scholarly journals Association of 24-Hour Intraocular Pressure Fluctuation With Corneal Hysteresis and Axial Length in Untreated Chinese Primary Open-Angle Glaucoma Patients

2020 ◽  
Vol 9 (12) ◽  
pp. 25
Author(s):  
Yaping Yang ◽  
Tsz Kin Ng ◽  
Li Wang ◽  
Na Wu ◽  
Ming Xiao ◽  
...  
2013 ◽  
Vol 22 (4) ◽  
pp. 290-293 ◽  
Author(s):  
Masato Matsuoka ◽  
Akira Ando ◽  
Keizo Minamino ◽  
Kayako Matsuyama ◽  
Chieko Shima ◽  
...  

Eye ◽  
2015 ◽  
Vol 30 (3) ◽  
pp. 362-368 ◽  
Author(s):  
S Srinivasan ◽  
N S Choudhari ◽  
M Baskaran ◽  
R J George ◽  
B Shantha ◽  
...  

2009 ◽  
Vol 18 (9) ◽  
pp. 689-691 ◽  
Author(s):  
Kazuyuki Hirooka ◽  
Hirokazu Takenaka ◽  
Tetsuya Baba ◽  
Mai Takagishi ◽  
Masanori Mizote ◽  
...  

2021 ◽  
Author(s):  
Moataz Sallam ◽  
Mervat E. Elghareib

Abstract Purpose: To introduce a new method for estimation of the target intraocular pressure (TIOP) in naïve eyes with early primary open angle glaucoma (POAG) using Corneal hysteresis (CH) and corneal resistance factor (CRF).Methods: A prospective quasi-experimental study was conducted on naïve 90 eyes of 45 patients who were newly diagnosed with early primary open angle glaucoma (POAG). They were compared to 72 eyes of 36 normal subjects. The TIOP was determined for each eye. The IOP Goldmann (IOPg), IOP corneal-compensated (IOPcc), CH and CRF were estimated by Ocular Response Analyzer (ORA, Reichert) device. Measurements were taken for each patient prior to treatment and after 1, 3, 6, 9 and 12 months of receiving medications; either monotherapy or combination therapy.Results: For all patients, there was a significant negative correlation (p < 0.05) between IOP, either IOPg or IOPcc, and CH while a significant positive relationship (p < 0.05) existed between IOP and CRF. For patients with early POAG, The CH was significantly increased (p ≤ 0.001) while CRF was significantly decreased (p ≤ 0.001) when TIOP was achieved. At IOP levels higher than TIOP, CH value was lower than CRF with a significant negative correlation between them in contrast to controls. This correlation was reversed on reaching TIOP and CH values became higher than CRF similar to controls.Conclusion: CH, CRF and IOP measured by ORA can be used for TIOP estimation. This provides us with a guide for assessing the effectiveness of medications introduced to patients with POAG.


Author(s):  
E. N. Simakova ◽  
O. V. Stenkova

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.


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