Salivary Cortisol Awakening Response as a Predictor for Depression Severity in Adult Patients with a Major Depressive Episode Performing a Daily Exercise Program

<b><i>Introduction:</i></b> The hypothalamic-pituitary-adrenal axis function in depression has been the subject of considerable interest, and its function has been tested with a variety of methods. We investigated associations between saliva cortisol at awakening and the 24-h urine cortisol output, both measured at study baseline, with endpoint depression scores. <b><i>Methods:</i></b> Patients were admitted to a psychiatric inpatient ward with a major depressive episode and were started on fixed duloxetine treatment. They delivered saliva samples at awakening and 15, 30, and 60 min post-awakening and sampled urine for 24 h. Subsequently, they started a daily exercise program maintained for a 9-week period. Clinician-rated depression severity was blindly assessed with the Hamilton Depression Rating 6-item subscale (HAM-D₆). The cortisol awakening response was quantified by the area under the curve with respect to the ground (AUC_G) and with respect to the rise (AUC_I) using saliva cortisol levels in the 1-h period after awakening. Analysis of expected associations between depression severity, AUC_G, AUC_I, exercise, and 24-h cortisol output was performed in a general linear model. <b><i>Results:</i></b> In all, 35 participants delivered saliva or 24-h urine samples. The mean age was 49.0 years (SD = 11.0) with 48.6% females with a mean baseline HAM-D₆ score of 12.2 (SD = 2.3). In a statistical model investigating the association between HAM-D₆ at week 9 as a dependent variable and AUC_I, concurrent HAM-D₆, gender, smoking, and exercise volume as covariates, we found a significant effect of AUC_I, concurrent HAM-D₆, and exercise. The following statistics were found: AUC_I (regression coefficient 0.008; <i>F</i> value = 9.1; <i>p</i> = 0.007), concurrent HAM-D₆ (regression coefficient 0.70; <i>F</i> value = 8.0; <i>p</i> = 0.01), and exercise (regression coefficient −0.005; <i>F</i> value = 5.7; <i>p</i> = 0.03). The model had an <i>R</i>² of 0.43. The association between HAM-D₆ endpoint scores and the AUC_I showed that higher AUC_I values predicted higher HAM-D₆ endpoint values. The association between HAM-D₆ endpoint scores and the exercise level showed that a high exercise level was associated with lower HAM-D₆ endpoint values. <b><i>Conclusion:</i></b> The results thus showed that high AUC_I values predicted less improvement of depression and high exercise levels predicted more improvement of depression. These findings need to be confirmed in larger samples to test if more covariates can improve prediction of depression severity.

Access to exercise for people with visual impairments during the Coronavirus-19 pandemic

People with blindness and visual impairments have reduced access to exercise compared to the general population during typical societal functioning. The Coronavirus-19 pandemic completely disrupted daily life for most individuals worldwide, and in the United Kingdom, a stay-at-home order was enforced. One of the sole reasons an individual could leave their home was for the purpose of daily exercise. Here, we examined how the UK national lockdown impacted access to exercise for people with blindness and visual impairment. We used a mixed methods design, collecting quantitative data from two established measures (the Exercise Barriers and Benefits Scale and the International Physical Activity Questionnaire), and qualitative data from open-ended questions. We found that, during the initial stages of the lockdown, perceived barriers to exercise increased compared to pre-pandemic levels, driven by factors, such as the closure of exercise facilities and additional difficulties posed by social distancing. Interestingly, during the later stages of the UK Coronavirus-19 response, perceived barriers decreased to lower than pre-pandemic levels. Thematic analysis indicated that this may have been due to participants finding new online methods to exercise at home, in combination with the tentative reopening of facilities.

