scholarly journals Improvement in Social Competence With Short-Term Atypical Antipsychotic Treatment: A Randomized, Double-Blind Comparison of Quetiapine Versus Risperidone for Social Competence, Social Cognition, and Neuropsychological Functioning

2006 ◽  
Vol 163 (11) ◽  
pp. 1918-1925 ◽  
Author(s):  
Philip D. Harvey ◽  
Thomas L. Patterson ◽  
Larry S. Potter ◽  
Kate Zhong ◽  
Martin Brecher
Keyword(s):  
Social Cognition ◽  
Social Competence ◽  
Atypical Antipsychotic ◽  
Neuropsychological Functioning ◽  
Antipsychotic Treatment ◽  
Short Term ◽  
Double Blind ◽  
Blind Comparison

Absence of regional brain volume change in schizophrenia associated with short-term atypical antipsychotic treatment

2008 ◽  
Vol 98 (1-3) ◽  
pp. 29-39 ◽  
Author(s):  
Robert K. McClure ◽  
Khary Carew ◽  
Stacy Greeter ◽  
Emily Maushauer ◽  
Grant Steen ◽  
...  
Keyword(s):  
Atypical Antipsychotic ◽  
Volume Change ◽  
Brain Volume ◽  
Antipsychotic Treatment ◽  
Short Term ◽  
Regional Brain ◽  
Regional Brain Volume

DOUBLE-BLIND COMPARISON OF IBUPROFEN AND PHENYLBUTAZONE IN THE SHORT-TERM TREATMENT OF RHEUMATOID ARTHRITIS

Rheumatology ◽  
1973 ◽  
Vol 12 (2) ◽  
pp. 68-73 ◽  
Author(s):  
K. PAVELKA ◽  
A. SUSTA ◽  
O. VOJTÍŠEK ◽  
A. BREMOVÁ ◽  
D. KAŇKOVÁ ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Double Blind ◽  
Blind Comparison

Atypical (second generation) antipsychotic treatment response in very late-onset schizophrenia-like psychosis

2010 ◽  
Vol 23 (5) ◽  
pp. 742-748 ◽  
Author(s):  
Jamie Scott ◽  
Blaine S. Greenwald ◽  
Elisse Kramer ◽  
Mitchell Shuwall
Keyword(s):  
Treatment Response ◽  
Atypical Antipsychotic ◽  
Second Generation ◽  
Psychotic Disorders ◽  
Age Of Onset ◽  
Late Onset ◽  
Antipsychotic Treatment ◽  
Double Blind ◽  
Positive Treatment ◽  
Second Generation Antipsychotic

ABSTRACTIntroduction: Symptom amelioration in older patients with very late onset schizophrenia-like psychosis (VLOSLP) is often difficult, with limited psychotropic response reports yielding variable findings. Information about atypical (second generation) antipsychotic use in this population is scant.Methods: A consecutive sample of geriatric psychiatry outpatients and inpatients with psychotic disorders were retrospectively identified over a 31-month period based on systematic information abstraction from an electronic medical record (e-record). After exclusion criteria were applied, 8/138 outpatients and 13/362 inpatients met inclusion criteria for VLOSLP and had been naturalistically treated with an atypical antipsychotic during hospitalization or nine months of outpatient care. Mandatorily completed e-record standardized symptom severity response ratings were converted into positive treatment response thresholds.Results: 38% of outpatients and 77% of inpatients (mean age = 76 years for both groups; mean age of onset of psychosis = 70 years for outpatients and 74 years for inpatients) met criteria for positive treatment response to an atypical antipsychotic (either aripiprazole, olanzapine, quetiapine, or risperidone) with sign/symptom amelioration, rather than eradication.Conclusions: Various atypical antipsychotics at geriatric doses yielded a positive treatment response in nearly two-thirds of VLOSLP patients. Patients with less chronic, more severe symptoms responded at a higher rate. Prospective, double-blind, placebo-controlled trials with representative subject samples are needed to validate these preliminary findings.

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