Antibiotic Prophylaxis in Patients Undergoing Open Mesh Repair of Inguinal Hernia: A Meta-Analysis

2012 ◽  
Vol 78 (3) ◽  
pp. 359-365 ◽  
Author(s):  
Yuan Yin ◽  
Turun Song ◽  
Banghua Liao ◽  
Qian Luo ◽  
Zongguang Zhou
Keyword(s):  
Inguinal Hernia ◽  
Hernia Repair ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Mesh Repair ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Site Infection ◽  
Open Mesh Repair ◽  
Open Mesh

The use of antibiotic prophylaxis in hernia repair is still under debate. The aim of this meta-analysis was to assess the effect of antibiotic prophylaxis in patients undergoing open mesh repair of inguinal hernia with respect to incidence of postoperative surgical site infection (SSI). A literature search was conducted in databases of MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials. Study selection, data extraction, quality assessment, and meta-analysis were conducted according to the recommendations by Cochrane collaboration. Nine randomized controlled trials were included. Incidence of surgical site infection was 39/1642 (2.38%) in the antibiotic group and 70/1676 (4.18%) in the control group. Antibiotics showed a protective effect in preventing SSI after mesh inguinal hernia repair (odds ratio: 0.61, 95% confidence interval: 0.40–0.92, I2: 0%). Antibiotic prophylaxis did reduce the incidence of SSI in hernia patients undergoing mesh hernioplasty. The cost effectiveness of antibiotic prophylaxis needs further evaluation.

scholarly journals Effect of single dose pre-operative antibiotic prophylaxis versus conventional antibiotic therapy in patients undergoing lichtenstein tension free mesh repair

2017 ◽  
Vol 4 (2) ◽  
pp. 738
Author(s):  
Madhu B. S. ◽  
Shashi Kumar H. B. ◽  
Naveen Kumar Reddy M. ◽  
Abilash V. Reddy ◽  
Sangeetha Kalabhairav
Keyword(s):  
Single Dose ◽  
Inguinal Hernia ◽  
Side Effects ◽  
Hernia Repair ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Mesh Repair ◽  
Control Group ◽  
Site Infection ◽  
Tension Free

Background: Rational use of antibiotic is important as injudicious use can adversely affect the patient, cause emergence of antibiotic resistance and increase the cost of health care. The efficacy of antibiotic prophylaxis in preventing surgical site infection in patients undergoing Lichtenstein tension free inguinal hernia repair still remains controversial.Methods: A randomized controlled trial was conducted in patients undergoing lichtenstein tension free inguinal hernia repair between January 2015 to June 2016, and the results were compared with the control group in whom, conventional antibiotics were given for 7 days . All patients in study group undergoing surgery were given 400 mg parenteral ciprofloxacin 30 min prior to surgery. In the control group, the patients were given 2 days parenteral ciprofloxacin 400 mg twice a day and the next 5 days the same antibiotics were given in oral route, after surgery. Total 100 patients were randomized to 50 each group. The outcome in terms of duration of surgery, surgical site infection, cost and antibiotic side effects were then compared.Results: The duration of the hospital stay, cost and side effects are significantly higher in the control group patients. Antibiotic side effects (P < 0.05) were high for control group. The infection rate was same in both the groups. There was no significant difference in terms of infection rate among two groups.Conclusions: This study concludes that prophylactic single-dose antibiotic is effective in preventing surgical site infection and is cost-effective in patients undergoing lichtenstein tension free mesh repair.

scholarly journals The Role of Antibiotic Prophylaxis in Prevention of Wound Infection After Lichtenstein Open Mesh Repair of Primary Inguinal Hernia

2004 ◽  
Vol 240 (6) ◽  
pp. 955-961 ◽  
Author(s):  
Theo J. Aufenacker ◽  
Dirk van Geldere ◽  
Taco van Mesdag ◽  
Astrid N. Bossers ◽  
Benno Dekker ◽  
...  
Keyword(s):  
Inguinal Hernia ◽  
Antibiotic Prophylaxis ◽  
Wound Infection ◽  
Mesh Repair ◽  
Primary Inguinal Hernia ◽  
Open Mesh Repair ◽  
Open Mesh

Antibiotic prophylaxis for open mesh repair of groin hernia: systematic review and meta-analysis

Hernia ◽  
2016 ◽  
Vol 20 (6) ◽  
pp. 765-776 ◽  
Author(s):  
E. Erdas ◽  
F. Medas ◽  
G. Pisano ◽  
A. Nicolosi ◽  
P. G. Calò
Keyword(s):  
Systematic Review ◽  
Antibiotic Prophylaxis ◽  
Mesh Repair ◽  
Groin Hernia ◽  
Meta Analysis ◽  
Open Mesh Repair ◽  
Open Mesh
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