Signal Amplification of Electrochemical ELISA for the Detection of Alpha-Fetoprotein Using Core–Shell Fe3O4@Au Nanoparticles as Labels

2012 ◽  
Vol 10 (3) ◽  
pp. 886-893 ◽  
Author(s):  
Haijuan Jin ◽  
Ning Gan ◽  
Jianguo Hou ◽  
Futao Hu ◽  
Yuting Cao ◽  
...  
Lab on a Chip ◽  
2020 ◽  
Vol 20 (4) ◽  
pp. 717-721 ◽  
Author(s):  
Zainab H. Al Mubarak ◽  
Gayan Premaratne ◽  
Asantha Dharmaratne ◽  
Farshid Mohammadparast ◽  
Marimuthu Andiappan ◽  
...  

We report a large surface plasmon signal amplification for a double hybridization microarray chip assembly that bridges localized gold and detection probe-carrying-core/shell Fe3O4@Au nanoparticles to enable detection of 80 aM miRNA-155 in solution.


Author(s):  
Kerry O-Connell ◽  
John R Monnier ◽  
John Regalbuto

In an effort to stabilize gold nanoparticles which sinter rapidly in a highly corrosive chemical environment, the hydrochlorination of acetylene, bimetallic Ru@Au and Pt@Au core-shell catalysts were prepared by anchoring...


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chin-Wei Lin ◽  
Jian-Ming Chen ◽  
You-Jun Lin ◽  
Ling-Wei Chao ◽  
Sin-Yi Wei ◽  
...  

Abstract Recently, gold-coated magnetic nanoparticles have drawn the interest of researchers due to their unique magneto-plasmonic characteristics. Previous research has found that the magneto-optical Faraday effect of gold-coated magnetic nanoparticles can be effectively enhanced because of the surface plasmon resonance of the gold shell. Furthermore, gold-coated magnetic nanoparticles are ideal for biomedical applications because of their high stability and biocompatibility. In this work, we synthesized Fe3O4@Au core-shell nanoparticles and coated streptavidin (STA) on the surface. Streptavidin is a protein which can selectively bind to biotin with a strong affinity. STA is widely used in biotechnology research including enzyme-linked immunosorbent assay (ELISA), time-resolved immunofluorescence (TRFIA), biosensors, and targeted pharmaceuticals. The Faraday magneto-optical characteristics of the biofunctionalized Fe3O4@Au nanoparticles were measured and studied. We showed that the streptavidin-coated Fe3O4@Au nanoparticles still possessed the enhanced magneto-optical Faraday effect. As a result, the possibility of using biofunctionalized Fe3O4@Au nanoparticles for magneto-optical biomedical assays should be explored.


2004 ◽  
Vol 397 (1-3) ◽  
pp. 128-132 ◽  
Author(s):  
Xing-bin Yan ◽  
Tao Xu ◽  
Shan Xu ◽  
Gang Chen ◽  
Qun-ji Xue ◽  
...  

2007 ◽  
Vol 2007 (8) ◽  
pp. 1128-1134 ◽  
Author(s):  
Liangbao Yang ◽  
Yuhua Shen ◽  
Anjian Xie ◽  
Jianjun Liang ◽  
Jinmiao Zhu ◽  
...  

2005 ◽  
Vol 11 (S02) ◽  
Author(s):  
Z Y Li ◽  
J Yuan ◽  
Y Chen ◽  
R Palmer ◽  
J Wilcoxon

2006 ◽  
Vol 18 (4) ◽  
pp. 960-967 ◽  
Author(s):  
Sung-Jin Cho ◽  
Ahmed M. Shahin ◽  
Gary J. Long ◽  
Joseph E. Davies ◽  
Kai Liu ◽  
...  

RSC Advances ◽  
2017 ◽  
Vol 7 (13) ◽  
pp. 7469-7475 ◽  
Author(s):  
Ryeri Lee ◽  
Yogeenth Kumaresan ◽  
Sei Young Yoon ◽  
Soong Ho Um ◽  
Il Keun Kwon ◽  
...  

In this study, we designed core/shell nanostructures (CSNs) of silicon dioxide (SiO2)/titanium dioxide (TiO2), which were decorated with gold (Au) nanoparticles (NPs), to activate the visible light-driven photocatalytic reaction.


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