The Clinical Value of Extracorporeal Shock Wave Therapy Evaluated by Contrast-Enhanced Ultrasound for Noninfectious Nonunion

2021 ◽  
Vol 11 (8) ◽  
pp. 2080-2085
Author(s):  
Yinfeng Hu ◽  
Xuewen Jia ◽  
Yingchun Zhu ◽  
Youfeng Xu ◽  
Minhua Guo ◽  
...  

Objectives: The aim of this study was to investigate the clinical value of Contrast-enhanced ultrasound (CEUS) in evaluating Extracorporeal shock wave therapy (ESWT) for noninfectious nonunion. Methods: Thirty-eight patients with long bone nonunion fractures whose were treated in our hospital from October 2016 to October 2019 were included (20 males and 18 females). The patients received ESWT once a week for 12 consecutive weeks. CEUS was performed before and after the first ESWT session. According to the ratio of the perfusion area to the callus area, neovascular blood flow observed in CEUS was divided into 4 grades: grade 0 = 0%, grade 1 = 0–30%, grade 2 = 30–70% and grade 3 = 70–100%. The peak values of microbubbles perfusion in the callus area were recorded before and after ESWT. Each patient was followed up for 12 months to record the healing time. Nonunion over 12 months was considered a nonhealing fracture. To compare the ultrasonic data before and after ESWT, paired T test was used and the correlation between the ultrasonic data and the nonunion healing time, the pearson analysis was used. Results: Of the 38 patients, 35 patients achieved nonunion healing. The healing time ranged from 5 months to 12 months. Among the 38 patients, 24 patients had a microvascular health score of 0 points and 14 patients had a score of 1 point before treatment. After therapy, the neovascular health score was 0, 1, 2 and 3 in 5, 10, 15 and 8 patients, respectively. There was a statistically significant difference before and after treatment (P < 0.05). The peak value of microbubbles perfusion in the fracture site after ESWT was significantly higher than that before ESWT (P < 0.05). The greater of difference, the shorter of healing time. Conclusion: Under the supervision of CEUS, the changes in microvascular perfusion of noninfectious nonunion patients before and after ESWT effectively reflected the therapeutic effect. CEUS could predict the ESWT on bone nonunion at an early stage. Level of evidence: Level III.

Urologiia ◽  
2019 ◽  
Vol 3_2019 ◽  
pp. 43-49
Author(s):  
V.I. Rudenko Rudenko ◽  
L.M. Rapoport Rapoport ◽  
Yu.L. Demidko Demidko ◽  
L.S. Demidko Demidko ◽  
G.S. Inoyatov Inoyatov ◽  
...  

Health of Man ◽  
2021 ◽  
pp. 31-34
Author(s):  
Ihor Gorpynchenko ◽  
Kamil Nurimanov ◽  
Olena Nedogonova ◽  
Tetiana Poroshina ◽  
Viktoriia Savchenko ◽  
...  

Extracorporeal shock wave therapy (ESWT) is a non-pharmacological, non-invasive procedure   for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The objective: to evaluate the dynamics and relationship of clinical symptoms and ejaculate cytokine concentrations during the use of ESWT in the treatment of patients with CP/CPPS. Materials and methods. The study included 37 patients aged 18–45 years with CP/CPPS who received ESWT in the projection of the prostate and seminal vesicles. Symptoms of prostatitis were assessed by the NIH-CPSI scale, and ejaculate cytokines were assessed by ELISA before and after treatment. To analyze the results of treatment, patients with a significant reduction in the activity of prostatitis symptoms (by 6 or more points on the NIH-CPSI scale) were grouped into subgroup A. Patients with insufficient efficacy were grouped into subgroup B. Results. After treatment, 21 (57%) patients significantly reduced the intensity of prostatitis symptoms (subgroup A). Patients with insufficient efficacy were grouped into subgroup B. The content of proinflammatory cytokine – interleukin-1β ejaculate significantly (p<0.05) increased only in these patients. In subgroup A, a significant correlation was found between the assessment of prostatitis symptoms on the NIH-CPSI scale and the concentration of interleukin-1β ejaculate (Spearman’s r=0.650; p<0.001 and r=0.735; p<0.001 before and after treatment, respectively). The concentration of the anti-inflammatory cytokine ejaculate (interleukin-10) increased significantly only in subgroup A (p<0.05). Conclusion. Extracorporeal shock wave therapy provides a significant reduction in the symptoms of prostatitis causing dosed minimal damage and inflammation of the prostate and seminal vesicles, associated with an increase in the level of interleukin-1β in the ejaculate.


2021 ◽  
pp. 15-16
Author(s):  
Saroj Yadav ◽  
Gautam Gupta ◽  
Jaya S. Radhwani

Thirty patients with symptomatic tennis elbow were included in this study according to the inclusion and exclusion criteria and informed consent was taken. The study aimed at comparing the effect of a single session of ESWTusing VAS, PRTEE and dynamometer. The assessments were done before and after the intervention (24hrs and 72 hrs.). This study concluded that ESWT is effective in improving pain, grip strength and functional status in case of tennis elbow


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