Basaloid-Squamous Carcinomas of the Upper Aerodigestive Tracts

Basaloid-squamous carcinoma is a new addition to the lexicon of variants of squamous cell carcinoma. The carcinoma is distinctive histologically, is biologically high grade, and manifests a predilection for the base of tongue, hypopharynx, and supraglottic larynx.

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Basaloid Squamous Carcinoma of the Head and Neck Immunohistochemical Comparison With Adenoid Cystic Carcinoma and Squamous Cell Carcinoma

Archives of Otolaryngology - Head and Neck Surgery ◽

10.1001/archotol.1993.01880200093013 ◽

1993 ◽

Vol 119 (8) ◽

pp. 887-890 ◽

Cited By ~ 61

Author(s):

J. Klijanienko ◽

A. El-Naggar ◽

A. Ponzio-Prion ◽

P. Marandas ◽

C. Micheau ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Adenoid Cystic Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Squamous Carcinoma ◽

Basaloid Squamous Carcinoma ◽

Adenoid Cystic ◽

Basaloid Squamous

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Basaloid squamous carcinoma: A clinical comparison of two histologic types with poorly differentiated squamous cell carcinoma

Otolaryngology ◽

10.1016/s0194-5998(98)70104-4 ◽

1998 ◽

Vol 119 (5) ◽

pp. 471-475 ◽

Cited By ~ 46

Author(s):

Sandra M. Winzenburg ◽

Gloria A. Niehans ◽

George Evan ◽

Daly Kathleen ◽

George L. Adams

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Squamous Carcinoma ◽

Basaloid Squamous Carcinoma ◽

Clinical Comparison ◽

Poorly Differentiated ◽

Histologic Types ◽

Basaloid Squamous

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Clinicopathologic Characteristics and Clinical Outcomes of Esophageal Basaloid Squamous Carcinoma: Experience at a Single Institution

International Surgery ◽

10.9738/cc195 ◽

2013 ◽

Vol 98 (4) ◽

pp. 450-454 ◽

Cited By ~ 6

Author(s):

Youichi Kumagai ◽

Koji Nagata ◽

Toru Ishiguro ◽

Norihiro Haga ◽

Kohki Kuwabara ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Clinical Outcomes ◽

Squamous Cell ◽

Squamous Carcinoma ◽

Venous Invasion ◽

Clinicopathologic Characteristics ◽

Pathologic Stage ◽

Basaloid Squamous Carcinoma ◽

Basaloid Squamous

Abstract This retrospective study investigated the clinicopathologic characteristics and clinical outcomes of esophageal basaloid squamous carcinoma (BSC). Among 190 patients with esophageal carcinoma treated surgically between 1998 and 2011, we identified 9 (4.7%) with BSC. All of the patients were male, with a median age of 65 years. The frequencies of venous invasion, lymphatic invasion, and lymph node metastasis were 56%, 89%, and 67%, respectively. A total of 2 patients were pathologic stage 1, 5 were stage 2, and 2 were stage 3. Tumor recurrence was observed in 56% of the patients. The 5-year survival rate for patients with esophageal BSC was 40%, which was compatible with the figure of 53.8% for control patients (n = 18) with typical squamous cell carcinoma matched for sex, age, tumor location, and pathologic stage (P = 0.45). Although esophageal BSC shows aggressive lymph-vascular invasion and has a high likelihood of recurrence, its prognosis seems identical to that of typical squamous cell carcinoma.

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Basaloid squamous cell carcinoma of the supraglottic larynx

European Archives of Oto-Rhino-Laryngology ◽

10.1007/s004050050213 ◽

2000 ◽

Vol 257 (3) ◽

pp. 154-157 ◽

Cited By ~ 25

Author(s):

B. Erdamar ◽

Y. Suoglu ◽

M. Sirin ◽

C. Karatay ◽

S. Katircioglu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Basaloid Squamous Cell Carcinoma ◽

Supraglottic Larynx ◽

Basaloid Squamous

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A Basaloid Squamous Cell Carcinoma of the Supraglottic Larynx

Pathology Case Reviews ◽

10.1097/pcr.0b013e3182248b1f ◽

2011 ◽

Vol 16 (4) ◽

pp. 167-172

Author(s):

Anne McGehee Mills ◽

Edward B. Stelow ◽

Stacey E. Mills

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Basaloid Squamous Cell Carcinoma ◽

Supraglottic Larynx ◽

Basaloid Squamous

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Basaloid Squamous Cell Carcinoma of the Head and Neck: Clinicopathological Features and Differential Diagnosis

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949610500115 ◽

1996 ◽

Vol 105 (1) ◽

pp. 75-82 ◽

Cited By ~ 84

Author(s):

Leon Barnes ◽

Christina MacMillan ◽

Alfio Ferlito ◽

Alessandra Rinaldo ◽

Giuseppe Altavilla ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Prognostic Significance ◽

Squamous Carcinoma ◽

Basaloid Squamous Cell Carcinoma ◽

Small Cell Neuroendocrine Carcinoma ◽

Basal Cell Adenocarcinoma ◽

Carcinoma Squamous Cell ◽

Basaloid Squamous

Basaloid squamous cell carcinoma is a recently recognized variant of squamous cell carcinoma. The lesion is histologically distinctive and manifests a predilection for the supraglottis, pyriform sinus, and tongue base. The immunohistochemical profile is discussed. The differential diagnoses include adenoid cystic carcinoma, small cell neuroendocrine carcinoma, basal cell adenocarcinoma, adenosquamous carcinoma, squamous cell carcinoma, spindle cell squamous carcinoma, mucoepidermoid carcinoma, and adenoid squamous cell carcinoma. Basaloid squamous cell carcinoma is a biologically high-grade tumor with a propensity for nodal as well as systemic metastases. It is a morphologic and phenotypic entity with a separate prognostic significance.

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