Technology Use Among Older Adults to Manage their Health During a Global Pandemic

Risk of severe COVID-19 illness increases with age, and older adults are more likely to be hospitalized and die from COVID-19 and related complications as compared to their younger counterparts. This reality, combined with pandemic-related lockdown and social distancing policies, has increased in-home isolation for older adults. This includes cancelling in-person healthcare appointments and conducting many appointments via tele-health. As older adults have had to quickly pivot to learning new technologies, little is known about their experiences with navigating virtual healthcare during the pandemic. Therefore, this qualitative study aims to address that gap. One-on-one interviews (N=29) were conducted with older adults (Mean age=71.5; 86% female) via phone/Zoom. Participants were asked about their healthcare experiences during the pandemic and the role technology played. Interviews were transcribed and thematically analyzed using Nvivo12 software. Findings demonstrate that participants used technology to schedule medical appointments, engage in virtual visits with their providers, set reminders to take medications, and undertake their daily exercise routine. Post-lockdown, some participants preferred in-person visits due to the nature of their diagnosis, personal preference, or unfamiliarity with the needed technology. Older adults encountered challenges including cancelled appointments, miscommunication with providers, and lack of skill to use technologies. Cancellation of appointments and postponement of treatments affected the health of some of the participants. Implications of this research can inform tele-health approaches with older patients, as well as provider communication and coordination of care. Leveraging technology for preventative health approaches can also assist older adults in ongoing health maintenance and promote well-being.

Child programs infusion of the sportlife club system children's activity

Modern life is quite comfortable. Less and less physical effort a human spends to meet every day needs. A sedentary lifestyle is becoming habitual for many, but it is important to remember that a young body needs exercise to grow and develop. In order to maintain good physical shape, you should do exercise. As a result, physical qualities develop: endurance, strength, agility, speed, flexibility. First of all physical activity improves not only the physical form, but also promotes the harmonious development of the child, strengthening his health. It is easier to raise a healthy child it quickly acquires the necessary skills and abilities, better adapts to changes in environmental conditions. It is easier to raise a healthy child, which quickly acquires the necessary skills and abilities, better adapts to changes in environmental conditions. An active healthy child is always strong and cheerful. Insufficient motor activity, vice versa, leads to weakness, weakens the body and its resistance to various diseases. Hypodynamia has an negatively affects mental development, reduces efficiency. This indicates a close relationship between mental and physical development. Daily exercise, participation in moving games; long walks are necessary condition for creating an optimal motor that meets the biological needs of the child's body.

Application of nutraceuticals in managing osteoarthritis and osteoporosis

Background: Several health problems, especially musculoskeletal disorders, are caused by dif-ferences in work cultures and human lifestyles around the world. While the conventional ap-proach to treating such conditions emphasizes a balanced work-life balance and daily exercise, nutraceuticals have proven to be successful. Nutraceuticals are dietary compounds that help sus-tain cartilage metabolism homeostasis, reducing articular pain. Dietary intake of a variety of nutraceuticals is thought to be essential for controlling and, more specifically, preventing osteoar-thritis and osteoporosis. Objective: The current article offers a succinct overview in which data was gathered and searched using specific key-terms related to nutraceuticals, osteoarthritis, and osteoporosis that were available in public domains for analysis and evaluation. Method: The current write-up offers a concise summary of disease and its relevance as to how nutraceuticals are helpful, based on the defined findings and their interpretation. The present re-view also discusses the existing literature, patents, and current studies in the era of nutraceuticals for osteoarthritis and osteoporosis treatment, offering a rational basis for further investigation and research. Result: This article discusses a wide variety of nutraceuticals with possible uses for osteoarthritis and osteoporosis patients. An analysis revealed that nutraceuticals' efficacy has been established. However, further study and investigation are needed to determine their protection. Conclusion: As a result of this analysis, it was concluded that more innovation and technology transfer were required. It was also concluded that greater industry-academic collaboration was required to begin more effective research in the treatment of osteoarthritis and osteoporosis with nutraceuticals.

Lifestyle Modification Improves Physical and Mental Health in Elderly Participants: Observational Study in a Controlled Environment

A 60-day observational study was conducted to evaluate how lifestyle modification principles relying upon a customized regimen of aerobic and muscle strength exercise, a plant-based diet and meditative stress reduction techniques may improve physical endurance and strength, mental health, and reverse normal aging associated with the average American lifestyle. All enrolled participants were generally in good health respective to their age. Several subjects had overlapping mild medical conditions. The results demonstrate that the intervention of a customized lifestyle modification regimen of regular daily exercise, a plant-based diet, and daily stress reduction practices, such as meditation and yoga, may provide a viable and beneficial preventative strategy as an anti-aging and wellness model to increase the physical and mental health of elderly men and women.

