scholarly journals [Retracted] Combined treatment with extracorporeal shock‑wave therapy and bone marrow mesenchymal stem cell transplantation improves bone repair in a rabbit model of bone nonunion

2018 ◽  
Author(s):  
Tao Fan ◽  
Guozhi Huang ◽  
Wen Wu ◽  
Rong Guo ◽  
Qing Zeng
Keyword(s):  
Shock Wave ◽  
Bone Marrow ◽  
Bone Repair ◽  
Combined Treatment ◽  
Rabbit Model ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Mesenchymal Stem Cell Transplantation ◽  
Extracorporeal Shock Wave ◽  
Bone Nonunion

The Clinical Value of Extracorporeal Shock Wave Therapy Evaluated by Contrast-Enhanced Ultrasound for Noninfectious Nonunion

2021 ◽  
Vol 11 (8) ◽  
pp. 2080-2085
Author(s):  
Yinfeng Hu ◽  
Xuewen Jia ◽  
Yingchun Zhu ◽  
Youfeng Xu ◽  
Minhua Guo ◽  
...  
Keyword(s):  
Shock Wave ◽  
Extracorporeal Shock Wave Therapy ◽  
Healing Time ◽  
Contrast Enhanced Ultrasound ◽  
Shock Wave Therapy ◽  
Clinical Value ◽  
Extracorporeal Shock Wave ◽  
Contrast Enhanced ◽  
Before And After ◽  
Bone Nonunion

Objectives: The aim of this study was to investigate the clinical value of Contrast-enhanced ultrasound (CEUS) in evaluating Extracorporeal shock wave therapy (ESWT) for noninfectious nonunion. Methods: Thirty-eight patients with long bone nonunion fractures whose were treated in our hospital from October 2016 to October 2019 were included (20 males and 18 females). The patients received ESWT once a week for 12 consecutive weeks. CEUS was performed before and after the first ESWT session. According to the ratio of the perfusion area to the callus area, neovascular blood flow observed in CEUS was divided into 4 grades: grade 0 = 0%, grade 1 = 0–30%, grade 2 = 30–70% and grade 3 = 70–100%. The peak values of microbubbles perfusion in the callus area were recorded before and after ESWT. Each patient was followed up for 12 months to record the healing time. Nonunion over 12 months was considered a nonhealing fracture. To compare the ultrasonic data before and after ESWT, paired T test was used and the correlation between the ultrasonic data and the nonunion healing time, the pearson analysis was used. Results: Of the 38 patients, 35 patients achieved nonunion healing. The healing time ranged from 5 months to 12 months. Among the 38 patients, 24 patients had a microvascular health score of 0 points and 14 patients had a score of 1 point before treatment. After therapy, the neovascular health score was 0, 1, 2 and 3 in 5, 10, 15 and 8 patients, respectively. There was a statistically significant difference before and after treatment (P < 0.05). The peak value of microbubbles perfusion in the fracture site after ESWT was significantly higher than that before ESWT (P < 0.05). The greater of difference, the shorter of healing time. Conclusion: Under the supervision of CEUS, the changes in microvascular perfusion of noninfectious nonunion patients before and after ESWT effectively reflected the therapeutic effect. CEUS could predict the ESWT on bone nonunion at an early stage. Level of evidence: Level III.

scholarly journals Effectiveness of extracorporeal shock wave therapy in bone marrow edema syndrome of the hip

2014 ◽  
Vol 34 (11) ◽  
pp. 1513-1518 ◽  
Author(s):  
Cristina d’Agostino ◽  
Pietro Romeo ◽  
Vito Lavanga ◽  
Salvatore Pisani ◽  
Valerio Sansone
Keyword(s):  
Shock Wave ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Bone Marrow Edema Syndrome ◽  
Extracorporeal Shock Wave ◽  
Marrow Edema

scholarly journals High-energy focused extracorporeal shock wave therapy for bone marrow edema syndrome of the hip

Medicine ◽  
2020 ◽  
Vol 99 (16) ◽  
pp. e19747 ◽  
Author(s):  
Leilei Zhang ◽  
Yuzhi Cui ◽  
Dawei Liang ◽  
Jie Guan ◽  
Youwen Liu ◽  
...  
Keyword(s):  
Shock Wave ◽  
Bone Marrow ◽  
Bone Marrow Edema ◽  
Extracorporeal Shock Wave Therapy ◽  
High Energy ◽  
Shock Wave Therapy ◽  
Bone Marrow Edema Syndrome ◽  
Extracorporeal Shock Wave ◽  
Marrow Edema

Growth Factors in Bone Marrow Blood of the Mandible With Application of Extracorporeal Shock Wave Therapy

2016 ◽  
Vol 25 (5) ◽  
pp. 606-612 ◽  
Author(s):  
Jacqueline A. Pfaff ◽  
Birgit Boelck ◽  
Wilhelm Bloch ◽  
Georg-Hubertus Nentwig
Keyword(s):  
Shock Wave ◽  
Bone Marrow ◽  
Growth Factors ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Extracorporeal Shock Wave ◽  
Bone Marrow Blood

scholarly journals Extracorporeal shock wave therapy for bone marrow edema syndrome in patients with osteonecrosis of the femoral head: a retrospective cohort study

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Wenyi Zhao ◽  
Yuan Gao ◽  
Shouxiang Zhang ◽  
Zhang Liu ◽  
Lin He ◽  
...  
Keyword(s):  
Shock Wave ◽  
Bone Marrow ◽  
Cohort Study ◽  
Retrospective Cohort ◽  
Bone Marrow Edema ◽  
Extracorporeal Shock Wave Therapy ◽  
Shock Wave Therapy ◽  
Extracorporeal Shock Wave ◽  
Harris Score ◽  
Marrow Edema

Abstract Background There is now ample evidence suggesting that extracorporeal shock wave therapy (ESWT) can improve hip mobility and reduce pain in patients with osteonecrosis of the femoral head (ONFH). The ability of ESWT to cure bone marrow edema syndrome (BMES) in patients with ONFH, 12 weeks after the initial course of ESWT, needs to be verified further and more relevant clinical research-based evidence should be consolidated. This study aimed to evaluate the efficacy of ESWT for BMES caused by ONFH. Methods This retrospective cohort study included 67 patients with BMES caused by ONFH who were participating in a rehabilitation program as outpatients. Before and after ESWT, the area of femoral bone marrow edema was evaluated by magnetic resonance imaging (MRI), and the Harris score and Charnley score were evaluated as hip pain and function indicators. Results After ESWT, MRI revealed that the area of bone marrow edema decreased from 984.6 ± 433.2 mm2 to 189.7 ± 214.4 mm2 (P < 0.0001). The Harris score increased from 42.2 ± 9.1 to 77.7 ± 10.8 points (P < 0.0001). The Charnley score increased from 7.3 ± 1.4 to 12.0 ± 1.7 (P < 0.0001). ESWT was effective in treating BMES in 98.5% of the cases. Conclusions This study demonstrated that ESWT can effectively treat BMES caused by ONFH and can aid in pain relief and functional recovery in patients with ONFH. Thus, ESWT should be included in the classic physical therapy regimen for patients with ONFH and BMES.

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