Neural Conduits Containing Lentiviral Vectors Overexpressing Low Molecular Weight FGF-2 Facilitate Motor Axon Regeneration and Functional Recovery After Rat Femoral Nerve Injury

2019 ◽  
Vol 9 (3) ◽  
pp. 408-411
Author(s):  
Guoqiang Yu ◽  
Aili Xu ◽  
Zhenyu Zhao ◽  
Xinguang Yu
2016 ◽  
Vol 116 (3) ◽  
pp. 1408-1417 ◽  
Author(s):  
Jill Cannoy ◽  
Sam Crowley ◽  
Allen Jarratt ◽  
Kelly LeFevere Werts ◽  
Krista Osborne ◽  
...  

Following peripheral nerve injury, moderate daily exercise conducted on a level treadmill results in enhanced axon regeneration and modest improvements in functional recovery. If the exercise is conducted on an upwardly inclined treadmill, even more motor axons regenerate successfully and reinnervate muscle targets. Whether this increased motor axon regeneration also results in greater improvement in functional recovery from sciatic nerve injury was studied. Axon regeneration and muscle reinnervation were studied in Lewis rats over an 11 wk postinjury period using stimulus evoked electromyographic (EMG) responses in the soleus muscle of awake animals. Motor axon regeneration and muscle reinnervation were enhanced in slope-trained rats. Direct muscle (M) responses reappeared faster in slope-trained animals than in other groups and ultimately were larger than untreated animals. The amplitude of monosynaptic H reflexes recorded from slope-trained rats remained significantly smaller than all other groups of animals for the duration of the study. The restoration of the amplitude and pattern of locomotor EMG activity in soleus and tibialis anterior and of hindblimb kinematics was studied during treadmill walking on different slopes. Slope-trained rats did not recover the ability to modulate the intensity of locomotor EMG activity with slope. Patterned EMG activity in flexor and extensor muscles was not noted in slope-trained rats. Neither hindblimb length nor limb orientation during level, upslope, or downslope walking was restored in slope-trained rats. Slope training enhanced motor axon regeneration but did not improve functional recovery following sciatic nerve transection and repair.


2019 ◽  
Vol 25 (3) ◽  
pp. 181-183
Author(s):  
Buket Tuğan Yıldız ◽  
Mustafa Gökçe ◽  
Deniz Tuncel ◽  
Hamza Şahin ◽  
Muhammet Yusuf Uslusoy

2008 ◽  
Vol 15 (1) ◽  
pp. 105-107 ◽  
Author(s):  
Andrea Porzionato ◽  
Veronica Macchi ◽  
Fabio Fenato ◽  
Anna Parenti ◽  
Raffaele De Caro

2018 ◽  
Vol 43 (3) ◽  
pp. 573-577 ◽  
Author(s):  
Jinxin Yang ◽  
Zhendong Zhang ◽  
Hui Cheng ◽  
Kai Xiao ◽  
Dianzhong Luo ◽  
...  

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Manzhou Lin ◽  
Guojie Long ◽  
Ming Chen ◽  
Weice Chen ◽  
Jian Mo ◽  
...  

1970 ◽  
Vol 28 (2) ◽  
pp. 121-124
Author(s):  
Selina Daisy ◽  
Quazi Deen Mohammad ◽  
Azharul Hoque ◽  
Badrul Alam ◽  
Badrul Haque ◽  
...  

After introduction of EMG at Dhaka Medical Collage onJanuary 01, 2006, a total of 415 cases referred to EMGlaboratory for electrophysiological evaluation over a periodof two years(January 01, 2006 to December 31, 2007). Among these, 7cases diagnosed as iatrogenic nerve injuries. The subtypesof iatrogenic nerve injuries were:1. Accessory nerve injury: three, 2. Femoral nerve injury:one, 3. Sciatic nerve injury: one,4. Lumbar sacral plexus injury: one, 5. Combined sciaticand femoral nerve injury: oneIn order to investigate the causes, diagnosis & preventionof iatrogenic nerve injuries; we have reviewed 7 cases ofiatrogenic nerve injuries. The peripheral nerve injuriesoccurred due to lack of proper awareness of medicalpersonals. These injuries are iatrogenic injuries so it isuseful to review the mode of injuries and means ofprevention.DOI: 10.3329/jbcps.v28i2.5373J Bangladesh Coll Phys Surg 2010; 28: 121-124


Sign in / Sign up

Export Citation Format

Share Document