Factors associated with health intentions and behaviour among health checkup participants in Japan

Health intentions and behaviours are essential for improving the health of individuals and society. This study used cross-sectional data from 20,155 health checkup participants in the Yamagata study to identify factors associated with health intentions and behaviours. Information regarding the current level of health intentions and behaviours was collected using a baseline survey questionnaire. Participants were categorised into three groups: having no intention (no intention), having intentions to improve but not acting on them (intention), and already active (action). The associations between background factors and the presence/absence of health intentions and behaviours were assessed using logistic regression analysis. Of the participants, 35.4%, 37.7%, and 26.9% belonged to the no intention, intention, and action groups, respectively. Multivariate analysis revealed that the factors associated with health intentions were being young, being female, longer duration of education, higher body mass index and abdominal circumference, diabetes, and dyslipidaemia. The factors associated with health behaviours were being older and male, not consuming alcohol, not smoking, performing daily exercise, and having diabetes. These results indicate that health guidance considering background factors, including age, gender, education, and comorbidities, may be useful for effectively promoting health intentions and health behaviours in the Japanese population.

Daily Exercise and Alcohol Use Among Young Adult College Students

The present study examined associations between exercise and alcohol use at the between- and within-person levels, including temporal sequencing and the impact of gender. Participants were 221 college students that completed an online survey and 14 daily surveys assessing their daily exercise and alcohol use. Individuals who reported higher exercise scores also consumed more alcohol, on average. On days when individuals reported consuming fewer drinks than usual, they also reported greater exercise scores. Individuals reported lower exercise scores following a day with heavier alcohol use than usual or a day with heavy episodic drinking. Exercise was unassociated with next-day alcohol use. There were mixed findings on the impact of gender. Exercise may have a more proximal influence on drinking. Exercise interventions for alcohol use could target days with higher probabilities of drinking to reduce levels of alcohol use among college students.

Avoiding isolation: Physical activity for persons with disabilities and Covid-19

It was aimed in this article to draw attention to the following issues: the importance of issuing guidelines on what countries can or should do in order for individuals with disabilities to maintain their daily exercises or physical activity routines, and informing the public about it; the importance of considering the needs of a person with disabilities in emergency preparedness and response plans of the countries affected by the Covid-19 pandemic; the importance of the dissemination of public health messages in plain language and accessible formats through all mass media channels; the importance of providing psychosocial support to persons with disabilities and their families; and, the importance of strengthening support networks for persons with disabilities. In the research, the literature on Covid-19 and physical activity in disabilities published in 2020 was scanned via Pubmed and Google Scholar, and the study was designed as a review. Analysis of the related literature showed that it is important to develop a habit of performing regular physical activity in disabilities and to continue these activities especially during the pandemic period. In this review, persons with disabilities should be informed about what they can or should do to maintain their daily exercise or physical activity routines.

Determination of Motivating Factors of Urban Forest Visitors through Latent Dirichlet Allocation Topic Modeling

Despite the unique characteristics of urban forests, the motivating factors of urban forest visitors have not been clearly differentiated from other types of the forest resource. This study aims to identify the motivating factors of urban forest visitors, using latent Dirichlet allocation (LDA) topic modeling based on social big data. A total of 57,449 cases of social text data from social blogs containing the keyword “urban forest” were collected from Naver and Daum, the major search engines in South Korea. Then, 17,229 cases were excluded using morpheme analysis and stop word elimination; 40,110 cases were analyzed to identify the motivating factors of urban forest visitors through LDA topic modeling. Seven motivating factors—“Cafe-related Walk”, “Healing Trip”, “Daily Leisure”, “Family Trip”, “Wonderful View”, “Clean Space”, and “Exhibition and Photography”—were extracted; each contained five keywords. This study elucidates the role of forests as a place for healing, leisure, and daily exercise. The results suggest that efforts should be made toward developing various programs regarding the basic functionality of urban forests as a natural resource and a unique place to support a diversity of leisure and cultural activities.