Plasmonic nucleotide hybridization chip for attomolar detection: localized gold and tagged core/shell nanomaterials

Lab on a Chip ◽  
2020 ◽  
Vol 20 (4) ◽  
pp. 717-721 ◽  
Author(s):  
Zainab H. Al Mubarak ◽  
Gayan Premaratne ◽  
Asantha Dharmaratne ◽  
Farshid Mohammadparast ◽  
Marimuthu Andiappan ◽  
...  

We report a large surface plasmon signal amplification for a double hybridization microarray chip assembly that bridges localized gold and detection probe-carrying-core/shell Fe3O4@Au nanoparticles to enable detection of 80 aM miRNA-155 in solution.

2012 ◽  
Vol 10 (3) ◽  
pp. 886-893 ◽  
Author(s):  
Haijuan Jin ◽  
Ning Gan ◽  
Jianguo Hou ◽  
Futao Hu ◽  
Yuting Cao ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1728
Author(s):  
Joshua Fernandes ◽  
Sangmo Kang

The near-field enhancement and localized surface plasmon resonance (LSPR) on the core-shell noble metal nanostructure surfaces are widely studied for various biomedical applications. However, the study of the optical properties of new plasmonic non-spherical nanostructures is less explored. This numerical study quantifies the optical properties of spherical and non-spherical (prolate and oblate) dimer nanostructures by introducing finite element modelling in COMSOL Multiphysics. The surface plasmon resonance peaks of gold nanostructures should be understood and controlled for use in biological applications such as photothermal therapy and drug delivery. In this study, we find that non-spherical prolate and oblate gold dimers give excellent tunability in a wide range of biological windows. The electromagnetic field enhancement and surface plasmon resonance peak can be tuned by varying the aspect ratio of non-spherical nanostructures, the refractive index of the surrounding medium, shell thickness, and the distance of separation between nanostructures. The absorption spectra exhibit considerably greater dependency on the aspect ratio and refractive index than the shell thickness and separation distance. These results may be essential for applying the spherical and non-spherical nanostructures to various absorption-based applications.


RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 2733-2743
Author(s):  
Parisa Talebi ◽  
Harishchandra Singh ◽  
Ekta Rani ◽  
Marko Huttula ◽  
Wei Cao

Surface plasmonic resonance enabled Ni@NiO/NiCO3 core–shell nanostructures as promising photocatalysts for hydrogen evolution under visible light.


Author(s):  
Kerry O-Connell ◽  
John R Monnier ◽  
John Regalbuto

In an effort to stabilize gold nanoparticles which sinter rapidly in a highly corrosive chemical environment, the hydrochlorination of acetylene, bimetallic Ru@Au and Pt@Au core-shell catalysts were prepared by anchoring...


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chin-Wei Lin ◽  
Jian-Ming Chen ◽  
You-Jun Lin ◽  
Ling-Wei Chao ◽  
Sin-Yi Wei ◽  
...  

Abstract Recently, gold-coated magnetic nanoparticles have drawn the interest of researchers due to their unique magneto-plasmonic characteristics. Previous research has found that the magneto-optical Faraday effect of gold-coated magnetic nanoparticles can be effectively enhanced because of the surface plasmon resonance of the gold shell. Furthermore, gold-coated magnetic nanoparticles are ideal for biomedical applications because of their high stability and biocompatibility. In this work, we synthesized Fe3O4@Au core-shell nanoparticles and coated streptavidin (STA) on the surface. Streptavidin is a protein which can selectively bind to biotin with a strong affinity. STA is widely used in biotechnology research including enzyme-linked immunosorbent assay (ELISA), time-resolved immunofluorescence (TRFIA), biosensors, and targeted pharmaceuticals. The Faraday magneto-optical characteristics of the biofunctionalized Fe3O4@Au nanoparticles were measured and studied. We showed that the streptavidin-coated Fe3O4@Au nanoparticles still possessed the enhanced magneto-optical Faraday effect. As a result, the possibility of using biofunctionalized Fe3O4@Au nanoparticles for magneto-optical biomedical assays should be explored.


2004 ◽  
Vol 397 (1-3) ◽  
pp. 128-132 ◽  
Author(s):  
Xing-bin Yan ◽  
Tao Xu ◽  
Shan Xu ◽  
Gang Chen ◽  
Qun-ji Xue ◽  
...  

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