Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

Journal of Clinical Investigation ◽

10.1172/jci71197 ◽

2013 ◽

Vol 123 (8) ◽

pp. 3634-3634

Author(s):

Cristian Bellodi ◽

Maria Rosa Lidonnici ◽

Ashley Hamilton ◽

G. Vignir Helgason ◽

Angela Rachele Soliera ◽

...

Keyword(s):

Stem Cells ◽

Cell Death ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Faculty Opinions recommendation of Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1161294.621787 ◽

2009 ◽

Author(s):

Xiaoyan Jiang

Keyword(s):

Stem Cells ◽

Cell Death ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Reduced intensity chemotherapy with tyrosine kinase inhibitor and blinatumomab in a pediatric patient with Philadelphia chromosome‐positive ALL and mechanical heart valves

Pediatric Blood & Cancer ◽

10.1002/pbc.28924 ◽

2021 ◽

Author(s):

Richa Sharma ◽

Clifford Takemoto ◽

Benjamin Waller ◽

Ashley Holland ◽

Ching‐Hon Pui ◽

...

Keyword(s):

Tyrosine Kinase ◽

Pediatric Patient ◽

Heart Valves ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Mechanical Heart Valves ◽

Reduced Intensity ◽

Tyrosine kinase inhibitor therapy or transplant in children with Philadelphia chromosome-positive acute lymphoblastic leukaemia: striking the balance

The Lancet Haematology ◽

10.1016/s2352-3026(18)30181-9 ◽

2018 ◽

Vol 5 (12) ◽

pp. e606-e607 ◽

Cited By ~ 2

Author(s):

Oliver Ottmann

Keyword(s):

Tyrosine Kinase ◽

Acute Lymphoblastic Leukaemia ◽

Lymphoblastic Leukaemia ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Inhibitor Therapy ◽

Tyrosine Kinase Inhibitor Therapy ◽

Abstract 4763: The tyrosine kinase inhibitor axitinib targets T315I gatekeeper-mutant Philadelphia chromosome-positive leukemiasin vitroandin vivo

10.1158/1538-7445.am2014-4763 ◽

2014 ◽

Author(s):

Tea Pemovska ◽

Mika Kontro ◽

Gretchen A. Repasky ◽

Kimmo Porkka ◽

Krister Wennerberg

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Tyrosine kinase inhibitor prophylaxis after transplant for Philadelphia chromosome‐positive acute lymphoblastic leukemia

Cancer Science ◽

10.1111/cas.14167 ◽

2019 ◽

Vol 110 (10) ◽

pp. 3255-3266 ◽

Cited By ~ 12

Author(s):

Yu Akahoshi ◽

Satoshi Nishiwaki ◽

Shuichi Mizuta ◽

Kazuteru Ohashi ◽

Naoyuki Uchida ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Lymphoblastic Leukemia ◽

Philadelphia Chromosome ◽

The Impact of Smoking on Relapse and Survival in Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor

Clinical Lymphoma Myeloma & Leukemia ◽

10.1016/j.clml.2019.07.014 ◽

2019 ◽

Vol 19 ◽

pp. S180

Author(s):

Koji Sasaki ◽

Hagop Kantarjian ◽

Guillaume Richard-Carpentier ◽

Farhad Ravandi ◽

Nicholas Short ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Lymphoblastic Leukemia ◽

Intensive Therapy ◽

Philadelphia Chromosome ◽

Newly Diagnosed ◽

The Impact ◽

ABL-specific tyrosine kinase inhibitor imatinib as salvage therapy in a child with Philadelphia chromosome-positive acute mixed lineage leukemia (AMLL)

Leukemia ◽

10.1038/sj.leu.2402520 ◽

2002 ◽

Vol 16 (7) ◽

pp. 1393-1395 ◽

Cited By ~ 5

Author(s):

B Selle ◽

C Bär ◽

S Hecker ◽

U Schmidt-Rohr ◽

S Viehmann ◽

...

Keyword(s):

Tyrosine Kinase ◽

Salvage Therapy ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Mixed Lineage Leukemia ◽

Considerations in the Management of Patients With Philadelphia Chromosome–Positive Chronic Myeloid Leukemia Receiving Tyrosine Kinase Inhibitor Therapy

Journal of Clinical Oncology ◽

10.1200/jco.2010.33.9176 ◽

2011 ◽

Vol 29 (12) ◽

pp. 1512-1516 ◽

Cited By ~ 24

Author(s):

Hagop Kantarjian ◽

Jorge Cortes

Keyword(s):

Chronic Myeloid Leukemia ◽

Tyrosine Kinase ◽

Myeloid Leukemia ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Inhibitor Therapy ◽

Tyrosine Kinase Inhibitor Therapy ◽

Low or undetectable numbers of Philadelphia chromosome-positive leukemic stem cells (Ph+CD34+CD38neg) in chronic myeloid leukemia patients in complete cytogenetic remission after tyrosine kinase inhibitor therapy

Leukemia ◽

10.1038/leu.2009.190 ◽

2009 ◽

Vol 24 (1) ◽

pp. 219-222 ◽

Cited By ~ 13

Author(s):

S Mustjoki ◽

P Rohon ◽

K Rapakko ◽

S Jalkanen ◽

P Koskenvesa ◽

...

Keyword(s):

Stem Cells ◽

Chronic Myeloid Leukemia ◽

Tyrosine Kinase ◽

Myeloid Leukemia ◽

Kinase Inhibitor ◽

Philadelphia Chromosome ◽

Leukemic Stem Cells ◽

Tyrosine Kinase Inhibitor Therapy ◽

Cytogenetic Remission