Regression of Post-orthodontic Lesions by a Remineralizing Cream

2009 ◽  
Vol 88 (12) ◽  
pp. 1148-1153 ◽  
Author(s):  
D.L. Bailey ◽  
G.G. Adams ◽  
C.E. Tsao ◽  
A. Hyslop ◽  
K. Escobar ◽  
...  
Keyword(s):  
Clinical Trial ◽  
White Spot ◽  
White Spot Lesion ◽  
White Spot Lesions ◽  
Lesion Formation ◽  
Clinical Assessments ◽  
Increased Risk ◽  
Icdas Ii ◽  
Orthodontic Patients ◽  
Casein Phosphopeptide

Orthodontic patients have an increased risk of white-spot lesion formation. A clinical trial was conducted to test whether, in a post-orthodontic population using fluoride toothpastes and receiving supervised fluoride mouthrinses, more lesions would regress in participants using a remineralizing cream containing casein phosphopeptide- amorphous calcium phosphate compared with a placebo. Forty-five participants (aged 12–18 yrs) with 408 white-spot lesions were recruited, with 23 participants randomized to the remineralizing cream and 22 to the placebo. Product was applied twice daily after fluoride toothpaste use for 12 weeks. Clinical assessments were performed according to ICDAS II criteria. Transitions between examinations were coded as progressing, regressing, or stable. Ninety-two percent of lesions were assessed as code 2 or 3. For these lesions, 31% more had regressed with the remineralizing cream than with the placebo (OR = 2.3, P = 0.04) at 12 weeks. Significantly more post-orthodontic white-spot lesions regressed with the remineralizing cream compared with a placebo over 12 weeks.

Control of White Spot Lesions with Use of Fluoride Varnish or Chlorhexidine Gel During Orthodontic Treatment A Randomized Clinical Trial

2016 ◽  
Vol 40 (4) ◽  
pp. 274-280 ◽  
Author(s):  
M Restrepo ◽  
D G Bussaneli ◽  
F Jeremias ◽  
RCL Cordeiro ◽  
DB Raveli ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Experimental Period ◽  
Orthodontic Brackets ◽  
White Spot ◽  
Fluoride Varnish ◽  
Controlled Clinical Trial ◽  
White Spot Lesions ◽  
Diagnodent Pen ◽  
Orthodontic Patients ◽  
Chlorhexidine Gel

Objective: To compare the effectiveness of fluoride varnish and 2% chlorhexidine gel for controlling active white spot lesions (WSLs) adjacent to orthodontic brackets. Study design: Thirty-five orthodontic patients (17.2 ± 2.3 years old) presenting 60 WSLs adjacent to orthodontic brackets were enrolled in this randomized, blind, 3-armed and controlled clinical trial. The patients were randomly allocated to 1 of 3 arms: (1) two applications of 5% NaF varnish- F, with one-week interval, (2) two applications of 2% chlorhexidine gel-CHX, with one-week interval and (3) usual home care-control (CO). The WSLs were scored by using a DIAGNOdent pen. An independent examiner scored the surfaces using Nyvad criteria for caries assessment. Results: A total of thirty patients presenting 51 lesions completed the study. All treatments reduced the fluorescence values during the experimental period; however, F induced faster remineralization than CHX. After 3 months, 70.58 % were inactive considering all groups. DIAGNOdent pen and Nyvad presented a significant correlation. Conclusion: After 3 months of treatment, F, CHX and CO were capable of controlling the WSLs adjacent to the orthodontic brackets. However, the treatment with F was capable of controlling the progression of the WSLs in a shorter period of time.

scholarly journals In-vivo durability of a fluoride-releasing sealant (OpalSeal) for protection against white-spot lesion formation in orthodontic patients

2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Michael Knösel ◽  
David Ellenberger ◽  
Yvonne Göldner ◽  
Paulo Sandoval ◽  
Dirk Wiechmann
Keyword(s):  
White Spot ◽  
White Spot Lesion ◽  
Lesion Formation ◽  
Orthodontic Patients

scholarly journals Comparison of the effects of toothpastes containing nanohydroxyapatite and fluoride on white spot lesions in orthodontic patients: A randomized clinical trial

