Malignant External Otitis: Further Considerations

1977 ◽  
Vol 86 (4) ◽  
pp. 417-428 ◽  
Author(s):  
James R. Chandler

Malignant external otitis is an infection which begins in the external auditory canal. It is uniformly caused by the Gram negative Pseudomonas aeruginosa organism and mainly affects elderly diabetics. It spreads to the soft tissues beneath the temporal bone and, if not properly treated leads to facial nerve palsy, mastoiditis, sepsis, osteomyelitis of the base of the skull, sigmoid sinus thrombosis, multiple cranial nerve palsies and death. Experience with 72 patients in varying stages of the disease is summarized. Stressed are the diagnostic criteria of nonresponsiveness to the usual methods of treatment, continued suppuration, and the continuing reformation of granulation tissue in the floor of the external auditory canal. Medical treatment is recommended with hospitalization and intravenous carbenicillin and gentamicin. Minor surgical debridement is helpful. All patients should be treated medically for as long as improvement continues, reserving surgical intervention only in the event a plateau is reached or symptoms and signs become worse under treatment. With or without a major surgical procedure, it is imperative to continue treatment for at least seven days after apparent cure in order to avoid recurrent disease possibly at a site distant from the canal.

Dose-Response ◽  
2020 ◽  
Vol 18 (4) ◽  
pp. 155932582096391
Author(s):  
Salvatore Ferlito ◽  
Antonino Maniaci ◽  
Milena Di Luca ◽  
Calogero Grillo ◽  
Lorenzo Mannelli ◽  
...  

Purpose: The progression of the otitic infectious process toward diseases of particular severity is often unpredictable, just as it is challenging to manage the patient over time, even after the apparent resolution of the disease. We aim to define a radiological reading key that allows us to correctly and promptly treat the disease, avoiding the possible severe complications. Methods: We conducted a retrospective study of 13 cases of basal cranial osteomyelitis (SBO) due to malignant external otitis, by the ENT Department of the University of Catania. Through a standardized approach and following the latest guidelines, we have evaluated all patients performing a standardized and personalized radiological protocol according to the stage of the patient’s pathology and modulating the treatment consequently. Results: Clinical signs have been observed such as otorrhea (100%), otalgia in 13/13 patients (100%), granulations in external auditory canal (100%), preauricular cellulitis in 9/13 patients (69%) headache 6/13 cases (46%), dysphonia 4/13 cases (31%). HRCT of the temporal bone proved useful in identifying even minimal bone lesions in 13/13 (100%) while improving MRI in vascular and nervous involvement, although in 1/13 patient with nerve palsy clinical symptomatology preceded radiological evidence. The 99mTc 3-phase planar bone scintigraphy was positive for SBO in 9/13 cases (69%) during the initial phase and, in 100% of the cases in images delayed to 2-3 hours. Subsequent checks up to 1 year, using the Ga 67 scintigraphy, excluded the presence of recurrences in 100% of patients. Conclusion: The osteomyelitis of the base of the skull is a severe complication of malignant external otitis, often not always easily diagnosed. Recurrence can occur up to 1 year after stopping therapy. Imaging techniques such as Tc and MRI are relevant for the initial diagnostic approach and the staging of the pathology and its complications. Nuclear medicine imaging plays a fundamental role in the evaluation of related osteoblastic activity, especially in the remission phase of the disease.


2014 ◽  
Vol 99 (793) ◽  
pp. 162-164
Author(s):  
Mª del Pilar Navarro-Paule ◽  
Raquel Redondo-Luciañez ◽  
Nuria Salas-Barrios ◽  
J. J. Sánchez-Blanco

1992 ◽  
Vol 106 (1) ◽  
pp. 5-6 ◽  
Author(s):  
Osama El-Silimy ◽  
M. Sharnuby

AbstractMalignant external otitis is a progressive pseudomonal infection of the external auditory canal and adjacent structures. In the literature there is no unified policy regarding the management of malignant external otitis. The development of an effective nuclear scanning method and antibiotics active against Pseudomonas aeruginosa have helped in formulating our management policy. A review of four years personal experience with this condition is presented. All of our cases were cured from the disease with no fatality. Gallium67 citrate scans showed that antipseudomonal treatment should continue for up to three months.


IDCases ◽  
2020 ◽  
Vol 22 ◽  
pp. e00945
Author(s):  
Rodrigo Queiroz Silveira ◽  
Viviane Tavares Carvalho ◽  
Haline Novais Cavalcanti ◽  
Fabiana Carraro Eduardo Rodrigues ◽  
Caroline Bittar Braune ◽  
...  

1996 ◽  
Vol 116 ◽  
pp. 3-16 ◽  
Author(s):  
Luca Amorosa ◽  
Giovanni Carlo Modugno ◽  
Antonio Pirodda

1996 ◽  
Vol 116 (sup521) ◽  
pp. 3-16 ◽  
Author(s):  
Luca Amorosa ◽  
Giovanni Carlo Modugno ◽  
Antonio Pirodda

1994 ◽  
Vol 108 (6) ◽  
pp. 492-493 ◽  
Author(s):  
W. C. Lee ◽  
J. F. Sharp

AbstractMalignant external otitis is classically associated with insulin-dependent diabetes mellitus probably due to generalized systemic immunodeficiency (Mowet and Baum, 1971). A unique case of malignant external otitis associated with Waldenstrom's macroglobulinaemia is presented.


1989 ◽  
Vol 103 (4) ◽  
pp. 366-368 ◽  
Author(s):  
J. Bernheim ◽  
J. Sade

AbstractReports concerning the lesions of the skin coverage of the external ear canal in malignant external otitis (M.E.O.) are very few. To evaluate this problem, we studied the skin lesions of 45 skin biopsies from 40 M.E.O. patients, 23 from regions covering the osseous part of the ear structure, seven from the cartilaginous part of the external canal and 15 from both parts. The epidermis was normal in nine, thickened in 16, with acanthotic thickening and pseudoepitheliomatous hyperplasia in 20. In the dermis the amount of collagen was normal, but it was infiltrated by the inflammatory process. Acute inflammation was observed in 16 biopsies, subacute in 23, chronic in six. A mixture of acute and chronic changes was present in 18 biopsies. No major abnormalities of the vasculature could be detected. The distinguishing pathological feature of M.E.O. concerns the typical topographic distribution of the inflammation in the osseous part of the external ear canal.


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