Impact of Multimodality Pain Regimens on Elective Colorectal Surgery Outcomes

2017 ◽  
Vol 83 (4) ◽  
pp. 414-420
Author(s):  
Jennifer A. Kaplan ◽  
Emily Finlayson ◽  
Andrew D. Auerbach
Keyword(s):  
Colorectal Surgery ◽  
Length Of Stay ◽  
Confidence Interval ◽  
Readmission Rate ◽  
Enhanced Recovery ◽  
Elective Colorectal Surgery ◽  
Lengths Of Stay ◽  
Propensity Matching ◽  
Secondary Analyses ◽  
Enhanced Recovery Programs

Trials of enhanced recovery programs suggest that multimodality pain regimens improve outcomes after colorectal surgery. We sought to determine whether patients receiving postoperative multimodality pain regimens would have shorter lengths of stay without an associated increase in readmission rate as compared to those receiving opioid-based pain regimens. Retrospective cohort study of adults who underwent elective colorectal surgery between January 1, 2006, and December 31, 2012, in a national hospital network participating in the Premier Perspective database. Patients were grouped into multimodality or opioid-based using postoperative medication charges. Primary outcome measures included length of stay and 30-day readmission rate. Among 91,936 patients, 38 per cent received multimodality pain regimens and 61 per cent received opioid-based regimens. After adjustment for patient and surgical characteristics, there was no difference in length of stay or cost, odds of readmission were 1.2 (95% confidence interval = 1.2–1.3, P < 0.001), and odds of mortality were 0.8 (95% confidence interval = 0.6–0.9, P < 0.001) in the multimodality group compared to nonopioid sparing. Our results were consistent in secondary analyses using propensity matching. Fewer than half of patients undergoing elective colorectal surgery in our cohort received multimodality pain regimens, and receipt of these medications was associated with mixed benefits in terms of length of stay, readmission, and mortality.

Laparoscopic approach and patient length of stay in elective colorectal surgery without an enhanced recovery programme

2014 ◽  
Vol 84 (7-8) ◽  
pp. 502-503 ◽  
Author(s):  
Irshad Shaikh ◽  
Mohammed Boshnaq ◽  
Nusrat Iqbal ◽  
Sudhakar Mangam ◽  
George Tsavellas
Keyword(s):  
Colorectal Surgery ◽  
Length Of Stay ◽  
Enhanced Recovery ◽  
Laparoscopic Approach ◽  
Elective Colorectal Surgery ◽  
Enhanced Recovery Programme

scholarly journals ERAS® Program in a Portuguese Hospital: Results from Elective Colorectal Surgery after One Year of Implementation

2020 ◽  
Vol 33 (9) ◽  
pp. 568
Author(s):  
André Carrão ◽  
Daniel Ribeiro ◽  
Maria Manso ◽  
Joana Oliveira ◽  
Luís Féria ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Length Of Stay ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Enhanced Recovery ◽  
Enhanced Recovery After Surgery ◽  
Bowel Function ◽  
Control Group ◽  
Elective Colorectal Surgery ◽  
Improve Patient

Introduction: The Enhanced Recovery After Surgery® program comprises the implementation of various perioperative measures that reduce surgical stress and ultimately improve patient recovery and outcome. The purpose of this study is to evaluate the first-year compliance and clinical outcomes after implementation of the Enhanced Recovery After Surgery® program in elective colorectal surgery in our hospital.Material and Methods: An analysis was performed on the 210 patients who underwent elective colorectal surgery from May 2016 to December 2017. The group of patients that underwent surgery after the protocol implementation (Enhanced Recovery After Surgery® group) was compared to a conventional care control group (pre- Enhanced Recovery After Surgery® group). Differences between the two groups were adjusted using Propensity Score matching. The main outcomes were length of stay, return of bowel function, complications and mortality. The evolution of compliance with Enhanced Recovery After Surgery® principles was also analyzed.Results: After propensity score matching, 112 patients were included in the present study: 56 patients formed the pre-Enhanced Recovery After Surgery® group and 56 the Enhanced Recovery After Surgery® group. The overall adherence to the protocol increased from 35.7% to 80.8%. There was a decrease in length of stay, time to return of bowel function and medical complications.Discussion: The Enhanced Recovery After Surgery® program is safe and seems to shorten length of stay and improve patient recovery and clinical outcome.Conclusion: This study showed that the implementation of the Enhanced Recovery After Surgery® program was possible in Hospital Beatriz Ângelo, with a positive impact in the immediate postoperative recovery of colorectal patients.

scholarly journals Effectiveness and safety of the enhanced recovery program in colorectal surgery: overview of systematic reviews

2020 ◽  
Author(s):  
Kelly Rocío Chacón Acevedo ◽  
Édgar Cortés Reyes ◽  
Óscar Alexander Guevara Cruz ◽  
Jorge Augusto Díaz Rojas ◽  
Lina María Rincón Martínez
Keyword(s):  
Colorectal Surgery ◽  
Length Of Stay ◽  
Systematic Reviews ◽  
Perioperative Care ◽  
Enhanced Recovery ◽  
Hospital Length ◽  
The Body ◽  
Hospital Length Of Stay ◽  
Secondary Outcome ◽  
Elective Colorectal Surgery

