Results of the dexamethasone suppression test in psychiatric patients with and without weight loss

1985 ◽  
Vol 142 (2) ◽  
pp. 246-248 ◽  
1989 ◽  
Vol 34 (7) ◽  
pp. 707-709 ◽  
Author(s):  
Sidney H. Kennedy ◽  
Paul E. Garfinkel ◽  
Stephen Stokl ◽  
Carrol A. Whynot

In a prospective study of 28 subjects with major depression, weight was significantly related to nonsuppression in the dexamethasone suppression test (DST) on admission and seven days later. However, changes in weight between these two times did not alter the DST status.


1984 ◽  
Vol 13 (4) ◽  
pp. 353-354 ◽  
Author(s):  
Florian Holsboer ◽  
Michael Philipp ◽  
Armand Gerken

1984 ◽  
Vol 145 (1) ◽  
pp. 88-90 ◽  
Author(s):  
Alec Coppen ◽  
Janet Harwood ◽  
Keith Wood

SummaryThe dexamethasone suppression test (DST) was carried out on 143 patients with a major depressive disorder, who were classified into those with a history of weight loss (n = 89) and those without (n = 54). Seventy-three per cent of patients with weight loss and 61% of patients without had an abnormal DST; this difference was not statistically significant. Of the patients receiving prophylactic lithium therapy, 13 were found to have changed their DST status on retesting after a period of 14 months, but there was no significant difference in their weight. It is concluded that weight loss is not a necessary condition for an abnormal DST in depressive illness.


1988 ◽  
Vol 152 (5) ◽  
pp. 654-656 ◽  
Author(s):  
G. O'Brien ◽  
F. Hassanyeh ◽  
A. Leake ◽  
K. Schapira ◽  
M. White ◽  
...  

In a study of the dexamethasone suppression test (DST) in patients with bulimia nervosa, a non-suppression rate of about 50% was found. The only clinical correlates of DST non-suppression were a previous history of weight loss and/or of anorexia nervosa. These results suggest that DST non-suppression in these subjects may be a trait rather than a state marker of anorexia nervosa.


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