2020 ◽  
Vol 17 (5) ◽  
pp. 354
Author(s):  
Asghar Ebadifar ◽  
Mohammadreza Badiee ◽  
Nima Jafari ◽  
Sayedali Fatemi ◽  
Nazila Ameli ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
White Spot ◽  
White Spot Lesions ◽  
Orthodontic Patients

scholarly journals COLOR CHANGES OF POST-DEBONDING WHITE SPOT LESION AFTER MICROABRASION TECHNIQUE WITH FLUORIDE AND CASEIN PHOSPHOPEPTIDE-AMORPHOUS CALCIUM PHOSPHATE APPLICATION

2018 ◽  
Vol 11 (13) ◽  
pp. 196
Author(s):  
Irene Pratami Angriawan ◽  
Haru Setyo Anggani ◽  
Haru Setyo Anggani ◽  
Nada Ismah ◽  
Nada Ismah
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Color Change ◽  
White Spot ◽  
White Spot Lesion ◽  
White Spot Lesions ◽  
Solution Ph ◽  
Color Changes ◽  
Significant Difference ◽  
Casein Phosphopeptide

 Objective: The prevalence of enamel demineralization among patients after orthodontic treatment is about 50%, which begins with the formation of white spot lesions. The presence of these lesions causes esthetic problems. The aim of this study was to quantify the color changes in post-debonding white spot lesions after microabrasion technique with fluoride and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) application.Materials and Methods: This study used 42 first premolar teeth that had been extracted, then were soaked for 96 h in a demineralization solution (pH 4, 37°C) to form an artificial white spot lesions. Samples were randomly divided into three treatment groups (n=14): (A) Microabrasion technique only; (B) microabrasion technique with 10% CPP-ACP paste application; and (C) microabrasion technique with 1.23% APF gel application. All groups were assigned to pH cycling for 10 days. The color change was determined using spectrophotometer at 3 different time points, which were measured before and after production of the artificial white spot lesions, and after the artificial white spot lesions were treated.Results: This study showed that there was a significant difference in the color of the artificial white spot lesions after microabrasion technique with CPP-ACP application.Conclusion: Microabrasion technique with CPP-ACP application was giving better result in changing the color of white spot lesions than only microabrasion technique and microabrasion technique with fluoride application.

Comparision of two fluoride varnishes for controlling white spot lesions. Randomized clinical trial

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Jesús Alberto Luengo - Fereira
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
White Spot ◽  
Controlled Clinical Trial ◽  
White Spot Lesions ◽  
Randomized Controlled Clinical Trial ◽  
Chi Square ◽  
Randomized Controlled ◽  
Anterior Teeth ◽  
The Mean

Objective: To compare two fluorinated varnishes for the control of white spot lesions.Material and Methods: A randomized controlled clinical trial was conducted. A total of 103 active whitespot lesions on permanent upper anterior teeth from 24 patients, aged 7 to 9 years were randomly assigned totwo groups, G1: Duraphat® (n=52) and G2: DuraShield® (n=51). Weekly applications were perform for fourconsecutive weeks. Fifth week the dimension, regression and activity of the lesions were evaluated. Student’sT test, Wilcoxon Ranks and Chi square were used at 5% significance. Results: At the end of the study, the lesion reduction was observed in 69.7%, finding significant differences(p<0.05) in the mean of the initial and final dimensions in general (2.74 mm to 1.91 mm) and in each group, G1(2.84 mm to 2.03 mm), G2 (2.64 mm to 1.78 mm). In the activity of the lesions, it was found in the G1, 12 active and6 inactive lesions; while in G2, there were 14 active and 29 inactive; these differences were significant (p<0.05). Conclusions: The two evaluated products showed similar clinical efficacy in the remineralization of activewhite spot lesions after 4 weeks of therapy.

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