Complete Spontaneous Regression of Merkel Cell Carcinoma

2005 ◽  
Vol 114 (5) ◽  
pp. 376-380 ◽  
Author(s):  
Luis Junquera ◽  
Aintza Torre ◽  
Luis García-Consuegra ◽  
Juan C. Vicente ◽  
Manuel F. Fresno
Keyword(s):  
Computed Tomography ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Spontaneous Regression ◽  
Case Reports ◽  
The Elderly ◽  
Merkel Cell ◽  
Review Of The Literature ◽  
The Right

Merkel cell carcinoma (MCC) is a very aggressive primary cutaneous neoplasm most often occurring on the head and neck of the elderly. Spontaneous regression of MCC was first described in 1986. A 79-year-old woman with MCC on the right cheek underwent spontaneous regression of the malignancy, documented by photographic follow-up, computed tomography, and histologic studies. A review of the literature is presented. Complete clinical and histologic regression of MCC was observed in the present case. Although the literature documents 11 similar cases, only 6 can be regarded as complete spontaneous regressions following exclusive performance of a biopsy (primary complete spontaneous regression). Primary complete spontaneous regression of MCC is infrequent, and most case reports describe this phenomenon in women with MCC on the cheek. The reasons underlying regression are unknown.

Merkel cell carcinoma of the gluteal region: a rare case report and literature review

2021 ◽  
pp. 1-8
Author(s):  
Mahmut Corapli ◽  
Burcin Pehlivanoglu ◽  
Haci Taner Bulut ◽  
Huseyin Alakus ◽  
Nadiye Akdeniz
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Survival Rates ◽  
Gluteal Region ◽  
Adjuvant Chemoradiotherapy ◽  
Merkel Cell ◽  
Neuroendocrine Cancer ◽  
Rare Case Report ◽  
The Right

Abstract Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine cancer that shows aggressive biologic behavior. Although it usually occurs in sun-exposed areas, it can rarely be seen in non-sun-exposed sites. Here, we present a 66-year-old woman with MCC arising from the right gluteal region that was treated wide excision and adjuvant chemoradiotherapy. In the 24th month follow-up, the case was disease and recurrence free, representing the longest survival among patients with gluteal MCC. Early diagnosis and treatment are important to improve survival rates in patients with non-sun-exposed MCC. Keywords: Merkel cell carcinoma, non-sun-exposed, Continuous...

Giant Merkel Cell Carcinoma of the Lower Limb: Case Report and Review of the Literature

2013 ◽  
Vol 17 (5) ◽  
pp. 351-355 ◽  
Author(s):  
Andrea Marchesi ◽  
Pier Camillo Parodi ◽  
Marco Brioschi ◽  
Giorgio Sileo ◽  
Matteo Marchesi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Poor Prognosis ◽  
Lymph Node Biopsy ◽  
Lower Limbs ◽  
Merkel Cell ◽  
Review Of The Literature ◽  
Node Biopsy ◽  
Surgical Excisions

Background:Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy that usually grows rapidly at the head and neck. Giant forms at the lower limbs are rarely reported and usually affect patients in the eighth decade or older.Methods:We report the case of a 60-year-old man who presented with a giant MCC on his right thigh. We managed this case by applying the 2012 updated guidelines and reviewed all cases of giant MCC of the lower limbs reported in the literature.Results:At the 4-month follow-up, the patient showed complete remission.Conclusion:Giant forms of MCC are still treated as typical cases of MCC, when these patients show a very poor prognosis. In young and adult people, such as our case, wide surgical excisions, sentinel lymph node biopsy in clinically negative node cases, radiotherapy of the regional drain area, and a strict follow-up should be routinely performed to improve patients' survival.

scholarly journals Salvage Robotic-Assisted Seminal Vesiculectomy for Merkel Cell Carcinoma Metastasis

2021 ◽  
Vol 34 (13) ◽  
Author(s):  
Luisa Jerónimo Alves ◽  
Bruno Graça ◽  
Kris Maes
Keyword(s):  
Cell Carcinoma ◽  
Seminal Vesicle ◽  
Merkel Cell Carcinoma ◽  
Lymph Node Involvement ◽  
Merkel Cell ◽  
Robotic Assisted ◽  
Inguinal Lymphadenectomy ◽  
Node Involvement ◽  
The Right

A 71-year-old male presented with Merkel cell carcinoma along with inguinal lymph node involvement (stage III). The patient was proposed for systemic treatment followed by inguinal lymphadenectomy and adjuvant radiotherapy. During the follow-up period, recurrences were documented (lymphatic and visceral) and were treated with salvage surgery and radiotherapy. On the fifth year of follow-up the patient was diagnosed with a metastasis in the right seminal vesicle and underwent stereotactic body radiation therapy. Two-years later, tumor recurrence in the right seminal vesicle was managed with salvage robotic assisted seminal vesiculectomy. Advanced stages of Merkel cell carcinoma have a poor outcome and salvage treatments should be tailored to each patient. A multidisciplinary approach was crucial in achieving successful outcomes. The patient is still recurrence free twenty-four months after surgery. To the best of our knowledge, this is the first publication reporting a seminal vesical Merkel cell metastasis.

scholarly journals Merkel cell carcinoma in organ transplant recipients: Case reports and review of the literature

2015 ◽  
Vol 1 (6) ◽  
pp. S29-S32 ◽  
Author(s):  
Giorgia L. Garrett ◽  
Hanieh Zargham ◽  
Joshua M. Schulman ◽  
Fatemeh Jafarian ◽  
Siegrid S. Yu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Case Reports ◽  
Organ Transplant ◽  
Merkel Cell ◽  
Transplant Recipients ◽  
Review Of The Literature ◽  
Organ Transplant Recipients

Complete spontaneous regression of primary Merkel cell carcinoma with tumoural infiltration: a systematic review

2021 ◽  
Vol 31 (3) ◽  
pp. 381-391
Author(s):  
Laurie Ah-Thiane ◽  
Mahtab Samimi ◽  
Thibault Kervarrec ◽  
Amir Khammari ◽  
Brigitte Dréno
Keyword(s):  
Systematic Review ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Spontaneous Regression ◽  
Merkel Cell

Merkel Cell Carcinoma of the Eyelid: A Case Report

2000 ◽  
Vol 10 (2) ◽  
pp. 173-176 ◽  
Author(s):  
L. Collaço ◽  
J.P. Silva ◽  
M. Gonçalves ◽  
P. Abrantes
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Neuroendocrine Tumour ◽  
The Elderly ◽  
Primary Site ◽  
Wide Resection ◽  
Merkel Cell ◽  
Unique Case ◽  
Upper Eyelid

A 22-year-old woman who presented with a tumour of the upper eyelid with clinical, histological, immunohistochemical and ultrastructural features of a Merkel cell carcinoma is reported. This is a unique case of Merkel cell carcinoma in such a young patient. This neuroendocrine tumour is typically found in the elderly. It can grow rapidly, has the potential for local recurrence and early metastatic spread. The authors recommend wide resection of the primary site, which proved effective in this case.

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