Introduction: Multimodal enhanced recovery programs are a new paradigm in perioperative care. Objective: To evaluate the certainty of evidence pertaining to the effectiveness and safety of the multimodal perioperative care program in elective colorectal surgery. Data source: A search was conducted in the Medline, EMBASE, and Cochrane databases, up until February 2020. Eligibility criteria: Systematic reviews that take into account the perioperative multimodal program in patients with an indication for colorectal surgery were included. The primary outcomes were morbidity and postoperative deaths. The secondary outcome was hospital length of stay. Study quality and synthesis method: The reviews were evaluated with AMSTAR-2 and the certainty of the evidence with the GRADE methodology. The findings are presented with measures of frequency, risk estimators, or differences. Results: Six systematic reviews of clinical trials with medium and high quality in AMSTAR-2 were included. Morbidity was reduced between 16 and 48%. Studies are inconclusive regarding postoperative mortality. Hospital length of stay was reduced by an average of 2.5 days (p <0.05). The certainty of the body of evidence is very low. Limitations: The effect of the program, depending on the combination of elements, is not clear. Conclusions and implications: Despite the proven evidence that the program is effective in reducing global postoperative morbidity and hospital stay, the body of evidence is of very low quality. Consequently, results may change with new evidence and further research is required.

scholarly journals A Protocol is not Enough: Enhanced Recovery Program-Based Care and Clinician Adherence Associated with Shorter Stay After Colorectal Surgery

2020 ◽  
Vol 45 (2) ◽  
pp. 347-355
Author(s):  
Ben E. Byrne ◽  
Omar D. Faiz ◽  
Alex Bottle ◽  
Paul Aylin ◽  
Charles A. Vincent
Keyword(s):  
Factor Analysis ◽  
Colorectal Surgery ◽  
Length Of Stay ◽  
Clinical Outcomes ◽  
Enhanced Recovery ◽  
Care Providers ◽  
Elective Colorectal Surgery ◽  
Enhanced Recovery Program ◽  
Care Protocol ◽  
Recovery Program

Abstract Background Randomised trials have shown an Enhanced Recovery Program (ERP) can shorten stay after colorectal surgery. Previous research has focused on patient compliance neglecting the role of care providers. National data on implementation and adherence to standardised care are lacking. We examined care organisation and delivery including the ERP, and correlated this with clinical outcomes. Methods A cross-sectional questionnaire was administered to surgeons and nurses in August–October 2015. All English National Health Service Trusts providing elective colorectal surgery were invited. Responses frequencies and variation were examined. Exploratory factor analysis was performed to identify underlying features of care. Standardised factor scores were correlated with elective clinical outcomes of length of stay, mortality and readmission rates from 2013–15. Results 218/600 (36.3%) postal responses were received from 84/90 (93.3%) Trusts that agreed to participate. Combined with email responses, 301 surveys were analysed. 281/301 (93.4%) agreed or strongly agreed that they had a standardised, ERP-based care protocol. However, 182/301 (60.5%) indicated all consultants managed post-operative oral intake similarly. After factor analysis, higher hospital average ERP-based care standardisation and clinician adherence score were significantly correlated with reduced length of stay, as well as higher ratings of teamwork and support for complication management. Conclusions Standardised, ERP-based care was near universal, but clinician adherence varied markedly. Units reporting higher levels of clinician adherence achieved the lowest length of stay. Having a protocol is not enough. Careful implementation and adherence by all of the team is vital to achieve the best results.

Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies

2020 ◽  
pp. 000313482095484
Author(s):  
Andrés Zorrilla-Vaca ◽  
Gabriel E. Mena ◽  
Juan Cata ◽  
Ryan Healy ◽  
Michael C. Grant
Keyword(s):  
Systematic Review ◽  
Colorectal Surgery ◽  
Observational Studies ◽  
Enhanced Recovery ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Conventional Care ◽  
Recovery Programs ◽  
Enhanced Recovery Programs ◽  
Postoperative Aki

Background Enhanced recovery programs (ERPs) for colorectal surgery bundle evidence-based measures to reduce complications, accelerate postoperative recovery, and improve the value of perioperative health care. Despite these successes, several recent studies have identified an association between ERPs and postoperative acute kidney injury (AKI). We conducted a systematic review and meta-analysis to determine the association between ERPs for colorectal surgery and postoperative AKI. Methodology After conducting a search of major databases (PubMed, Embase, Scopus, Google Scholar, and ScienceDirect), we conducted a meta-analysis of observational studies that reported on the association between ERPs and postoperative AKI. Results Six observational studies (n = 4765 patients) comparing ERP (n = 2140) to conventional care (n = 2625) were included. Overall, ERP patients had a significantly greater odds of developing postoperative AKI (odds ratio [OR] = 1.98, 95% confidence interval [CI] 1.31-3.00, P = .001) than those who received conventional care. There was no evidence of publication bias (Begg’s test P = 1.0, Egger’s P value = .95). Conclusions Based upon pooled results from observational studies, ERPs are associated with increased odds of developing postoperative AKI compared to conventional perioperative care. The mechanism for this effect is likely multifactorial. Additional research targeting high risk patient populations should evaluate the role of restrictive fluid administration, hemodynamic goals, and scheduled nephrotoxic agents in ERP protocols.

Successful Implementation of Enhanced Recovery in Elective Colorectal Surgery is Variable and Dependent on the Local Environment

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Chelsea P. Fischer ◽  
Leandra Knapp ◽  
Mark E. Cohen ◽  
Clifford Y. Ko ◽  
Elizabeth C. Wick
Keyword(s):  
Colorectal Surgery ◽  
Enhanced Recovery ◽  
Local Environment ◽  
Successful Implementation ◽  
Elective Colorectal Surgery
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