstin Sauer ◽  
Roman Karwot ◽  
Susetta Finotto

2019 ◽  
Vol 10 ◽  
Author(s):  
Yoshinori Takahashi ◽  
Tetsu Kobayashi ◽  
Corina N. D'Alessandro-Gabazza ◽  
Masaaki Toda ◽  
Kentaro Fujiwara ◽  
...  

Author(s):  
Ivan I. Balabolkin ◽  
I. E. Smirnov

In the review, based on the data of the modern literature and authors’ own research, features of the development of allergic bronchial asthma (BA) in children are presented. There is also considered the important role of atopy, IgE-mediated mechanism, activation of Th2-lymphocytes, mast cells, basophils, eosinophils, increased production of mediators, chemokines and cytokines (IL4, IL5, IL8, IL13, IL17, IL22, IL25, IL33, GM-CSF, TNFα) in its pathogenesis and Th2 endotypes and phenotypes of allergic asthma. Modern therapeutic approaches to the treatment of allergic asthma based on the use of inhaled glucocorticosteroids, leukotriene receptor antagonists, short and long-acting β2-agonists, long-acting theophylline, omalizumab, and allergen-specific immunotherapy have been determined.


2000 ◽  
Vol 30 (2) ◽  
pp. 178-186 ◽  
Author(s):  
Braun ◽  
Lommatzsch ◽  
Renz

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