Merkel Cell Carcinoma of the Eyelid: A Case Report

2000 ◽  
Vol 10 (2) ◽  
pp. 173-176 ◽  
Author(s):  
L. Collaço ◽  
J.P. Silva ◽  
M. Gonçalves ◽  
P. Abrantes

A 22-year-old woman who presented with a tumour of the upper eyelid with clinical, histological, immunohistochemical and ultrastructural features of a Merkel cell carcinoma is reported. This is a unique case of Merkel cell carcinoma in such a young patient. This neuroendocrine tumour is typically found in the elderly. It can grow rapidly, has the potential for local recurrence and early metastatic spread. The authors recommend wide resection of the primary site, which proved effective in this case.

Author(s):  
Soulé-Martínez Christian Enrique ◽  
Monroy-Ramírez Miguel Angel ◽  
Jaimes-Durán Edwing Michel ◽  
Castellanos-Aguilar Leonel ◽  
Ricarte-Almeida Eros Rafael ◽  
...  

Merkel cell carcinoma (MCC) is a rare, but highly aggressive, malignant neuroendocrine tumor, with a higher prevalence in men, Caucasians, and the elderly. It is usually identified in photo-exposed areas such as the head, trunk, and extremities. It is related to locoregional recurrences and metastases, which conditions a high mortality rate. Currently, the pathogenesis is unclear, but it is related to ultraviolet radiation, immunosuppression, and polyomavirus infection. Prompt diagnosis and treatment are essential to improve the survival rate.


Author(s):  
Soo Jung Gong ◽  
Su Jung Shim

Abstract Introduction: Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumour. Although surgical resection is a treatment choice, it often occurs in the head and neck and occurs mainly in the elderly, making surgery impossible. Radical radiation therapy may be an alternative to surgery in these patients. In addition, radiation treatment may be performed even after recurrence after surgery. Methods: An 82-year-old MCC patient had cT2N0M0, stage IIA MCC on the left cheek that metastasised to lymph node 2 months after surgery. She was treated with radiation monotherapy with a hypofractionation schedule (39 Gy at 3 Gy per fraction). Results: The patient achieved complete remission after radiotherapy without severe toxicities.


2009 ◽  
Vol 3 (1) ◽  
Author(s):  
Tamara Turk ◽  
Zeljka Crncevic Orlic ◽  
Ivana Smoljan ◽  
Antica Nacinovic ◽  
Irena Seili Bekafigo ◽  
...  

2017 ◽  
Vol 8 (1) ◽  
pp. 190 ◽  
Author(s):  
Rosario Maugeri ◽  
Antonella Giugno ◽  
RobertoG Giammalva ◽  
Carlo Gulì ◽  
Luigi Basile ◽  
...  

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